19F-MRS (Magnetic Resonance Spectroscopy) Studies of in-vivo 5-Fluorouracil Pharmacokinetics with and without Bevacizumab in Patients with Liver Metastases from Adenocarcinoma of the colon
Disease/Condition: Colon Cancer
Principal Investigator: Howard S Hochster |
A Multicenter, Open Label, Phase II Study of Bendamustine and Rituximab followed by 90-yttrium (Y) Ibritumomab Tiuxetan for Untreated Follicular Lymphoma (Fol-BRITe)
Disease/Condition: Follicular Lymphoma
Principal Investigator: Dennis L. Cooper |
A Multi-Center, Phase 3, Double-Blind, Randomized, and Controlled Trial of KD019 vs Erlotinib in Subjects With Stage IIIB/IV Non-Small Cell Lung Cancer Who Have Progressed After First- or Second-Line Chemotherapy
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Daniel Morgensztern |
A Multi-center, Placebo-controlled, randomized pilot study of the effect of Sorafenib on Portal Pressure in Patients with Cirrhosis, Significant Portal Hypertension and Hepatocellular Carcinoma Treated with Ablative Therapy and/or Transarterial Chemoembolization
Disease/Condition: Hepatocellular Carcinoma
Principal Investigator: Guadalupe Garcia-Tsao |
A Multicenter, Randomized, Double-Blind, Phase 3 Study of Ramucirumab (IMC-1121B) Drug Product and Best Supportive Care (BSC) Versus Placebo as Second-Line Treatment in Patients With Hepatocellular Carcinoma Following First-Line Therapy With Sorafenib
Disease/Condition: Hepatocellular Carcinoma | Liver Cancer
Principal Investigator: Stacey M Stein |
A Phase 1, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of Ascending Doses of AZD4547 in Patients with Advanced Solid Tumor Malignancies
Disease/Condition: Advanced Solid Cancers
Principal Investigator: Howard S Hochster |
A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113
Disease/Condition: Advanced Malignancies | Anaplastic Large Cell Lymphoma | Carcinoma, Non-Small-Cell Lung | Diffuse Large Cell Lymphoma | Inflammatory Myofibroblastic Tumors
Principal Investigator: Scott Nicholas Gettinger |
A Phase 2 Biomarker Study of Elotuzumab (Humanized anti-CS1 Monoclonal IgG1 Antibody) Monotherapy to Assess the Association Between NK Cell Status and Efficacy in High Risk Smoldering Myeloma
Disease/Condition: Smoldering Myeloma
Principal Investigator: Madhav V. Dhodapkar |
A Phase 3, Randomized, Double-Blind Trial of Weekly Paclitaxel Plus AMG 386 or Placebo in Women With Recurrent Partially Platinum Sensitive or Resistant Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers
Disease/Condition: Recurrent Ovarian Cancer
Principal Investigator: Thomas Rutherford |
A Phase 3, Randomized, Open Label Trial of Lenalidomide/Dexamethasone With or Without Elotuzumab in Subjects with Previously Untreated Multiple Myeloma (CA204006)
Disease/Condition: Multiple Myeloma
Principal Investigator: Dhodapkar, Madhav |
A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination with Rituximab-CHOP in Patients with Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL)
Disease/Condition: Advanced Stage Diffuse Large B-Cell Lymphoma
Principal Investigator: Daniel O. Persky |
A Phase I/IIa, First Time in human, open-label dose-escalation study of GSK2636771 in subjects with advanced solid tumors with PTEN deficiency
Disease/Condition: Breast Cancer (ER, PR, and HER2 negative) | Colorectal Cancer | Endometrial Cancer | Gastric Adenocarcinoma | Glioblastoma Multiforme | Head/ Neck Squamous Cell Carcinoma | Melanoma | Non-Small Cell Lung Cancer (NSCLC) | Ovarian Cancer | Prostate Cancer
Principal Investigator: Roy Herbst |
A Phase II Study of Cixutumumab (IMC-A12; IND# 100947) in Combination with Temsirolimus (IND# 61010) in Pediatric Patients with Recurrent or Refractory Solid Tumors (ADVL1221)
Disease/Condition: Recurrent or Refractory Solid Tumors
Principal Investigator: Nina Kadan-Lottick |
A Phase II Trial of Response-Adapted Therapy of Stage III-IV Hodgkin Lymphoma Using Early Interim FDG-PET Imaging
Disease/Condition: Hodgkin Lymphoma
Principal Investigator: Stuart Evan Seropian |
A Phase III Randomized Trial of Chemotherapy with or without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer (ECOG E1305)
Disease/Condition: Head and Neck Cancer
Principal Investigator: Hari Anant Deshpande |
A Pilot Pre-Operative Window Trial of Black Cohosh in Women with Ductal Carcinoma in situ
Disease/Condition: Breast Ductal Carcinoma In Situ (DCIS)
Principal Investigator: Erin Wysong Hofstatter |
A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-cell Lymphoma Patients
Disease/Condition: Anaplastic Large Cell Lymphoma (ALCL) | Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) | Lymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, Peripheral | other transformed T-cell lymphomas
Principal Investigator: Francine M Foss |
A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients using ColoPrint
Disease/Condition: Colon Cancer
Principal Investigator: Vikram Reddy |
A Randomized Controlled Trial of Routine Shave Margins Versus Standard Partial Mastectomy in Breast Cancer Patients
Disease/Condition: Breast Cancer
Principal Investigator: Anees B. Chagpar |
A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Erin Wysong Hofstatter |
A RANDOMIZED, MULTICENTER, ADAPTIVE PHASE II/III STUDY TO EVALUATE THE EFFICACY AND SAFETY OF TRASTUZUMAB EMTANSINE (T-DM1) VERSUS TAXANE (DOCETAXEL OR PACLITAXEL) IN PATIENTS WITH PREVIOUSLY TREATED LOCALLY ADVANCED OR METASTATIC HER2-POSITIVE GASTRIC CANCER, INCLUDING ADENOCARCINOMA OF THE GASTROESOPHAGEAL JUNCTION
Disease/Condition: Adenocarcinoma of the Gastroesophageal Junction | Gastric Cancer
Principal Investigator: Howard S Hochster |
A Randomized, Phase II, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating The Efficacy And Safety Of Onartuzumab (MetMAb) In Combination With 5-Fluorouracil, Folinic Acid, And Oxaliplatin (mFOLFOX6) In Patients With Metastatic HER2-Negative Gastroesophageal Cancer
Disease/Condition: Gastroesophageal Cancer
Principal Investigator: Jill Lacy |
A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Roy Herbst |
A Single-arm, Multicenter, Proof-of-Concept Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects with Elevated Serum Calcium Despite Recent Treatment with IV Bisphosphonates
Disease/Condition: Hypercalcemia
Principal Investigator: Karl L. Insogna |
ACRIN 6690: A Prospective, Multicenter Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast-Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation
Disease/Condition: Liver Cancer
Principal Investigator: Jeffrey C. Weinreb |
An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma (The “ACT IV” Study)
Disease/Condition: Glioblastoma
Principal Investigator: Kevin Patrick Becker |
An Intervention to Improve Outcomes in Patients With Advanced Cancer
Disease/Condition: Cancer
Principal Investigator: Ruth McCorkle, RN, PhD |
An Open Label Assessment of Safety and Efficacy of Ruxolitinib (INCB018424) in Subjects with Primary Myelofibrosis, Post Essential Thromboythemia Myelofibrosis and Post Polycythemia Vera Myelofibrosis Who Have Platelet Counts of 50x109 /L to 100 x 109/L
Disease/Condition: Post Essential Thromboythemia Myelofibrosis | Post Polycythemia Vera Myelofibrosis | Primary Myelofibrosis
Principal Investigator: Nikolai Alexandrovich Podoltsev |
Assessment Tool for Older Patients With Cancer
Disease/Condition: Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Unspecified Adult Solid Tumor, Protocol Specific
Principal Investigator: Gross, Cary P |
BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Roy Herbst |
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Disease/Condition: Neuroblastoma
Principal Investigator: Kupfer, Gary |
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Disease/Condition: Leukemia | Lymphoma
Principal Investigator: Gary Kupfer |
Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia
Disease/Condition: Cognitive/Functional Effects | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment
Principal Investigator: Gary Kupfer |
Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer
Disease/Condition: Endometrial Cancer
Principal Investigator: Masoud Azodi |
Cardiovascular Risk Assessment in Women with Early Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Jessica Marie Coviello |
Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy
Disease/Condition: Fungal Infection | Leukemia | Neutropenia
Principal Investigator: Nina Kadan-Lottick |
Cetuximab and Radiation Therapy in Head and Neck Cancer
Disease/Condition: Head and Neck Cancer
Principal Investigator: Roy Decker |
Characterization of Tumor Cells in the Arterial and Venous Circulations of Non Small Cell Lung Cancer Patients
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Daniel J. Boffa |
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
Disease/Condition: Brain and Central Nervous System Tumors
Principal Investigator: Gary Kupfer |
Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
Disease/Condition: Fallopian Tube Cancer | Ovarian Cancer | Primary Peritoneal Cavity Cancer
Principal Investigator: Thomas J. Rutherford |
Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-Small Lung Cancer That Was Removed By Surgery
Disease/Condition: Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer | Stage IIIA Non-small Cell Lung Cancer
Principal Investigator: Scott Nicholas Gettinger |
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Disease/Condition: Chordoma | Desmoid Tumor | Sarcoma
Principal Investigator: Gary Kupfer |
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
Disease/Condition: Rhabdomyosarcoma
Principal Investigator: Gary Kupfer |
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Disease/Condition: Brain and Central Nervous System Tumors | Kidney Cancer | Sarcoma
Principal Investigator: Gary Kupfer |
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer
Disease/Condition: Liver Cancer
Principal Investigator: Nina Kadan-Lottick |
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Disease/Condition: Contiguous Stage II Adult Lymphoblastic Lymphoma | Noncontiguous Stage II Adult Lymphoblastic Lymphoma | Stage II Adult T-cell Leukemia/Lymphoma | Stage II Childhood Lymphoblastic Lymphoma | Stage III Adult Lymphoblastic Lymphoma | Stage III Adult T-cell Leukemia/Lymphoma | Stage III Childhood Lymphoblastic Lymphoma | Stage IV Adult Lymphoblastic Lymphoma | Stage IV Adult T-cell Leukemia/Lymphoma | Stage IV Childhood Lymphoblastic Lymphoma | T-cell Adult Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia | Untreated Adult Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia
Principal Investigator: Gary Kupfer |
Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
Disease/Condition: Brain and Central Nervous System Tumors
Principal Investigator: Gary Kupfer |
Continuous Versus Intermittent Dosing Regimens for Pomalidomide in Relapsed/Refractory Multiple Myeloma
Disease/Condition: Multiple Myeloma
Principal Investigator: Madhav Dhodapkar, M.D. |
Defibrotide for Patients with Hepatic Veno-Occlusive Disease (VOD): A Treatment IND Study (UNDER CFR 312.34)
Disease/Condition: Hepatic Veno-Occlusive Disease
Principal Investigator: Stuart Evan Seropian |
Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
Disease/Condition: Malignant Melanoma
Principal Investigator: Mario Sznol |
Epidemiology and Genetics of Early Onset Basal Cell Carcinoma
Disease/Condition: Basal Cell Carcinoma
Principal Investigator: Susan T Mayne |
Evaluation of Trastuzumab In Patients With HER2 Positive Persistent Or Recurrent Vulvar Paget's Disease
Disease/Condition: Paget's Disease of the Vulva
Principal Investigator: Thomas J. Rutherford, MD, PhD |
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer
Disease/Condition: Distal Urethral Cancer | Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Proximal Urethral Cancer | Recurrent Bladder Cancer | Recurrent Prostate Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Urethral Cancer | Stage IV Bladder Cancer | Stage IV Prostate Cancer | Transitional Cell Carcinoma of the Bladder | Urethral Cancer Associated With Invasive Bladder Cancer
Principal Investigator: Hari A. Deshpande |
HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer
Disease/Condition: Advanced Breast Cancer
Principal Investigator: Abu-Khalaf, Maysa Mahmoud |
Her2, c-kit EGFR and akt1 Expression in Carcinosarcomas of Female Genital Tract: Prognostic Factors or Potential Markers for Targeted Therapies
Disease/Condition: Gynecological Cancers
Principal Investigator: Ozlen Saglam |
Hormones and Physical Exercise Study
Disease/Condition: Cancer
Principal Investigator: Melinda Liggett Irwin |
Imaging the Effects of R-CHOP and other Anthracycline containing Chemotherapy on Cognitive Function in Patients with high-grade lymphoma
Disease/Condition: Lymphoma
Principal Investigator: Herta H Chao |
Immune Function in T-Cell Lymphoma
Disease/Condition: Lymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, Peripheral
Principal Investigator: Francine M Foss |
Immunology and Pathobiology of Plasma Cell Disorders
Disease/Condition: Plasma cell disorder
Principal Investigator: Madhav V. Dhodapkar |
Impact of Exercise on Ovarian Cancer Prognosis
Disease/Condition: Ovarian Cancer
Principal Investigator: Melinda Liggett Irwin |
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster |
Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma
Disease/Condition: Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma
Principal Investigator: Nina Kadan-Lottick |
Longitudinal Assessment and Functional Outcomes in Patients with Hematologic Malignancies and Related Disorders
Disease/Condition: Hematologic Malignancies
Principal Investigator: Stephanie Halene |
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Disease/Condition: Brain and Central Nervous System Tumors | Chronic Myeloproliferative Disorders | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Lymphoma | Lymphoproliferative Disorder | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic Syndromes | Myelodysplastic/Myeloproliferative Neoplasms | Precancerous Condition | Unspecified Childhood Solid Tumor, Protocol Specific
Principal Investigator: Gary Kupfer |
Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
Disease/Condition: Leukemia
Principal Investigator: Kupfer, Gary |
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
Disease/Condition: Brain and Central Nervous System Tumors
Principal Investigator: Gary Kupfer |
Maintenance Therapy with Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia
Disease/Condition: Chronic Lymphocytic Leukemia
Principal Investigator: Terri Lynn Parker |
Mammosite Breast Brachytherapy Optimization in the Treatment of Breast Carcinoma
Disease/Condition: Breast Neoplasms
Principal Investigator: Weidhaas, Joanne Barnes |
Neuropsychological and Behavioral Testing in Young Patients With Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)
Disease/Condition: Brain and Central Nervous System Tumors | Chemotherapeutic Agent Toxicity | Cognitive/Functional Effects | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment | Radiation Toxicity | Therapy-related Toxicity
Principal Investigator: Gary Kupfer |
Ofatumumab vs. Rituximab Salvage Chemoimmunotherapy followed by ASCT in Relapsed or Refractory DLBCL (ORCHARDD Trial/ Phase III)
Disease/Condition: Diffuse Large B Cell Lymphoma
Principal Investigator: Stuart Evan Seropian |
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster |
Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed Persistent or Recurrent Uterine or Ovarian Cancer
Disease/Condition: Ovarian Cancer | Sarcoma
Principal Investigator: Dan-Arin Silasi |
PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma
Disease/Condition: Limited-stage Diffuse Large B-Cell Lymphoma
Principal Investigator: Daniel O. Persky |
Phase II Study of FOLFIRINOX for Advanced Pancreatic Cancer
Disease/Condition: Advanced Pancreatic Cancer | Metastatic Pancreatic Cancer | Pancreatic Cancer
Principal Investigator: Jill Lacy, MD |
Phase III, Multi-Center, Randomized, Controlled Study to Assess the Efficacy and Safety of ON 01910.Na Administered in a 72-Hour Continuous IV Every Other Week in Myelodysplastic Syndrome Patients with Excess Blasts Relapsing After, or Refractory to, or Intolerant to Azacitidine or Decitabine.
Disease/Condition: Myelodysplastic Syndromes
Principal Investigator: Nikolai Alexandrovich Podoltsev |
Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients with Advanced Breast and Gastrointestinal Tumors
Disease/Condition: Gastrointestinal Tumors | Metastatic Breast Cancer
Principal Investigator: Gina G Chung |
Radiation Therapy in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Weidhaas, Joanne Barnes |
Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer
Disease/Condition: Head and Neck Cancer
Principal Investigator: Daniel Morgensztern |
Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer
Disease/Condition: Adenocarcinoma of the Esophagus | Adenocarcinoma of the Gastroesophageal Junction | Stage IB Esophageal Cancer | Stage IIA Esophageal Cancer | Stage IIB Esophageal Cancer | Stage IIIA Esophageal Cancer | Stage IIIB Esophageal Cancer
Principal Investigator: Bryan William Chang |
Randomized Double-Blind, Phase III Study of TAS-102 plus Best Supportive Care (BSC) Versus Placebo Plus Best Supportive Care in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapies
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster |
Randomized, double-blind, Phase II Study of FOLFOX/Bevacizumab with MetMAb versus Placebo as First-Line Treatment for Patients with Metastatic Colorectal Cancer
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster |
Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia
Disease/Condition: Leukemia
Principal Investigator: Gary Kupfer |
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Disease/Condition: Leukemia
Principal Investigator: Nina Kadan-Lottick |
Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD
Disease/Condition: Graft Versus Host Disease | Leukemia | Myelodysplastic Syndromes
Principal Investigator: Warren Shlomchik, MD |
Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Disease/Condition: Adult Primary Hepatocellular Carcinoma | Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer
Principal Investigator: Stacey M Stein |
Study of Blood Samples From Newborns With Down Syndrome
Disease/Condition: Down Syndrome | Leukemia
Principal Investigator: Nina Kadan-Lottick |
Study of Kidney Tumors in Young Patients
Disease/Condition: Kidney Cancer | Nonneoplastic Condition
Principal Investigator: Gary Kupfer |
Study of Late-Occurring Complications in Childhood Cancer Survivors
Disease/Condition: Cancer
Principal Investigator: Kupfer, Gary |
Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Erin Wysong Hofstatter |
Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Metastatic Childhood Soft Tissue Sarcoma | Previously Untreated Childhood Rhabdomyosarcoma | Stage IV Adult Soft Tissue Sarcoma
Principal Investigator: Nina Kadan-Lottick |
Testing the Feasibility of a Nurse Patient Navigation Intervention in Lung Cancer
Disease/Condition: Lung Cancer
Principal Investigator: Ruth McCorkle |
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms Tumor
Disease/Condition: Kidney Cancer
Principal Investigator: Kupfer, Gary |
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Mixed Childhood Rhabdomyosarcoma | Pleomorphic Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Childhood Rhabdomyosarcoma
Principal Investigator: Nina Kadan-Lottick |
Women With Cancer: An Exercise Study to Promote Health
Disease/Condition: Bone Loss | Cancer
Principal Investigator: M. Tish Knobf, PhD |
Women's Experience with Triple Negative Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Yasemin Turkman |
