Cancer Signaling Networks Recent Publications
2024
- Optimal conditions for carrying out trypsin digestions on complex proteomes: From bulk samples to single cells.Mansuri MS, Bathla S, Lam TT, Nairn AC, Williams KR. J Proteomics. 2024 Apr 15; 2024 Feb 5. PMID: 38325732.
- Precision Oncology in Gastrointestinal and Colorectal Cancer Surgery.McDonald HG, Kerekes DM, Kim J, Khan SA. Surg Oncol Clin N Am. 2024 Apr; 2024 Jan 9. PMID: 38401913.
- Calcium flow at ER-TGN contact sites facilitates secretory cargo export.Ramazanov BR, Parchure A, Di Martino R, Kumar A, Chung M, Kim Y, Griesbeck O, Schwartz MA, Luini A, von Blume J. Mol Biol Cell. 2024 Apr 1; 2024 Jan 31. PMID: 38294859.
- Skeletal muscle TET3 promotes insulin resistance through destabilisation of PGC-1α.Liu B, Xie D, Huang X, Jin S, Dai Y, Sun X, Li D, Bennett AM, Diano S, Huang Y. Diabetologia. 2024 Apr; 2024 Jan 13. PMID: 38216792.
- The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy.Pierpont EI, Bennett AM, Schoyer L, Stronach B, Anschutz A, Borrie SC, Briggs B, Burkitt-Wright E, Castel P, Cirstea IC, Draaisma F, Ellis M, Fear VS, Frone MN, Flex E, Gelb BD, Green T, Gripp KW, Khoshkhoo S, Kieran MW, Kleemann K, Klein-Tasman BP, Kontaridis MI, Kruszka P, Leoni C, Liu CZ, Merchant N, Magoulas PL, Moertel C, Prada CE, Rauen KA, Roelofs R, Rossignol R, Sevilla C, Sevilla G, Sheedy R, Stieglitz E, Sun D, Tiemens D, White F, Wingbermühle E, Wolf C, Zenker M, Andelfinger G. Am J Med Genet A. 2024 Apr; 2023 Nov 15. PMID: 37969032.
- Hearing loss promotes Alzheimer's disease.Zhao HB, Yang Y. Nat Aging. 2024 Mar 15; 2024 Mar 15. PMID: 38491290.
- MLL1 regulates cytokine-driven cell migration and metastasis.Nair PR, Danilova L, Gómez-de-Mariscal E, Kim D, Fan R, Muñoz-Barrutia A, Fertig EJ, Wirtz D. Sci Adv. 2024 Mar 15; 2024 Mar 13. PMID: 38478601.
- Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis.Luan Y, Hu J, Wang Q, Wang X, Li W, Qu R, Yang C, Rajendran BK, Zhou H, Liu P, Zhang N, Shi Y, Liu Y, Tang W, Lu J, Wu D. Cell Rep. 2024 Mar 8; 2024 Mar 8. PMID: 38461416.
- microRNA-33 controls hunger signaling in hypothalamic AgRP neurons.Price NL, Fernández-Tussy P, Varela L, Cardelo MP, Shanabrough M, Aryal B, de Cabo R, Suárez Y, Horvath TL, Fernández-Hernando C. Nat Commun. 2024 Mar 8; 2024 Mar 8. PMID: 38459068.
- Author Correction: Subclonal cooperation drives metastasis by modulating local and systemic immune microenvironments.Janiszewska M, Tabassum DP, Castaño Z, Cristea S, Yamamoto KN, Kingston NL, Murphy KC, Shu S, Harper NW, Del Alcazar CG, Alečković M, Ekram MB, Cohen O, Kwak M, Qin Y, Laszewski T, Luoma A, Marusyk A, Wucherpfennig KW, Wagle N, Fan R, Michor F, McAllister SS, Polyak K. Nat Cell Biol. 2024 Mar 5; 2024 Mar 5. PMID: 38443568.
- Providing 0.1 Full-Time Equivalent (FTE) Support to Fellowship Core Faculty Improves Faculty Involvement in Fellowship Education and Recruitment.Butt A, Christian J, Kress A, Lu BY, Hurwitz ME, Goldberg SB, Podoltsev NA, Gilkes L, Lee AI. J Cancer Educ. 2024 Mar 2; 2024 Mar 2. PMID: 38430454.
- The art of observation: bridging science and art to see the unexpected.Gonzalez LE, Wei H, Greco V, Friedlaender LK. Development. 2024 Mar 1; 2024 Mar 13. PMID: 38477686.
- A New Mitochondrial Uncoupler Improves Metabolic Homeostasis in Mice.Ramshankar G, Perry RJ. Diabetes. 2024 Mar 1. PMID: 38377448.
- Novel muscle-derived extracellular matrix hydrogel promotes angiogenesis and neurogenesis in volumetric muscle loss.Chen Z, Huang Y, Xing H, Tseng T, Edelman H, Perry R, Kyriakides TR. Matrix Biol. 2024 Mar; 2024 Feb 6. PMID: 38325441.
- Metabolic underpinnings of cancer-related fatigue.Zhang X, Perry RJ. Am J Physiol Endocrinol Metab. 2024 Mar 1; 2024 Jan 31. PMID: 38294698.
- Thiazolidinedione enhances the efficacy of anti-PD-1 monoclonal antibody in murine melanoma.Zhang X, Gao Y, Tang K, Li Z, Halberstam AA, Zhou L, Perry RJ. Am J Physiol Endocrinol Metab. 2024 Mar 1; 2024 Jan 31. PMID: 38294697.
- Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer.Jahangir CA, Page DB, Broeckx G, Gonzalez CA, Burke C, Murphy C, Reis-Filho JS, Ly A, Harms PW, Gupta RR, Vieth M, Hida AI, Kahila M, Kos Z, van Diest PJ, Verbandt S, Thagaard J, Khiroya R, Abduljabbar K, Acosta Haab G, Acs B, Adams S, Almeida JS, Alvarado-Cabrero I, Azmoudeh-Ardalan F, Badve S, Baharun NB, Bellolio ER, Bheemaraju V, Blenman KR, Botinelly Mendonça Fujimoto L, Burgues O, Chardas A, Cheang MCU, Ciompi F, Cooper LA, Coosemans A, Corredor G, Dantas Portela FL, Deman F, Demaria S, Dudgeon SN, Elghazawy M, Fernandez-Martín C, Fineberg S, Fox SB, Giltnane JM, Gnjatic S, Gonzalez-Ericsson PI, Grigoriadis A, Halama N, Hanna MG, Harbhajanka A, Hart SN, Hartman J, Hewitt S, Horlings HM, Husain Z, Irshad S, Janssen EA, Kataoka TR, Kawaguchi K, Khramtsov AI, Kiraz U, Kirtani P, Kodach LL, Korski K, Akturk G, Scott E, Kovács A, Laenkholm AV, Lang-Schwarz C, Larsimont D, Lennerz JK, Lerousseau M, Li X, Madabhushi A, Maley SK, Manur Narasimhamurthy V, Marks DK, McDonald ES, Mehrotra R, Michiels S, Kharidehal D, Minhas FUAA, Mittal S, Moore DA, Mushtaq S, Nighat H, Papathomas T, Penault-Llorca F, Perera RD, Pinard CJ, Pinto-Cardenas JC, Pruneri G, Pusztai L, Rajpoot NM, Rapoport BL, Rau TT, Ribeiro JM, Rimm D, Vincent-Salomon A, Saltz J, Sayed S, Hytopoulos E, Mahon S, Siziopikou KP, Sotiriou C, Stenzinger A, Sughayer MA, Sur D, Symmans F, Tanaka S, Taxter T, Tejpar S, Teuwen J, Thompson EA, Tramm T, Tran WT, van der Laak J, Verghese GE, Viale G, Wahab N, Walter T, Waumans Y, Wen HY, Yang W, Yuan Y, Bartlett J, Loibl S, Denkert C, Savas P, Loi S, Specht Stovgaard E, Salgado R, Gallagher WM, Rahman A. J Pathol. 2024 Mar; 2024 Jan 17. PMID: 38230434.
- Meeting Report on the 3rd Chinese American Society for Mass Spectrometry Conference-Advancing Biological and Pharmaceutical Mass Spectrometry.Chen H, Fu Y, Han M, Han X, Hao L, Huan T, Huang L, Huang M, Ji Q, Jiang T, Jiang Y, Li L, Li L, Liang X, Lih M, Lin Y, Liu X, Liu T, Liu Y, Ma S, Peng J, Qi YA, Qu J, Shou W, Sun L, Wang M, Wang S, Wu R, Wu S, Yan X, Yang J, Yang W, Yang Z, Yu Y, Zhang H, Zhang H, Zhao S, Zhu J, Zhu Y, Wang Y, Weng N. Biomed Chromatogr. 2024 Mar; 2023 Dec 10. PMID: 38071756.
- A plain language summary exploring a new treatment combination for untreated locally advanced or metastatic urothelial cancer: enfortumab vedotin plus pembrolizumab.Hoimes CJ, Flaig TW, Milowsky MI, Friedlander TW, Bilen MA, Gupta S, Srinivas S, Merchan JR, McKay RR, Petrylak DP, Sasse C, Moreno BH, Yu Y, Carret AS, Rosenberg JE. Future Oncol. 2024 Mar; 2023 Nov 23. PMID: 37994649.
- Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.Rosenberg JE, Mamtani R, Sonpavde GP, Loriot Y, Duran I, Lee JL, Matsubara N, Vulsteke C, Castellano D, Sridhar SS, Pappot H, Gurney H, Bedke J, van der Heijden MS, Galli L, Keam B, Masumori N, Meran J, O'Donnell PH, Park SH, Grande E, Sengeløv L, Uemura H, Skaltsa K, Campbell M, Matsangou M, Wu C, Hepp Z, McKay C, Powles T, Petrylak DP. Eur Urol. 2024 Feb 27; 2024 Feb 27. PMID: 38418343.
- Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma.Kim IK, Diamond MS, Yuan S, Kemp SB, Kahn BM, Li Q, Lin JH, Li J, Norgard RJ, Thomas SK, Merolle M, Katsuda T, Tobias JW, Baslan T, Politi K, Vonderheide RH, Stanger BZ. Nat Commun. 2024 Feb 20; 2024 Feb 20. PMID: 38378697.
- Spatial-temporal order-disorder transition in angiogenic NOTCH signaling controls cell fate specification.Kang TY, Bocci F, Nie Q, Onuchic JN, Levchenko A. Elife. 2024 Feb 20; 2024 Feb 20. PMID: 38376371.
- Effect of Burosumab on Muscle Function and Strength, and Rates of ATP Synthesis in Skeletal Muscle in Adults With XLH.Insogna KL, Sullivan R, Parziale S, Deng Y, Carrano D, Simpson C, Dufour S, Carpenter T, Petersen KF. J Clin Endocrinol Metab. 2024 Feb 20. PMID: 37930769.
- Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail.Sexton JA, Potchernikov T, Bibeau JP, Casanova-Sepúlveda G, Cao W, Lou HJ, Boggon TJ, De La Cruz EM, Turk BE. Nat Commun. 2024 Feb 16; 2024 Feb 16. PMID: 38365893.
- ASCL1 Drives Tolerance to Osimertinib in EGFR Mutant Lung Cancer in Permissive Cellular Contexts.Hu B, Wiesehöfer M, de Miguel FJ, Liu Z, Chan LH, Choi J, Melnick MA, Arnal-Estape A, Walther Z, Zhao D, Lopez-Giraldez F, Wurtz A, Cai G, Fan R, Gettinger S, Xiao A, Yan Q, Homer R, Nguyen DX, Politi K. Cancer Res. 2024 Feb 15; 2024 Feb 15. PMID: 38359163.
- Microbiome Depletion Increases Fentanyl Self-Administration and Alters the Striatal Proteome Through Short-Chain Fatty Acids.Hofford RS, Meckel KR, Wiser EJ, Wang W, Sens JP, Kim M, Godino A, Lam TT, Kiraly DD. eNeuro. 2024 Feb; 2024 Feb 15. PMID: 38164564.
- Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis.Shi X, DeCiucis M, Grabinska KA, Kanyo J, Liu A, Lam TT, Shen H. Mol Cell. 2024 Feb 15; 2023 Dec 28. PMID: 38157846.
- DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time.Relovska S, Wang H, Zhang X, Fernández-Tussy P, Jeong KJ, Choi J, Suárez Y, McDonald JG, Fernández-Hernando C, Chung JJ. bioRxiv. 2024 Feb 11; 2024 Feb 11. PMID: 38187697.
- Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage.Ruz-Maldonado I, Gonzalez JT, Zhang H, Sun J, Bort A, Kabir I, Kibbey RG, Suárez Y, Greif DM, Fernández-Hernando C. Nat Commun. 2024 Feb 10; 2024 Feb 10. PMID: 38341404.
- Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues.Bai Z, Zhang D, Gao Y, Tao B, Bao S, Enninful A, Zhang D, Su G, Tian X, Zhang N, Xiao Y, Liu Y, Gerstein M, Li M, Xing Y, Lu J, Xu ML, Fan R. bioRxiv. 2024 Feb 8; 2024 Feb 8. PMID: 38370833.
- Rapidly progressive subungual gray-brown melanonychia.Echeandia-Francis C, Nock MR, Myung P, Zubek AE. JAAD Case Rep. 2024 Feb; 2024 Jan 28. PMID: 38414828.
- Circulating Tumor DNA Dynamics Fail to Predict Efficacy of Poly(ADP-ribose) Polymerase/VEGFR Inhibition in Patients With Heavily Pretreated Advanced Solid Tumors.Hu Y, Narayan A, Xu Y, Wolfe J, Vu D, Trinh T, Kantak C, Ivy SP, Eder JP, Deng Y, LoRusso P, Kim JW, Patel AA. JCO Precis Oncol. 2024 Feb. PMID: 38412387.
- Hepatocyte-specific mitogen-activated protein kinase phosphatase 1 in sexual dimorphism and susceptibility to alcohol induced liver injury.Walter MN, Montoya-Durango D, Rodriguez W, Wang Y, Zhang J, Chariker JH, Rouchka EC, Maldonado C, Bennett A, McClain CJ, Barve S, Gobejishvili L. Front Immunol. 2024; 2024 Feb 1. PMID: 38370409.
- Correlation of HER2 Protein Level With mRNA Level Quantified by RNAscope in Breast Cancer.Li X, Lee JH, Gao Y, Zhang J, Bates KM, Rimm DL, Zhang H, Smith GH, Lawson D, Meisel J, Chang J, Huo L. Mod Pathol. 2024 Feb; 2023 Dec 20. PMID: 38135153.
- Application of a 3D bioprinter: jet technology for 'biopatch' development using cells on hydrogel supports.DeMel DC, Wagner GA, Maresca JA, Geibel JP. Biotechniques. 2024 Feb; 2023 Dec 12. PMID: 38084384.
- Response to commentary to Heresy - Is there a role for ultrasound in management of the non palpable testicle?Weiss RM. J Pediatr Urol. 2024 Feb; 2023 Nov 4. PMID: 37968163.
- Biallelic CRELD1 variants cause a multisystem syndrome, including neurodevelopmental phenotypes, cardiac dysrhythmias, and frequent infections.Jeffries L, Mis EK, McWalter K, Donkervoort S, Brodsky NN, Carpier JM, Ji W, Ionita C, Roy B, Morrow JS, Darbinyan A, Iyer K, Aul RB, Banka S, Chao KR, Cobbold L, Cohen S, Custodio HM, Drummond-Borg M, Elmslie F, Finanger E, Hainline BE, Helbig I, Hewson S, Hu Y, Jackson A, Josifova D, Konstantino M, Leach ME, Mak B, McCormick D, McGee E, Nelson S, Nguyen J, Nugent K, Ortega L, Goodkin HP, Roeder E, Roy S, Sapp K, Saade D, Sisodiya SM, Stals K, Towner S, Wilson W, Khokha MK, Bönnemann CG, Lucas CL, Lakhani SA. Genet Med. 2024 Feb; 2023 Nov 7. PMID: 37947183.
- Co-Occurring Alterations in Multiple Tumor Suppressor Genes Are Associated With Worse Outcomes in Patients With EGFR-Mutant Lung Cancer.Stockhammer P, Grant M, Wurtz A, Foggetti G, Expósito F, Gu J, Zhao H, Choi J, Chung S, Li F, Walther Z, Dietz J, Duffield E, Gettinger S, Politi K, Goldberg SB. J Thorac Oncol. 2024 Feb; 2023 Oct 6. PMID: 37806385.
- Heresy - Is there a role for ultrasound in management of the non-palpable testicle?Press BH, Olawoyin O, Arlen AM, Silva CT, Weiss RM. J Pediatr Urol. 2024 Feb; 2023 Sep 9. PMID: 37749009.
- Avelumab First-line Maintenance for Advanced Urothelial Carcinoma: Analysis from JAVELIN Bladder 100 by Duration of First-line Chemotherapy and Interval Before Maintenance.Sridhar SS, Powles T, Climent Durán MÁ, Park SH, Massari F, Thiery-Vuillemin A, Valderrama BP, Ullén A, Tsuchiya N, Aragon-Ching JB, Gupta S, Petrylak DP, Bellmunt J, Wang J, Laliberte RJ, di Pietro A, Costa N, Grivas P, Sternberg CN, Loriot Y. Eur Urol. 2024 Feb; 2023 Sep 14. PMID: 37714742.
- TREM2 function in glioblastoma immune microenvironment: can we distinguish reality from illusion?Ghosh S, Rothlin CV. Neuro Oncol. 2024 Jan 30; 2024 Jan 30. PMID: 38290471.
- Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations.Habowski AN, Budagavi DP, Scherer SD, Aurora AB, Caligiuri G, Flynn WF, Langer EM, Brody JR, Sears RC, Foggetti G, Arnal Estape A, Nguyen DX, Politi KA, Shen X, Hsu DS, Peehl DM, Kurhanewicz J, Sriram R, Suarez M, Xiao S, Du Y, Li XN, Navone NM, Labanca E, Willey CD. Cancers (Basel). 2024 Jan 29; 2024 Jan 29. PMID: 38339316.
- EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth.Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna RS, Traina KA, Robles-Oteíza C, Ayeni D, Kwong EM, Levy S, Globig AM, Nobari MM, Cheng GZ, Leibel SL, Homer RJ, Shaw RJ, Metallo CM, Politi K, Kaech SM. Cancer Discov. 2024 Jan 25; 2024 Jan 25. PMID: 38270272.
- Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1.Breckel CA, Johnson ZM, Hickey CM, Hochstrasser M. Sci Rep. 2024 Jan 24; 2024 Jan 24. PMID: 38267508.
- Sacituzumab Govitecan in Combination With Pembrolizumab for Patients With Metastatic Urothelial Cancer That Progressed After Platinum-Based Chemotherapy: TROPHY-U-01 Cohort 3.Grivas P, Pouessel D, Park CH, Barthelemy P, Bupathi M, Petrylak DP, Agarwal N, Gupta S, Fléchon A, Ramamurthy C, Davis NB, Recio-Boiles A, Sternberg CN, Bhatia A, Pichardo C, Sierecki M, Tonelli J, Zhou H, Tagawa ST, Loriot Y. J Clin Oncol. 2024 Jan 23; 2024 Jan 23. PMID: 38261969.
- Distinct interactions stabilize EGFR dimers and higher-order oligomers in cell membranes.Mudumbi KC, Burns EA, Schodt DJ, Petrova ZO, Kiyatkin A, Kim LW, Mangiacapre EM, Ortiz-Caraveo I, Rivera Ortiz H, Hu C, Ashtekar KD, Lidke KA, Lidke DS, Lemmon MA. Cell Rep. 2024 Jan 23; 2023 Dec 20. PMID: 38117650.
- Gamma protocadherins in vascular endothelial cells inhibit Klf2/4 to promote atherosclerosis.Joshi D, Coon BG, Chakraborty R, Deng H, Fernandez-Tussy P, Meredith E, Traylor JG Jr, Orr AW, Fernandez-Hernando C, Schwartz MA. bioRxiv. 2024 Jan 21; 2024 Jan 21. PMID: 38293157.
- An unconventional regulatory circuitry involving Aurora B controls anaphase onset and error-free chromosome segregation in trypanosomes.Ballmer D, Lou HJ, Ishii M, Turk BE, Akiyoshi B. bioRxiv. 2024 Jan 20; 2024 Jan 20. PMID: 38293145.
- The CUL5 E3 ligase complex negatively regulates central signaling pathways in CD8(+) T cells.Liao X, Li W, Zhou H, Rajendran BK, Li A, Ren J, Luan Y, Calderwood DA, Turk B, Tang W, Liu Y, Wu D. Nat Commun. 2024 Jan 19; 2024 Jan 19. PMID: 38242867.
- EGFR-driven lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth.Kuhlmann-Hogan A, Cordes T, Xu Z, Kuna RS, Traina KA, Robles-Oteiza C, Ayeni D, Kwong EM, Levy S, Globig AM, Nobari MM, Cheng GZ, Leibel SL, Homer RJ, Shaw RJ, Metallo CM, Politi K, Kaech SM. Cancer Discov. 2024 Jan 19; 2024 Jan 19. PMID: 38241033.
- Experimental and phylogenetic evidence for correlated gene expression evolution in endometrial and skin fibroblasts.Dighe A, Maziarz J, Ibrahim-Hashim A, Gatenby RA, Kshitiz, Levchenko A, Wagner GP. iScience. 2024 Jan 19; 2023 Nov 29. PMID: 38174318.
- Antitumor efficacy of a sequence-specific DNA-targeted γPNA-based c-Myc inhibitor.Malik S, Pradeep SP, Kumar V, Xiao Y, Deng Y, Fan R, Vasquez JC, Singh V, Bahal R. Cell Rep Med. 2024 Jan 16; 2024 Jan 5. PMID: 38183981.
- High-Plex Assessment of Biomarkers in Tumors.Aung TN, Bates KM, Rimm DL. Mod Pathol. 2024 Jan 12; 2024 Jan 12. PMID: 38219953.
- Patient-Reported Outcomes in Patients With Advanced Urothelial Cancer Who Are Ineligible for Cisplatin and Treated With First-Line Enfortumab Vedotin Alone or With Pembrolizumab.Milowsky MI, O'Donnell PH, Hoimes CJ, Petrylak DP, Flaig TW, Moon HH, Friedlander TW, Mar N, McKay RR, Srinivas S, Gravis G, Ramamurthy C, Bupathi M, Bracarda S, Wright P, Hepp Z, Carret AS, Yu Y, Dillon R, Kataria R, Beaumont JL, Purnajo I, Rosenberg JE. J Clin Oncol. 2024 Jan 12; 2024 Jan 12. PMID: 38215355.
- Intracellular calcium links milk stasis to lysosome-dependent cell death during early mammary gland involution.Jeong J, Lee J, Talaia G, Kim W, Song J, Hong J, Yoo K, Gonzalez DG, Athonvarangkul D, Shin J, Dann P, Haberman AM, Kim LK, Ferguson SM, Choi J, Wysolmerski J. Cell Mol Life Sci. 2024 Jan 12; 2024 Jan 12. PMID: 38212474.
- Organ Boundary Circuits Regulate Sox9+ Alveolar Tuft Cells During Post-Pneumonectomy Lung Regeneration.Obata T, Mizoguchi S, Greaney AM, Adams T, Yuan Y, Edelstein S, Leiby KL, Rivero R, Wang N, Kim H, Yang J, Schupp JC, Stitelman D, Tsuchiya T, Levchenko A, Kaminski N, Niklason LE, Brickman Raredon MS. bioRxiv. 2024 Jan 8; 2024 Jan 8. PMID: 38260691.
- The SysteMHC Atlas v2.0, an updated resource for mass spectrometry-based immunopeptidomics.Huang X, Gan Z, Cui H, Lan T, Liu Y, Caron E, Shao W. Nucleic Acids Res. 2024 Jan 5. PMID: 38000392.
- Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients with Metastatic Urothelial Carcinoma.Petrylak DP, Eigl BJ, George S, Heath EI, Hotte SJ, Chism DD, Nabell LM, Picus J, Cheng SY, Appleman LJ, Sonpavde GP, Morgans AK, Pourhosseini P, Wu R, Standley L, Croitoru R, Yu EY. Clin Cancer Res. 2024 Jan 5. PMID: 37861407.
- Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies.Liu Q, Zhang J, Guo C, Wang M, Wang C, Yan Y, Sun L, Wang D, Zhang L, Yu H, Hou L, Wu C, Zhu Y, Jiang G, Zhu H, Zhou Y, Fang S, Zhang T, Hu L, Li J, Liu Y, Zhang H, Zhang B, Ding L, Robles AI, Rodriguez H, Gao D, Ji H, Zhou H, Zhang P. Cell. 2024 Jan 4. PMID: 38181741.
- Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. J Clin Invest. 2024 Jan 4; 2024 Jan 4. PMID: 38175710.
- Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors.Johnston AC, Alicea GM, Lee CC, Patel PV, Hanna EA, Vaz E, Forjaz A, Wan Z, Nair PR, Lim Y, Chen T, Du W, Kim D, Nichakawade TD, Rebecca VW, Bonifant CL, Fan R, Kiemen AL, Wu PH, Wirtz D. bioRxiv. 2024 Jan 4; 2024 Jan 4. PMID: 38168186.
- A kidney-hypothalamus axis promotes compensatory glucose production in response to glycosuria.Faniyan TS, Zhang X, Morgan DA, Robles J, Bathina S, Brookes PS, Rahmouni K, Perry RJ, Chhabra KH. bioRxiv. 2024 Jan 4; 2024 Jan 4. PMID: 37790458.
- Identification of Protein Tyrosine Phosphatase (PTP) Substrates.Perla S, Qiu B, Dorry S, Yi JS, Bennett AM. Methods Mol Biol. 2024. PMID: 38147212.
- Double-take: SARS-CoV-2 has evolved to evade human innate immunity, twice.Foxman EF. Trends Immunol. 2024 Jan; 2023 Dec 24. PMID: 38143224.
- Go for Broke!Yu JB, Kim JW. Int J Radiat Oncol Biol Phys. 2024 Jan 1. PMID: 38049219.
- Automated scoring of tumor-infiltrating lymphocytes informs risk of death from thin melanoma: A nested case-case study.Tan SX, Aung TN, Claeson M, Acs B, Zhou C, Brown S, Lambie D, Baade PD, Pandeya N, Soyer HP, Smithers BM, Whiteman DC, Rimm DL, Khosrotehrani K. J Am Acad Dermatol. 2024 Jan; 2023 Sep 19. PMID: 37730017.
2023
- Apoptosis recognition receptors regulate skin tissue repair in mice.Justynski O, Bridges K, Krause W, Forni MF, Phan QM, Sandoval-Schaefer T, Carter K, King DE, Hsia HC, Gazes MI, Vyce SD, Driskell RR, Miller-Jensen K, Horsley V. Elife. 2023 Dec 21; 2023 Dec 21. PMID: 38127424.
- Autoregulation of the LIM kinases by their PDZ domain.Casanova-Sepúlveda G, Sexton JA, Turk BE, Boggon TJ. Nat Commun. 2023 Dec 19; 2023 Dec 19. PMID: 38114480.
- Mass spectrometry in cerebrospinal fluid uncovers association of glycolysis biomarkers with Alzheimer's disease in a large clinical sample.de Geus MB, Leslie SN, Lam T, Wang W, Roux-Dalvai F, Droit A, Kivisakk P, Nairn AC, Arnold SE, Carlyle BC. Sci Rep. 2023 Dec 16; 2023 Dec 16. PMID: 38104170.
- CLINICAL PREDICTIVE VALUE OF RENALASE IN POST-ERCP PANCREATITIS.Muniraj T, Desir G, Gorelick FS, Guo X, Ciarleglio M, Deng Y, Jamidar PA, Farrell JJ, Aslanian HR, Laine L. Gastrointest Endosc. 2023 Dec 14; 2023 Dec 14. PMID: 38103747.
- APOBEC-1 deletion enhances cisplatin-induced acute kidney injury.Guo X, Blanc V, Davidson NO, Velazquez H, Chen TM, Moledina DG, Moeckel GW, Safirstein RL, Desir GV. Sci Rep. 2023 Dec 14; 2023 Dec 14. PMID: 38097707.
- Automating General Movements Assessment with quantitative deep learning to facilitate early screening of cerebral palsy.Gao Q, Yao S, Tian Y, Zhang C, Zhao T, Wu D, Yu G, Lu H. Nat Commun. 2023 Dec 14; 2023 Dec 14. PMID: 38097602.
- Broad H3K4me3 Domain Is Associated with Spatial Coherence during Mammalian Embryonic Development.Cao X, Ma T, Fan R, Yuan GC. bioRxiv. 2023 Dec 12; 2023 Dec 12. PMID: 38168252.
- Suppression of angiopoietin-like 4 reprograms endothelial cell metabolism and inhibits angiogenesis.Chaube B, Citrin KM, Sahraei M, Singh AK, de Urturi DS, Ding W, Pierce RW, Raaisa R, Cardone R, Kibbey R, Fernández-Hernando C, Suárez Y. Nat Commun. 2023 Dec 12; 2023 Dec 12. PMID: 38086791.
- Master Transcription Factor Reprogramming Unleashes Selective Translation Promoting Castration Resistance and Immune Evasion in Lethal Prostate Cancer.Santasusagna S, Zhu S, Jawalagatti V, Carceles-Cordon M, Ertel A, Garcia-Longarte S, Song WM, Fujiwara N, Li P, Mendizabal I, Petrylak DP, Kelly WK, Reddy EP, Wang L, Schiewer MJ, Lujambio A, Karnes J, Knudsen KE, Cordon-Cardo C, Dong H, Huang H, Carracedo A, Hoshida Y, Rodriguez-Bravo V, Domingo-Domenech J. Cancer Discov. 2023 Dec 12. PMID: 37676710.
- A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell-cell contacts.Johnson B, Iuliano M, Lam T, Biederer T, De Camilli P. bioRxiv. 2023 Dec 6; 2023 Dec 6. PMID: 38106008.
- Safety and efficacy of immune checkpoint inhibitors in advanced penile cancer: report from the Global Society of Rare Genitourinary Tumors.El Zarif T, Nassar AH, Pond GR, Zhuang TZ, Master V, Nazha B, Niglio S, Simon N, Hahn AW, Pettaway CA, Tu SM, Abdel-Wahab N, Velev M, Flippot R, Buti S, Maruzzo M, Mittra A, Gheeya J, Yang Y, Rodriguez PA, Castellano D, de Velasco G, Roviello G, Antonuzzo L, McKay RR, Vincenzi B, Cortellini A, Hui G, Drakaki A, Glover M, Khaki AR, El-Am E, Adra N, Mouhieddine TH, Patel V, Piedra A, Gernone A, Davis NB, Matthews H, Harrison MR, Kanesvaran R, Giudice GC, Barata P, Farolfi A, Lee JL, Milowsky MI, Stahlfeld C, Appleman L, Kim JW, Freeman D, Choueiri TK, Spiess PE, Necchi A, Apolo AB, Sonpavde GP. J Natl Cancer Inst. 2023 Dec 6. PMID: 37563779.
- Intracellular tension sensor reveals mechanical anisotropy of the actin cytoskeleton.Amiri S, Muresan C, Shang X, Huet-Calderwood C, Schwartz MA, Calderwood DA, Murrell M. Nat Commun. 2023 Dec 4; 2023 Dec 4. PMID: 38049429.
- A medical multimodal large language model for future pandemics.Liu F, Zhu T, Wu X, Yang B, You C, Wang C, Lu L, Liu Z, Zheng Y, Sun X, Yang Y, Clifton L, Clifton DA. NPJ Digit Med. 2023 Dec 2; 2023 Dec 2. PMID: 38042919.
- Natural isoaspartyl protein modification of ZAP70 alters T cell responses in lupus.Yang ML, Lam TT, Kanyo J, Kang I, Zhou ZS, Clarke SG, Mamula MJ. Autoimmunity. 2023 Dec; 2023 Nov 23. PMID: 37994408.
- The New NCI Precision Medicine Trials.Harris LN, Blanke CD, Erba HP, Ford JM, Gray RJ, LeBlanc ML, Hu-Lieskovan S, Litzow MR, Luger SM, Meric-Bernstam F, O'Dwyer PJ, Othus MKD, Politi K, Shepherd LE, Allegra CJ, Chen HX, Ivy SP, Korde LA, Little RF, McShane LM, Moscow JA, Patton DR, Thurin M, Yee LM, Doroshow JH. Clin Cancer Res. 2023 Dec 1. PMID: 37531248.
- An Assessment of the Therapeutic Landscape for the Treatment of Heart Disease in the RASopathies.Yi JS, Perla S, Bennett AM. Cardiovasc Drugs Ther. 2023 Dec; 2022 Feb 14. PMID: 35156148.
- Linear motif specificity in signaling through p38α and ERK2 mitogen-activated protein kinases.Torres Robles J, Lou HJ, Shi G, Pan PL, Turk BE. Proc Natl Acad Sci U S A. 2023 Nov 28; 2023 Nov 21. PMID: 37988460.
- Sis2 regulates yeast replicative lifespan in a dose-dependent manner.Ölmez TT, Moreno DF, Liu P, Johnson ZM, McGinnis MM, Tu BP, Hochstrasser M, Acar M. Nat Commun. 2023 Nov 27; 2023 Nov 27. PMID: 38012152.
- Common Pathways of Epileptogenesis in Patients With Epilepsy Post-Brain Injury: Findings From a Systematic Review and Meta-analysis.Misra S, Khan EI, Lam TT, Mazumder R, Gururangan K, Hickman LB, Goswami V, Funaro MC, Eldem E, Sansing LH, Sico JJ, Quinn TJ, Liebeskind DS, Montaner J, Kwan P, Mishra NK. Neurology. 2023 Nov 27; 2023 Nov 27. PMID: 37550071.
- Emerging Prognostic and Predictive Significance of Stress Keratin 17 in HPV-Associated and Non HPV-Associated Human Cancers: A Scoping Review.Lozar T, Wang W, Gavrielatou N, Christensen L, Lambert PF, Harari PM, Rimm DL, Burtness B, Grasic Kuhar C, Carchman EH. Viruses. 2023 Nov 25; 2023 Nov 25. PMID: 38140561.
- Single-Cell Measurements and Modeling and Computation of Decision-Making Errors in a Molecular Signaling System with Two Output Molecules.Emadi A, Lipniacki T, Levchenko A, Abdi A. Biology (Basel). 2023 Nov 23; 2023 Nov 23. PMID: 38132287.
- Identification of Key Influencers for Secondary Distribution of HIV Self-Testing Kits Among Chinese Men Who Have Sex With Men: Development of an Ensemble Machine Learning Approach.Jing F, Ye Y, Zhou Y, Ni Y, Yan X, Lu Y, Ong J, Tucker JD, Wu D, Xiong Y, Xu C, He X, Huang S, Li X, Jiang H, Wang C, Dai W, Huang L, Mei W, Cheng W, Zhang Q, Tang W. J Med Internet Res. 2023 Nov 23; 2023 Nov 23. PMID: 37995110.
- Focal adhesion-derived liquid-liquid phase separations regulate mRNA translation.Kumar A, Schwartz MA. bioRxiv. 2023 Nov 22; 2023 Nov 22. PMID: 38045367.
- HOXC6 drives a therapeutically targetable pancreatic cancer growth and metastasis pathway by regulating MSK1 and PPP2R2B.Malvi P, Chava S, Cai G, Hu K, Zhu LJ, Edwards YJK, Green MR, Gupta R, Wajapeyee N. Cell Rep Med. 2023 Nov 21; 2023 Nov 10. PMID: 37951219.
- Mutation of key signaling regulators of cerebrovascular development in vein of Galen malformations.Zhao S, Mekbib KY, van der Ent MA, Allington G, Prendergast A, Chau JE, Smith H, Shohfi J, Ocken J, Duran D, Furey CG, Hao LT, Duy PQ, Reeves BC, Zhang J, Nelson-Williams C, Chen D, Li B, Nottoli T, Bai S, Rolle M, Zeng X, Dong W, Fu PY, Wang YC, Mane S, Piwowarczyk P, Fehnel KP, See AP, Iskandar BJ, Aagaard-Kienitz B, Moyer QJ, Dennis E, Kiziltug E, Kundishora AJ, DeSpenza T Jr, Greenberg ABW, Kidanemariam SM, Hale AT, Johnston JM, Jackson EM, Storm PB, Lang SS, Butler WE, Carter BS, Chapman P, Stapleton CJ, Patel AB, Rodesch G, Smajda S, Berenstein A, Barak T, Erson-Omay EZ, Zhao H, Moreno-De-Luca A, Proctor MR, Smith ER, Orbach DB, Alper SL, Nicoli S, Boggon TJ, Lifton RP, Gunel M, King PD, Jin SC, Kahle KT. Nat Commun. 2023 Nov 17; 2023 Nov 17. PMID: 37978175.
- Loss of cis-PTase function in the liver promotes a highly penetrant form of fatty liver disease that rapidly transitions to hepatocellular carcinoma.Singh AK, Chaube B, Citrin KM, Fowler JW, Lee S, Catarino J, Knight J, Lowery S, Shree S, Boutagy N, Ruz-Maldonado I, Harry K, Shanabrough M, Ross TT, Malaker S, Suárez Y, Fernández-Hernando C, Grabinska K, Sessa WC. bioRxiv. 2023 Nov 15; 2023 Nov 15. PMID: 38014178.
- A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better.Djureinovic D, Weiss SA, Krykbaeva I, Qu R, Vathiotis I, Moutafi M, Zhang L, Perdigoto AL, Wei W, Anderson G, Damsky W, Hurwitz M, Johnson B, Schoenfeld D, Mahajan A, Hsu F, Miller-Jensen K, Kluger Y, Sznol M, Kaech SM, Bosenberg M, Jilaveanu LB, Kluger HM. Mol Cancer. 2023 Nov 14; 2023 Nov 14. PMID: 37964379.
- Calponin 2 regulates ketogenesis to mitigate acute kidney injury.Gui Y, Palanza Z, Gupta P, Li H, Pan Y, Wang Y, Hargis G, Kreutzer DL, Wang Y, Bastacky SI, Liu Y, Liu S, Zhou D. JCI Insight. 2023 Nov 8; 2023 Nov 8. PMID: 37751293.
- Abl2 repairs microtubules and phase separates with tubulin to promote microtubule nucleation.Duan D, Lyu W, Chai P, Ma S, Wu K, Wu C, Xiong Y, Sestan N, Zhang K, Koleske AJ. Curr Biol. 2023 Nov 6; 2023 Oct 18. PMID: 37858340.
- Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis Throughout the Day.Malik DM, Rhoades SD, Zhang SL, Sengupta A, Barber A, Haynes P, Arnadottir ES, Pack A, Kibbey RG, Sehgal A, Weljie AM. bioRxiv. 2023 Nov 2; 2023 Nov 2. PMID: 37961230.
- Clinical Trials and Climate Change: Doing Our Part While Pursuing Progress.Rahman S, Ryan S, Kim J, Kenney P, Ghali F. Eur Urol Focus. 2023 Nov; 2023 Dec 1. PMID: 38042649.
- Causal identification of single-cell experimental perturbation effects with CINEMA-OT.Dong M, Wang B, Wei J, de O Fonseca AH, Perry CJ, Frey A, Ouerghi F, Foxman EF, Ishizuka JJ, Dhodapkar RM, van Dijk D. Nat Methods. 2023 Nov; 2023 Nov 2. PMID: 37919419.
- Molecular Mechanism of Fasting-Mimicking Diet in Inhibiting Colorectal Cancer Progression: Implications for Immune Therapy and Metabolic Regulation.Bush CO, Perry RJ. Cancer Res. 2023 Nov 1. PMID: 37908187.
- SPAK-dependent cotransporter activity mediates capillary adhesion and pressure during glioblastoma migration in confined spaces.Lee SH, Yousafzai MS, Mohler K, Yadav V, Amiri S, Szuszkiewicz J, Levchenko A, Rinehart J, Murrell M. Mol Biol Cell. 2023 Nov 1; 2023 Sep 6. PMID: 37672340.