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Xiaoyong Yang PhD

Associate Professor of Comparative Medicine and of Cellular and Molecular Physiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Molecular Medicine, Pharmacology, and Physiology

Cancer Center, Yale: Signal Transduction

Comparative Medicine: Integrative Cell Signaling & Neurobiology of Metabolism (ICSNM)

Cellular & Molecular Physiology: Graduate Program in Cellular and Molecular Physiology


Research Interests

Nutrient Sensing; Cell Signaling; Circadian Rhythms; Post-translational Modifications; Metabolic Physiology; Diabetes; Cancer; Aging; Systems Biology   more...


Education

  • M.S., Peking University, 1996
  • Ph.D., University of Alabama at Birmingham, 2001

Selected Publications

  • Li M.D., H.B. Ruan, M.E. Hughes, J.S. Lee, J.P. Singh, S.P. Jones, M.N. Nitabach, X. Yang. O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. Cell Metab. 2013, 17:303–10.
  • Ruan H.B., X. Han, M.D. Li, J.P. Singh, K. Qian, S. Azarhoush, L. Zhao, A.M. Bennett, V.T. Samuel, J. Wu, J.R. Yates III, X. Yang. O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1alpha stability. Cell Metab. 2012, 16:226–37.
  • Yang X. A wheel of time: the circadian clock, nuclear receptors, and physiology. Genes & Dev. 2010, 24:741-7.

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