Steven H Kleinstein PhD

Associate Professor of Pathology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Immunology

Medical Informatics, Yale Center for

Cancer Immunology

Lymphocyte Development


Pathology: Informatics Program | Kleinstein Lab

Research Interests

Computational immunology; Systems biology; Disease/tissue/pathway/process modeling and simulation; Statistical and model-based analysis of experimental and clinical data  more...


  • Ph.D., Princeton University, 2002

Selected Publications

  • Yaari G, Uduman M and Kleinstein SH. Quantifying selection in high-throughput Immunoglobulin sequencing datasets. Nucleic Acids Research. 2012. doi:10.1093/nar/gks457. PMID: 22641856
  • Kerfoot SM, Yaari G, Patel J, Johnson K, Gonzalez D, Kleinstein SH, and Haberman AM. Inter-follicular germinal center B cell and T follicular helper cell development precedes follicular Tfh maintenance. Immunity. 2011. Jun 24;34(6):947-60. PMID: 21636295.
  • Christopher R. Bolen, Mohamed Uduman and Steven H. Kleinstein. Cell Subset Prediction for Improving Blood Genomic Studies. BMC Bioinformatics. 2011. Jun 24;12(1):258. PMID: 21702940.



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