John H. Krystal, MD

Robert L. McNeil, Jr. Professor of Psychiatry and Professor of Neurobiology; Chair, Department of Psychiatry; Chief of Psychiatry, Yale-New Haven Hospital; Director: NIAAA Center for the Translational Neuroscience of Alcoholism ; Director, Clinical Neuroscience Division, VA National Center for PTSD; Director, VA Alcohol Research Center; Medical Director, Schizophrenia Biological Research Center, DVA

Clinical Trials

Conditions Study Title
The Sustained Effects of Ketamine
Biomarker Assessment of Glutamatergic Target Engagement-RCT
Examining Cognition, Emotion, and Individual Differences in Schizophrenia
Genetics of Alcohol Dependence: Family Controlled Linkage Disequilibrium Studies and Mapping by Admixture Linkage Disequilibrium (MALD)
GABA Mechanisms Underlying the Vulnerability for Alcohol Dependence
GABA-Glutamate Interactions and Psychosis
Biomarkers of Clinical Subtype and Treatment Response in Obsessive-Compulsive Disorder
Glial and Glutamatergic Deficits In Post Traumatic Stress Disorder (PTSD)
Prefrontal cortex and working memory deficits in schizophrenia: a functional magnetic resonance imaging study
Examination of glutamate and mGLuR5 in psychiatric disorders
Intravenous Alcohol Administration Using the BrAc Method in Healthy Subjects with and without a Family History of Alcoholism
GABA-Dopamine Interactions and Psychosis
GABRA2 Modulation of NMDA Receptor Deficit-Related Prefrontal Cortex Dysfunction
Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
PET imaging of mGluR5 with drug challenge
Psychotomimetic Effets of the Kappa Opioid Receptor Agonist Salvinorin A in Healthy Humans
Functional Magnetic Resonance Imaging Study of Mood Disorders
Translational Neuroscience Optimization of GlyT1 Inhibitor
Examining The Effect Of Ketamine on Glutamate/Glutamine Cycling
PET Imaging of Microglia with [11C]PBR28 in alcohol dependent and healthy controls subjects

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