Wu Liu PhD, DABR
Assistant Professor of Therapeutic Radiology
Research Interests
Image guided radiotherapy; Tumor motion monitoring and management; Dose reconstruction; Medical image analysis; Ultrasound parametric imaging
Current Projects
tumor motion monitoring and management
Research Summary
Clinical-oriented research on image guided radiotherapy: tumor motion monitoring and management. Dose reconstruction. Medical image analysis.
Applying artificial intelligence techniques to IGRT for margin reduction and adaptive imaging and planning.
Cancer diagnosis & treatment evaluation using advanced ultrasound parametric imaging.
Extensive Research Description
IGRT
Selected Publications
- Xie Y, Xing L, Gu J, Liu W. Tissue feature-based intra-fractional motion tracking for stereoscopic x-ray image guided radiotherapy. Physics in medicine and biology. 2013;58(11):3615-30. PubMed PMID: 23648334.
- Lin WY, Lin SF, Yang SC, Liou SC, Nath R, Liu W. Real-time automatic fiducial marker tracking in low contrast cine-MV images. Medical physics. 2013;40(1):011715:1-7. PubMed PMID: 23298085.
- Yan H, Li H, Liu Z, Nath R, Liu W. Hybrid MV-kV 3D respiratory motion tracking during radiation therapy with low imaging dose. Physics in medicine and biology. 2012;57(24):8455-69. PubMed PMID: 23202376.
- Qian J, Xing L, Liu W, Luxton G. Dose verification for respiratory-gated volumetric modulated arc therapy. Physics in medicine and biology. 2011;56(15):4827-38. PubMed PMID: 21753232; PubMed Central PMCID: PMC3360016.
- W. Liu, G. Luxton, and L. Xing, "A Failure Detection Strategy for Intrafraction Prostate Motion Monitoring with On-board Imagers for Fixed-Gantry IMRT," International Journal of Radiation Oncology Biology Physics, 78(3): 904-911, 2010.
- W. Liu, J. Qian, S. Hancock, L. Xing, and G. Luxton, "Clinical development of a failure detection-based online repositioning strategy for prostate IMRT – experiments, simulation, and dosimetry study" Medical Physics, 37(10): 5287-5297, 2010.
- W. Liu, R. Wiersma, and L. Xing, "Optimized Hybrid MV-kV Imaging Protocol for Volumetric Prostate Arc Therapy," International Journal of Radiation Oncology Biology Physics, 78(2): 595-604, 2010.
- J. Qian, L. Lee, W. Liu, K. Chu, E. Mok, G. Luxton, Q. Le, and L. Xing, “Dose Reconstruction for volumetric modulated arc therapy using cone-beam CT and dynamic log-files”, Physics in Medicine & Biology, 55: 3597-3610, 2010
- W. Liu and J. A. Zagzebski, "Tradeoffs in Data Acquisition and Processing Parameters for Backscatter and Scatterer Size Estimations," IEEE Trans Ultrason Ferroelectr Freq Control, 57(2): 340-352, 2010.
- W. Liu, R.D. Wiersma, W. Mao, G. Luxton, and L. Xing, “Real-time 3D internal marker tracking during arc radiotherapy by use of combined MV-kV imaging”, Physics in Medicine & Biology, 53: 7197-7213, 2008
Selected Publications
- Xie Y, Xing L, Gu J, Liu W. Tissue feature-based intra-fractional motion tracking for stereoscopic x-ray image guided radiotherapy. Physics in medicine and biology. 2013;58(11):3615-30. PubMed PMID: 23648334.
- Lin WY, Lin SF, Yang SC, Liou SC, Nath R, Liu W. Real-time automatic fiducial marker tracking in low contrast cine-MV images. Medical physics. 2013;40(1):011715:1-7. PubMed PMID: 23298085.
- Yan H, Li H, Liu Z, Nath R, Liu W. Hybrid MV-kV 3D respiratory motion tracking during radiation therapy with low imaging dose. Physics in medicine and biology. 2012;57(24):8455-69. PubMed PMID: 23202376.
- Qian J, Xing L, Liu W, Luxton G. Dose verification for respiratory-gated volumetric modulated arc therapy. Physics in medicine and biology. 2011;56(15):4827-38. PubMed PMID: 21753232; PubMed Central PMCID: PMC3360016.
- W. Liu, G. Luxton, and L. Xing, "A Failure Detection Strategy for Intrafraction Prostate Motion Monitoring with On-board Imagers for Fixed-Gantry IMRT," International Journal of Radiation Oncology Biology Physics, 78(3): 904-911, 2010.
- W. Liu, J. Qian, S. Hancock, L. Xing, and G. Luxton, "Clinical development of a failure detection-based online repositioning strategy for prostate IMRT – experiments, simulation, and dosimetry study" Medical Physics, 37(10): 5287-5297, 2010.
- W. Liu, R. Wiersma, and L. Xing, "Optimized Hybrid MV-kV Imaging Protocol for Volumetric Prostate Arc Therapy," International Journal of Radiation Oncology Biology Physics, 78(2): 595-604, 2010.
- J. Qian, L. Lee, W. Liu, K. Chu, E. Mok, G. Luxton, Q. Le, and L. Xing, “Dose Reconstruction for volumetric modulated arc therapy using cone-beam CT and dynamic log-files”, Physics in Medicine & Biology, 55: 3597-3610, 2010
- W. Liu and J. A. Zagzebski, "Tradeoffs in Data Acquisition and Processing Parameters for Backscatter and Scatterer Size Estimations," IEEE Trans Ultrason Ferroelectr Freq Control, 57(2): 340-352, 2010.
- W. Liu, R.D. Wiersma, W. Mao, G. Luxton, and L. Xing, “Real-time 3D internal marker tracking during arc radiotherapy by use of combined MV-kV imaging”, Physics in Medicine & Biology, 53: 7197-7213, 2008
- W. Liu, J.A. Zagzebski, H.J. Hall, E.L. Madsen, T. Varghese, M.A. Kliewer, S. Panda, C. Lowery, and S. Barnes, “Acoustic backscatter and effective scatterer size estimates using a 2D CMUT transducer”, Physics in Medicine & Biology, 53: 4169-4183, 2008
- Liu W, Zagzebski JA, Varghese T, Gerig AL, Hall TJ. Spectral and scatterer-size correlation during angular compounding: simulations and experimental studies. Ultrasonic imaging. 2006;28(4):230-44. PubMed PMID: 17521044.
- Liu W, Zagzebski JA, Varghese T, Dyer CR, Techavipoo U, Hall TJ. Segmentation of elastographic images using a coarse-to-fine active contour model. Ultrasound in medicine & biology. 2006;32(3):397-408. PubMed Central PMCID: PMC1764611.
- Bharat S, Techavipoo U, Kiss MZ, Liu W, Varghese T. Monitoring stiffness changes in lesions after radiofrequency ablation at different temperatures and durations of ablation. Ultrasound in medicine & biology. 2005;31(3):415-22. PubMed PMID: 15749565.
- Techavipoo U, Varghese T, Zagzebski JA, Chen Q, Liu W. Semiautomated thermal lesion segmentation for three-dimensional elastographic imaging. Ultrasound in medicine & biology. 2004;30(5):655-64. PubMed PMID: 15183232.
- Liu W, Techavipoo U, Varghese T, Zagzebski JA, Chen Q, Lee FT, Jr. Elastographic versus x-ray CT imaging of radio frequency ablation coagulations: an in vitro study. Medical physics. 2004;31(6):1322-32. PubMed PMID: 15259635.
- Varghese T, Techavipoo U, Liu W, Zagzebski JA, Chen Q, Frank G, et al. Elastographic measurement of the area and volume of thermal lesions resulting from radiofrequency ablation: pathologic correlation. AJR American journal of roentgenology. 2003;181(3):701-7. PubMed PMID: 12933463.
