Instruments & Rates

Instrument Photos

Transmission Electron Microscopes

FEI Tecnai G2 Spirit BioTWIN 

This Lab6 emission, 80 kV microscope is optimized for examining biological specimen with either plastic or cryo sections, and routine negative stained samples. It is equipped with a SIS Morada 11 megapixel CCD camera. The setup provides quick viewing on a large area and good quality and contrast digital imaging.

- Not applicable

Transmission Electron Microscopes

FEI Tecnai G2 Spirit TWIN (T12) 

The LaB6 emission, 120 kV microscope can operated at both room temperature or cryo modes, it is suitable for applications such as sample screening in negative staining, particle recongnition and analysis in material, and cryo EM imaging. It is equipped with a Gatan has an UltraScan 4000 (4k x 4k) CCD camera, and a TV-camera.

- Not applicable

Transmission Electron Microscopes

FEI Tecnai F20 Cryo EM 

The FEI Tecnai F20 microscope has a Schottky Field Emission source and operates at 200 kV, equipped with a Gatan K2 Summit Direct Detection Camera and an UltraScan 4000 (4k x4k) CCD camera. It is dedicated for high-resolution single particle imaging and cryo electron tomography. There are multiple Gatan cryo holders available along with a FEI room-temperate holder. 

The facility also provides access to SGI graphics workstations and maintains image processing software packages for single particle and electron crystallographic applications. Access to the Yale supercomputer network is also available.

- Not applicable

Transmission Electron Microscopes

FEI Tecnai G2 F20 XT X-TWIN (TF20 TOMO) 

The 200kV FEI Tecnai F20 X-Twin with a Schottky field emitter is designed to produce optimal high resolution performance in both TEM and STEM. This microscope features a 4k x 4k Eagle CCD camera. It equipped with a high angle annular dark-filed (HAADF) detector, and an EDAX Pulse processor. The setup uses FEI Xplore3D software for electron tomography data acquisition. We have a 30 degree tilt FEI double-tilt holder, and a 70 degree high-tilt tomography holder,

- Not applicable

Biological Specimen Preparation

LEICA CPD300

- Not applicable

Biological Specimen Preparation

PELCO BioWave Pro microwave tissue processor

- Not applicable

Biological Specimen Preparation

Leica EM HPM 100 high pressure freezer

- Not applicable

Biological Specimen Preparation

Leica EM AFS2 freeze substitution machine

- Not applicable

Ultramicrotomes

Leica EM UC7 ultramicrotome

- Not applicable

Ultramicrotomes

Leica EM FC6/UC6 cryo-ultramicrotome


- Not applicable

Cryo EM Sample Preparation

FEI Vitrobot

- Not applicable

Cryo EM Sample Preparation

Bal-Tec SCD 005 sputter coaters

- Not applicable

Cryo EM Sample Preparation

Gatan Solarus Advanced plasma system (Model 950)

- Not applicable

Biological Specimen Preparation

LEICA CM 1950

- Not applicable

Carbon Evaporators

Leica EM ACE 600 high vacuum coater 

This high vacuum evaporator is designed to produce very thin, fine-grained and conductive metal and carbon coatings for highest resolution EM analysis.

- Not applicable

Carbon Evaporators

Leica EM ACE 200 low vacuum coater 

This machine is used for making carbon thin film on EM grids, it has a quartz thickness measurement, provides quick and reproducible results.

- Not applicable

Additional Equipment

  • Image analysis workstation
  • Olympus BX51 optical/fluorescence microscope
  • Olympus CK2 cell culture microscope
  • Leica CM1950 cryostat
  • Leica EM KMR2 knife maker