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Developmental Therapeutics

Ronald R Breaker

Henry Ford II Professor of Molecular, Cellular, and Developmental Biology; Investigator, Howard Hughes Medical Institute

Departments & Organizations

Molecular, Cellular, and Developmental Biology

NHLBI Proteomics

Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology: RNA Catalysis and Ribonucleoprotein Machines

Developmental Therapeutics

Center for RNA Science and Medicine, Yale

RNA Biology

Diabetes Endocrinology Research Center

Developmental Therapeutics


Research Interests

non-coding RNA; riboswitches; ribozymes; catalytic DNA; RNA's role in evolution more...


Selected Publications

  • J. L. Baker, N. Sudarsan, Z. Weinberg, A. Roth, R. R. Breaker (2012) Widespread Genetic Switches and Toxicity Resistance Proteins for Fluoride. Science 335:233-235.
  • E. R. Lee, J. L. Baker, Z. Weinberg, N. Sudarsan, R. R. Breaker (2010) An Allosteric Self-splicing Ribozyme Triggered by a Bacterial Second Messenger. Science 329:845-848.
  • Z. Weinberg, J. Perreault, M. M. Meyer, R. R. Breaker (2009) Exceptional Structured Noncoding RNAs Revealed by Bacterial Metagenome Analysis. Nature 462:656-659.

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