Program Members
Co-Leaders
Karen Anderson
Professor of Pharmacology and of Molecular Biophysics and Biochemistry
Co-Director Therapeutics/Chemotherapy Program
- Office:(203) 785-4526
- Lab:(203) 737-1527
Roy Herbst
Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology
Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven
Associate Director for Translational Research, Yale Cancer Center
Clinical Research Program Leader, Thoracic Oncology Program, Yale Cancer Center
Clinical Interests:Lung cancer; Thoracic Oncology; Personalized Cancer Medicine; Clinical Trials for Lung cancer; Tumor profiling; Tumor biomakers
- Office:(203) 785-6879
- Appt:(203) 200-5864
Members
Maysa Abu-Khalaf
Associate Professor of Medicine (Medical Oncology) and of Obstetrics, Gynecology, and Reproductive Sciences
Research Interests:Clinical trials evaluating novel agents for the treatment of breast, ovarian and endometrial cancers; PI3K-mTOR inhibitors; HER-2 targeted therapies; angiogenesis
- Office:(203) 737-8309
- Appt:(203) 200-2328
Joachim Baehring
Associate Professor of Neurology, of Medicine (Medical Oncology) and of Neurosurgery
Clinical Program Leader, Brain Tumor Program, Smilow Cancer Hospital
Research Interests:Molecular markers of cancer; Nervous system lymphoma
- Appt:(203) 785-7284
Ronald Breaker
Henry Ford II Professor of Molecular, Cellular, and Developmental Biology
Investigator, Howard Hughes Medical Institute
Research Interests:non-coding RNA; riboswitches; ribozymes; catalytic DNA; RNA's role in evolution
- Office:(203) 432-9389
- Lab:(203) 432-6554
Charles Cha
Associate Professor of Surgery (Oncology and Gastrointestinal)
Research Interests:Development of robotic and laparoscopic approaches for benign and malignant conditions of the liver, pancreas and stomach; Effects of angiogenesis on gastrointestinal malignancy; Gene silencing techniques to knockdown proliferation of hepatocellular carcinoma in vitro and in vivo; Diagnostic and therapeutic utility of angiogenic inhibitors for treatment of solid tumors; Clinical outcomes in surgery for sarcoma, hepatobiliary, gastric and esophageal malignancy
- Appt:(203) 785-2380
Herta Chao
Associate Professor of Medicine (Medical Oncology)
Research Interests:Prostate cancer; androgen deprivation therapy; cognitive function; lung cancer; phospho-inositol-3 kinase pathway as a drug target
Yung-Chi Cheng
Henry Bronson Professor of Pharmacology
Chairman, Consortium for the Globalization of Chinese Medicine (CGCM)
Research Interests:Cancer; Viral chemotherapy; Chinese herbs; Chinese medicine
- Office:(203) 785-7118
- Lab:(203) 785-7119
Jennifer Choi
Assistant Professor of Dermatology
Director, Yale Oncodermatology Clinic
Research Interests:Cutaneous side effects of chemotherapy and radiation; Melanoma treatment
- Office:(203) 785-4092
- Appt:(203) 789-1249
Gina Chung
Assistant Professor of Medicine (Medical Oncology)
- Office:(203) 785-2876
- Appt:(203) 200-2328
Craig Crews
Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry and of Pharmacology
Executive Director, Yale Molecular Discovery Center
Research Interests:Limb regeneration; wound epidermis; blastema; natural product mode of action studies; angiogenesis; Wnt signaling; protein turnover; protein kinase regulation
- Office:(203) 432-9364
- Lab:(203) 432-6553
Hari Deshpande
Assistant Professor of Medicine (Medical Oncology) and of Surgery (Otolaryngology) and Assistant Clinical Professor of Nursing
Research Interests:Clinical trials in head and neck cancer; sarcoma; Genitourinary (GU) cancer; thyroid and endocrine cancers
- Office:(203) 737-1600
- Appt:(203) 200-4822
Vincent DeVita, Jr
Amy and Joseph Perella Professor of Medicine (Medical Oncology) and Professor of Epidemiology (Chronic Diseases) and of Medicine (Medical Oncology)
Research Interests:Drug Resistance; Hodgkin's Disease; Lymphomas; Molecular Technology; Primary Chemotherapy
- Office:(203) 737-1010
Joseph Eder
Research Interests:Phase I clinical trials; Cancer pharmacology; Angiogenesis
- Appt:(203) 200-4422
Barbara Ehrlich
Professor of Pharmacology and of Cellular and Molecular Physiology
Research Interests:Intracellular calcium regulation
- Office:(203) 737-1158
- Lab:(203) 737-1158
Jonathan Ellman
Professor of Chemistry
Pharmacology
Research Interests:proteases, phosphatases, inhibitors, C-H functionalization, asymmetric amine synthesis
Donald Engelman
Eugene Higgins Professor of Molecular Biophysics and Biochemistry
Research Interests:Helix Interactions; Lipid Bilayers; Membranes; Physical Biochemistry; Protein Folding; Proteins
Scott Gettinger
Associate Professor of Medicine (Medical Oncology)
Research Interests:Clinical trial design; novel therapeutics; radiosensitizers; prognostic biomarkers
- Appt:(203) 200-5864
Ya Ha
Associate Professor of Pharmacology
Research Interests:Membrane protein; X-ray crystallography; Enzyme mechanism
- Office:(203) 785-7530
- Lab:(203) 785-7360
Howard Hochster
Professor of Medicine (Medical Oncology)
Associate Director for Clinical Sciences, Yale Cancer Center
Clinical Program Leader, Gastrointestinal Cancers Program, Smilow Cancer Hospital
Clinical Research Program Leader, Gastrointestinal Cancers Program, Yale Cancer Center
Research Interests:clinical research; pharmacology; anti cancer drug development; early clinical trials in cancer
- Appt:(203) 200-4422
Michael Hodsdon
Associate Professor of Laboratory Medicine and of Pharmacology
Assoc. Director, Clinical Chemistry Laboratory
Research Interests:Biochemistry; Biophysics; Breast Cancer; Clinical Chemistry; Drug Metabolism; Health and Medicine; Laboratory Practice or Procedure; Nuclear Magnetic Resonance; Pathobiology; Pharmacology; Spectroscopy; Structural Biology; Toxicology
- Office:(203) 688-2, 2
- Appt:(203) 688-2445
Zhiwei Hu
Research Scientist
Research Interests:Cancer Immunotherapy; Photodynamic Therapy; Tumor Angiogenesis; Cancer Stem Cell; Tumor Immunology; Natural Killer Cells
- Lab:(203) 737-4669
Sven-Eric Jordt
Associate Professor of Pharmacology
Research Interests:Sense of touch and pain in humans and animals; Chemosensory processes in sensory neurons and their role in chemical environmental exposures; Neural sensitization in asthma; Hypersensitivity disorders
- Office:(203) 785-2159
- Lab:(203) 737-1560
William Jorgensen
Sterling Professor of Chemistry
Director, Division of Physical Sciences & Engineering
Michael Kinch
Associate Research Scientist in and Lecturer in Molecular, Cellular, and Developmental Biology
Harriet Kluger
Associate Professor of Medicine (Medical Oncology)
Associate Director, Hematology/Oncology Fellowship Program
Research Interests:Prognostic and predictive markers in melanoma and renal cell carcinoma; development of new drugs for melanoma and renal cell carcinoma
- Appt:(203) 200-6622
Jaseok Koo
Associate Professor of Medicine (Medical Oncology)
Research Interests:Cancer prevention and therapy; Lung carcinogenesis; Epithelial cell biology; Personalized medicine; Molecular targets; Drug development; Transcription Factor CREB; Inflammation; Cytokines and chemokines and receptors; Biomarkers for early detection and therapy
Jill Lacy
Associate Professor of Medicine (Medical Oncology)
Research Interests:Clinical research in gastrointestinal malignancies, including gastroesphageal, pancreatic, and colorectal cancers, and brain tumors; Epstein-Barr virus-associated malignancies
- Appt:(203) 200-4422
Elias Lolis
Professor of Pharmacology
Director of Graduate Studies
Research Interests:Cancer; Inflammation; Infectious disease; macromolecular X-ray crystallography; Signaling pathways; Drug design; High throughput screening (HTPS)
- Office:(203) 785-6233
- Lab:(203) 737-1526
Thomas Lynch
Richard Sackler and Jonathan Sackler Professor of Medicine (Medical Oncology)
Director, Cancer Center
Research Interests:Lung cancer; EGFR; Targeted therapy; Personalized medicine
- Appt:(203) 200-5864
Gil Mor
Professor of Obstetrics, Gynecology, and Reproductive Sciences
Division Director, Reporductive Sciences
Director Reproductive Immunology Unit and Discovery to Cure Program
Editor in Chief, AJRI
Research Interests:Immunology of Gynecologic tumors; Immunology of Implantation; Ovarian Cancer Stem Cells
- Office:(203) 785-6294
- Lab:(203) 737-1405
Daniel Morgensztern
Assistant Professor of Medicine (Medical Oncology)
Research Interests:Lung cancer; targeted therapy; molecular diagnosis; prognosis; supportive care; epidemiology; head and neck cancer
- Appt:(203) 200-5864
Peter Peduzzi
Professor of Public Health (Biostatistics)
Director, Yale Center for Analytical Sciences (YCAS)
Research Interests:Clinical trials; comparative effectiveness research; general statistical methods; variable selection
Joseph Piepmeier
Nixdorff-German Professor of Neurosurgery
Vice Chair of Clinical Affairs, Neurosurgery
Section Chief, Neuro-Oncology
Director, Surgical Neuro-Oncology
Clinical Research Program Leader, Brain Tumor Program, Yale Cancer Center
Research Interests:neuro-oncology; acoustic neuroma; general neurosurgery; brain and spinal cord cancer; brachytherapy; stereotactic needle biopsy
- Appt:(203) 785-2791
Nikolai Podoltsev
Assistant Professor of Medicine (Hematology)
Associate Director of the Hematology/Oncology Fellowship Program
- Appt:(203) 200-4363
Lynne Regan
Professor of Molecular Biophysics and Biochemistry and of Chemistry
Research Interests:Mental retardation; protein-protein interactions; Fragile X Mental Retardation Protein (FMRP); protein-based nanomaterials
John Roberts
Director, Adult Sickle Cell Program at Yale-New Haven Hospital
Research Interests:Clinical trials; clinical trials design.
Michal Rose
Associate Professor of Medicine (Medical Oncology)
Director, VA Comprehensive Cancer Center
Chair, Data and Safety Monitoring Committee, Yale Cancer Center
- Office:(203) 937-3421
Thomas Rutherford
Professor of Obstetrics, Gynecology, and Reproductive Sciences
Section Chief, Gynecologic Oncology
Research Interests:Minimally invasive surgical techniques; Ovarian stem cell research; Micro-RNA; Novel biologic agents for treatment; Early detection of ovarian cancer
- Office:(203) 785-6301
- Appt:(203) 200-4176
W. Mark Saltzman
Goizueta Foundation Professor of Biomedical Engineering and Professor of Cellular and Molecular Physiology and of Chemical Engineering
Department Chair, Biomedical Engineering
Research Interests:Bio-compatible polymers, drug delivery systems
- Office:(203) 432-4262
Alan Sartorelli
Alfred Gilman Professor of Pharmacology
Research Interests:Cancer research; Drug development; Drug resistance
- Office:(203) 785-4533
- Lab:(203) 785-4534
Clarence Sasaki
Charles W. Ohse Professor of Surgery (Otolaryngology)
Research Interests:Laryngeal physiology, head and neck cancer
- Appt:(203) 785-2592
William Sessa
Alfred Gilman Professor of Pharmacology and Professor of Medicine (Cardiology)
Vice Chairman, Pharmacology
Director, Vascular Biology & Therapeutics Program
Research Interests:Vascular endothelium and inflammation; MiRNAs; Vascular development and angiogenesis; Lipid domains and signaling; Atherosclerosis
- Office:(203) 737-2291
David Spiegel
Associate Professor of Chemistry
Research Interests:Design of novel molecules that enhance the recognition of various pathogens, including viruses, by the human immune system
- Office:(203) 432-8697
