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Current Funding Opportunities

NCCN Request for Proposals (RFP): Phase I/II Clinical Trials and Pre-Clinical Trials of Enzalutamide for Endometrial Cancer

National Comprehensive Cancer Network® (NCCN®) is pleased to announce that it has received a research grant from Astellas Pharma, Inc. and Medivation, Inc. to support NCCN investigator initiated clinical and pre-clinical studies of enzalutamide in the treatment of endometrial cancer. 

Investigators are asked to submit short proposals detailing proposed studies.  The overall aim of this RFP is to develop innovative studies of enzalutamide in endometrial cancer.  Collaborative studies between NCCN Member Institutions are encouraged.


Proposals are due by 5 pm EDT on Monday, April 27, 2015.  For additional information, please contact Doreen Walker, Administrative Assistant, Oncology Research Program, at (215) 690-0565 or via email at Walker@nccn.org.
The NCCN views this major award by Astellas Pharma, Inc. and Medivation, Inc. as clear recognition of the advantages offered to industry through the NCCN Oncology Research Program.  We hope you and your colleagues will be interested in this opportunity.  

2015 Yale-CORE Career Development Program in Patient-Centered Outcomes Research

The Yale-CORE Career Development Program in Patient-Centered Outcomes Research (Y-CORE PCOR) is an AHRQ-funded K12 program within the Yale-New Haven Hospital Center for Outcomes Research and Evaluation that is designed to train junior faculty and postdoctoral fellows in patient-centered outcomes research. Y-CORE PCOR will provide training and career development support for 2 scholars who have a clinical or research doctoral degree and are committed to a career in patient-centered outcomes research (PCOR) and comparative effectiveness research (CER).

Elements of the program include: Mentor Advisory Panels (MAPs) that will advise and guide each scholar, including a patient consultant; option to complete the MHS along with targeted advanced coursework for PCOR; training and experience in research prioritization, data generation and evidence synthesis; mentored participation in a community review board to develop skills in patient centeredness; 75% salary support/protected time in addition to funds for educational and research pursuits.

Requirements

  • Applicants must have earned a clinical or research doctorate, including PhD, ScD, DrPH, MD, DO, DC, ND, DDS, DMD, DNS or equivalent doctoral degree at the time of appointment and demonstrate commitment to conducting CER, applied to PCOR.
  • At the time of the award, applicant must have a “full-time” appointment at Yale University or provide a letter from the applicant’s home department committing to a full-time appointment if recipient of a Y-CORE PCOR award.
  • Applicants must be able to commit a minimum of nine person-months (75% of full-time professional effort) conducting research career development activities associated with this award for a two or three year period. The remaining three months (25% effort) can be divided among other research, clinical, and teaching activities only if these activities are consistent with the goals of the award, i.e., the candidate’s development into an independent investigator.
  • Applicants may request as much as $90,000 for salary support plus associated fringe and as much as $20,000 for research support per year.
  • Applicants must be US citizens or non-citizen nationals, or individuals lawfully admitted for permanent residence. Additional details on citizenship requirements are available in the HHS Grants Policy Statement at http://dhhs.gov/asfr/ogapa/grantinformation/hhsgps107.pdf.

Application deadline: Extended to May 29, 2015 by 5:00 pm

Anticipated start date: July 1, 2015

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Simons Foundation Faculty Scholars Competition

The Simons Foundation, Howard Hughes Medical Institute (HHMI) and the Bill & Melinda Gates Foundation are pleased to announce the Faculty Scholars Competition, a national competition for grants to outstanding early-career scientists.
The three philanthropies will award a total of $148 million over the program's first five years, awarding up to 70 grants every two and a half to three years. The awards are intended for basic researchers and physician scientists who have already demonstrated significant research accomplishments and show potential to make unique and important contributions to their fields.
The Faculty Scholars Competition marks the first time that HHMI, the Bill & Melinda Gates Foundation and the Simons Foundation have formally undertaken an initiative together.

Application Deadline: July 28, 2015

NCCN Request for Proposals (RFP): Phase I/II Clinical Trials and Pre-Clinical Trials of Enzalutamide for Endometrial Cancer

The National Comprehensive Cancer Network® (NCCN®) received a research grant from Astellas Pharma, Inc. and Medivation, Inc. (hereafter, “Grantor”) to support NCCN Member Institution faculty for the design and performance of clinical and pre-clinical studies of enzalutamide in the treatment of selected solid tumors. NCCN will serve as the funding organization for these grants that are available only to NCCN investigators.

The original RFP, issued on June 30, 2014, called for studies in all solid tumors. It was well received and three innovative clinical/correlative studies in various tumor types were selected for funding. Funds of $450,000 are still available to support novel preclinical and clinical studies of enzalutamide in patients with endometrial cancer. Pre-clinical laboratory and correlative/translational studies investigating the clinical relevance of AR expression to disease biology and progression or mechanisms of resistance to enzalutamide will also be considered. Clinical trials and preclinical studies involving rational enzalutamide combination approaches will be considered if supported by strong mechanistic rationale.

Consideration will be given to the following highlighted areas of interest:
• Phase II studies in patients with endometrial cancer;
• Rationally justified (e.g. supported by preclinical data), phase I/II studies of novel combinations with other agents;
• Biomarker or pharmacodynamic studies aimed at determining the clinical relevance of AR expression and response to enzalutamide;
• Novel studies that incorporate evaluation of tissue effects of AR targeting (e.g. tumor response, phenotypic changes, etc.);
• Preclinical and translational studies of novel combinations that could provide data for a future clinical study.
Other:
• Mechanistic studies aimed at understanding AR-driven oncogenesis or AR-dependent progression in endometrial cancer;
• Preclinical studies to evaluate/understand immune mediated response and immune modulation by enzalutamide in endometrial cancer;
• Health related quality of life outcome measures are encouraged as part of clinical studies.

All proposals must be submitted electronically using the directions below and are due by 5:00 PM (EDT) on April 27, 2015. No exceptions will be granted.


YCC/SCH Grants for Small Projects to Improve Patient Care

Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven are pleased to announce a new program to fund small projects to improve patient care at Smilow Cancer Hospital. Monies for this program have come through our “Closer to Free” fund. Any employee at Smilow Cancer Hospital who develops a small project may apply by submitting an application for review. Projects can range from a patient education program to stress management for staff. In order to be eligible, the employee must be sponsored by a current Cancer Center Member. A listing of active cancer center members is on the web site.

Grant Details

Amount: $2,500 to $5,000 each

Eligibility: Employees of Smilow Cancer Hospital at Yale-New Haven

Sponsorship: Member of Yale Cancer Center

Application: Limited to 3 pages, typed, double spaced; plus budget with justification (3 copies)

- Application sheet: Project Due Date

- Project Description

- Budget

- Budget Justification

Submit to Renee Gaudette: renee.gaudette@yale.edu

For questions, contact Dr. Ruth McCorkle by email: ruth.mccorkle@yale.edu

Application

Breast Cancer Alliance (BCA) Announces three Grant Opportunities for 2016

The mission of the BCA is to improve survival rates and quality of life for those impacted by breast cancer through prevention, early detection, treatment and cure. To promote these goals, we invest in innovative research, breast surgery fellowships, regional education, dignified support and screening for the underserved.

Exceptional Project Grant:

The Breast Cancer Alliance invites clinical doctors and research scientists at any stage of their careers whose primary focus is breast cancer to apply for an Exceptional Project Grant. The award recognizes creative, unique, and innovative research and is open to applicants at institutions within a 200-mile radius of Greenwich, CT. This is a one-year grant for a total of $100,000. Prior to submission of a formal grant proposal, the BCA requires a one-page Letter of Intent (LOI) and a separate CV. For 2015 grants, those letters will be due on April 2, 2015. The LOI must include the applicant’s name, job title, and institution at the top of the page, and the applicant’s contact information. The document should state the project title and hypothesis, outline the research aim(s) and methods, and include a brief discussion of the project’s potential impact. The CV can be in the NIH biosketch format and should be no more than four pages long. Applicants will be informed by the first week of May 2015 whether they have been invited to proceed with a formal application. Researchers should coordinate with their institutions, as the BCA will accept a maximum of three LOIs per institution.  (Full proposals, if invited, will be due on or before July 24, 2015.)

Please note that the Exceptional Project Grant due date for LOIs selected by the Yale Scholar Award Committee is April 2.

Young Investigator Grants : Note: No limit on the number of submissions per institution.

To encourage a commitment to breast cancer research, the Breast Cancer Alliance invites clinical doctors and research scientists whose primary focus is breast cancer and who are in the early stages of their careers to apply for funding for the Young Investigator Grant. This grant is open to applicants at institutions within a 200-mile radius of Greenwich, CT. This is a two-year grant for a total of $125,000, with half the grant award being paid out each year.

Applicants for 2016 grants much (i) have held a faculty position for no more than four years following the completion of their training, as of February 1, 2015; (ii) have not been a principal investigator on an NIH R01 or equivalent national/international non-mentored award; and (iii) dedicate at least 50% of their work effort to research. This grant is intended to help advance the careers of young researchers who do not yet have their own major grant support. Grant applications are due on or before July 24, 2015. An independent External Review Committee reviews and evaluates the applications. Based on their results and subsequent review by the Grants Committee, recommendations will be made to the BCA Board for final approval. Applicants will be notified in mid-December of the decision regarding their proposals. To download an application, click here: 2016-YIG-application For questions about any research grants, please e-mail: researchgrants@breastcanceralliance.org

Education and Outreach Grants:

The Breast Cancer Alliance offers grants to support programs directly related to outreach and case managerial breast cancer services, including education, counseling, and mammograms for the uninsured/underserved. The programs must be located in Connecticut and/or Westchester County, New York. This is a one-year grant.

For 2016 grants, final applications are due on or before July 31, 2015. The Grants Committee of the Breast Cancer Alliance reviews and evaluates each grant proposal. The results of the Grants Committee’s evaluations and subsequent recommendations are presented to the BCA Board for approval. Applicants are notified in mid-December of the decision regarding their proposals. To download the final report form for 2014 grants, click here for the 2014 Final Report

For questions about any education and outreach grants please email: edout@breastcanceralliance.org

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Alex's Lemonade Stand Foundation "A" Awards

Designed for early career scientists with an original project who can demonstrate outstanding mentorship and have a strong future commitment to pediatric cancer investigation. The grant is open to MD, MD/PhD and PhD investigators. Maximum of $450,000 awarded over three years.

Application Deadline: May 22, 2015

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2nd Annual Claire Puklin Award for Clinical Excellence in Urologic Nursing
The Smilow Cancer Hospital at Yale New Haven and the Yale School of Medicine Department of Urology announce the first annual award named in honor of our colleague, Claire Puklin, RN.  This award is being established to recognize exemplary clinical practice by a staff nurse involved in the care of Urology patients at the Smilow Cancer Hospital or YNHH Urology practices.  Criteria upon which candidate selection will be based:
  • Embraces the Smilow Cancer Hospital/YNHH vision and mission to deliver outstanding patient centered care in the field of Urology. 
  • Recognized as a clinical expert and an advocate for patients and families, demonstrates a commitment to providing compassionate care and role models service excellence behaviors.
  • Demonstrates advanced assessment skills and employs critical thinking to meet identified patient/family needs on a consistent basis.  
  • Demonstrates the ability to communicate and collaborate effectively with all members of the multidisciplinary team.  
  • Role models excellence in clinical practice and motivates colleagues to engage in best practices in the delivery of patient centered care. 
  • Proactively shares knowledge, clinical expertise and special skills with colleagues and the team.
  • Active involvement in unit or institutional committees to advance patient centered care.
Applications are due by Friday, May 1st and will be reviewed by the Smilow Recognition Task Force.  The recipient will be selected by the Chair of Urology and the Executive Director of Smilow Patient Care services.  The award will be presented at the Oncology Nursing Month Breakfast.   The recipient will receive a $1000 travel award grant to be used to attend the Society for Urological Nursing/Associates annual conference.


4th Annual Oncology/ Research PCA Educational Grant
The Smilow Cancer Hospital at Yale New Haven announces its second annual Oncology/ Research PCA Educational Grant.  This award was established to focus attention on the Smilow Cancer Hospital vision, mission and philosophy and to recognize exemplary contributions of a Patient Care Associate involved in the care of patients with cancer at the Smilow Cancer Hospital.  Following are criteria upon which candidate selection will be based:
  • Embraces the Smilow Cancer Hospital vision and mission to deliver patient centric, multidisciplinary patient/family care.
  • Recognized as an advocate for patients and families, demonstrates a commitment to providing compassionate care with respect for the concerns of patients and their families and role models service excellence behaviors.
  • Demonstrates the ability to communicate and collaborate effectively with all members of the cancer care team, patients and their families. 
  • Role models excellence and motivates colleagues to engage in best practices in the delivery of patient/family care. 
  • Proactively shares knowledge, and provides support with colleagues and the nursing staff.
  • Accepted or enrolled in an accredited School of Nursing
Please have submissions returned by Friday, May 1st to your PSM. Applications will be reviewed and final selection will be made by the Oncology Recognition Task Force.  Recipients will be notified in an official letter from the Smilow Cancer Hospital Clinical Program Director/Director of Nursing.  The recipient will receive a $500 grant to be used towards advancing their education towards a nursing degree.


6th Annual Oncology/ Research Nursing Award for Clinical Excellence
The Smilow Cancer Hospital at Yale New Haven announces its fifth annual Oncology/ Research Nursing Award for Clinical Excellence.  This award was established to focus attention on the Smilow Cancer Hospital vision, mission and philosophy and to recognize exemplary clinical practice contributions of a staff nurse involved in the care of patients with cancer at the Smilow Cancer Hospital.  Following are criteria upon which candidate selection will be based:
  • Embraces the Smilow Cancer Hospital vision and mission to deliver patient centric, multidisciplinary patient/family care.
  • Recognized as an advocate for patients and families, demonstrates a commitment to providing compassionate care with respect for the concerns of patients and their families and role models service excellence behaviors and exhibits safe, high quality care.
  • Demonstrates advanced assessment skills and employs critical thinking to meet identified patient/family needs on a consistent basis 
  • Demonstrates the ability to communicate and collaborate effectively with all members of the cancer care team, patients and their families. 
  • Role models practice excellence and motivates colleagues to engage in best practices in the delivery of patient/family care. 
  • Proactively shares knowledge, clinical expertise and special skills with colleagues and the team.
  • Serves actively on unit or institutional committees to advance patient/family care.

Please have submissions returned by Friday, May 1st to your PSM. Applications will be reviewed and final selection will be made by the Oncology Recognition Task Force.  Recipients will be notified in an official letter from the Smilow Cancer Hospital Executive Director/Director of Nursing.  The recipient will receive a $500 grant to be used for an approved continuing education program or programs and a personalized commemorative award.