Awards & Honors
Benjamin Toll, PhD has been awarded an R21 grant from the NIH to implement a smoking cessation clinical trial evaluating the differences between standard care intervention (counseling plus nicotine replacement) and standard care plus monetary rewards for smoking cessation in presurgical cancer patients. The primary aim of the proposed study is to develop an effect size for smoking cessation at the time of surgery (7-day point prevalence), with a secondary aim of creating an effect size for long-term abstinence at 3 months post-surgery. He and his research team will also examine exploratory outcomes of perioperative complications and rates of continuous abstinence. Dr. Roy Herbst is a co-investigator on the trial with Dr. Toll.
Linda Niccolai, PhD was awarded an administrative supplement grant to the Cancer Center core grant for one year of support to fund her project on "Increasing Human Papillomavirus Vaccination Coverage among Adolescents in Connecticut."
James Yu, MD received a PhRMA Foundation Research Starter Grant at the Turning The Tide Against Cancer Conference last week. The grant will support his research on "Quantifying the Benefit of Modern Cancer Therapy for Elderly Patients: A Population Level Measurement."
Congratulations to Dr. Vincent DeVita, the Amy and Joseph Perella Professor of Medical Oncology and former Director of Yale Cancer Center, who received the prestigious honor of having developed the treatment for Hodgkins Disease, MOPP, which was voted as the Top Advance in 50 Years of Modern Oncology by the American Society of Clinical Oncology (ASCO).
Melinda Irwin, PhD has received a two-year grant from the American Institute for Cancer Research. The AICR award will expand Dr. Irwin's LEAN study and enroll 200 overweight breast cancer survivors and complete a 6-month post-intervention assessment of maintenance of weight, as well as changes in physical activity, diet, and quality of life.
Qin Yan, PhD, Associate Professor of Pathology, and a member of the Yale Cancer Center Cancer Genetics and Genomics Program, was awarded a Department of Defense Breast Cancer Research Program Breakthrough Award to support his research project, "Targeting an Epigenetic Regulator to Suppress Breast Cancer Metastasis." This 3-year project ($700,000 direct cost and $1,165,498 in total cost) will be conducted in collaboration with Drs. Don Nguyen, David Stern, and Carmen Booth.
Narendra Wajapeyee, PhD, Assistant Professor of Pathology, and a member of the Yale Cancer Center Signal Transduction Program, received a Biomedical Research Grant from the American Lung Association for his studies on "Personalized therapy of p53-mutant lung cancers."
Don Nguyen, PhD, a member of the Yale Cancer Center Signal Transduction Program, was awarded a 2-year R21 grant from the NCI, entitled: "Epigenetic modulation of lung cancer metastasis by a novel long intergenic RNA." The project will be done in collaboration with Dr. David Rimm.
Melinda Irwin, PhD, Co-director of the Cancer Prevention and Control Program, has received a grant from the CT Breast Health Initiative to support dissemination of Lifestyle, Exercise, and Nutrition (LEAN) Study intervention by testing her team's LEAN book as an intervention without the addition of counseling.
Stephanie Halene, MD, received a grant from the Evans Foundation to support her research on Molecular mechanisms underlying deregulated hematopoiesis caused by mutations in the serine-rich splicingfactor 2 (SRSF2) in myelodysplasia (MDS). Her collaborators on the grant include Giovanni Stefani, Toma Tebaldi, Scott Hiebert, Yorgo Modis, Yuval Kluger, and Manoj Pillai.
Lieping Chen, MD, PhD, the United Technologies Corporation Professor of Cancer Research at Yale Cancer Center and Professor of Immunobiology, Dermatology, and Medicine at Yale School of Medicine, has been named a 2014 William B. Coley Award winner. The Coley award is the top prize given by the Cancer Research Institute at its annual symposium. Dr. Chen will give the 22nd annual William B. Coley lecture during the symposium in New York City this October.
The Department of Public Health has released the 2014 Biomedical Trust Fund Award Grants. Three Yale Cancer Center members have received grant funds:
Stephanie Halene, PhD: The goal of this project is to identify mechanisms of relapse in patients with acute myeloid leukemia (AML) and to model AML relapse in humanized immunodeficient mice with the ultimate goal to develop and test novel treatments.
Collaborators: Richard Flavell, Anthony Rongvaux, Nikolai Podoltsev, Steven Gore, Natalia Neparidze, Terri Parker, Caroline Cromwell, Alfred Lee, Steven Kleinstein, and Shrikant Mane.
Edward Kaftan, PhD: The goals of this project are to determine the optimal dose and dosing schedule for the protective drugs and to determine the requirement of neuronal calcium sensor 1 (NCS1) in the development of chemotherapy-induced peripheral neuropathy (CIPN).
Collaborators: Barbara Ehrlich and Paul Eder.
Michael Robek, PhD: The purpose of this project is to develop a safe and effective therapeutic vaccine to cure chronic hepatitis B virus (HBV) infection and prevent the complications such as liver cancer that occur as a consequence of this disease.
Collaborator: Michael Rose
Roy Decker, MD, PhD, Associate Professor of Therapeutic Radiology and a member of Yale Cancer Center's Radiotherapy and Radiobiology Research Program, has been selected to represent SWOG on the Brain Malignancies Steering Committee (BMSC). The goal of the BMSC is to promote the best clinical and translational research for patients with brain cancer by critically reviewing phase II and phase III clinical trial concepts.
S. David Hudnall, MD, Professor of Pathology and Laboratory Medicine and a member of Yale Cancer Center's Molecular Virology Program, recently published a textbook through Springer entitled, "Viruses and Human Cancer." The book provides a comprehensive review of the seven currently known human tumor viruses and their associated cancers.
Sigma Theta Tau International (STTI), the Honor Society of Nursing, has announced its 2014 Nurse Researcher Hall of Fame inductees, which includes Ruth McCorkle, PhD, RN, FAAN, Assistant Director of Psychosocial Oncology Research at Yale Cancer Center, Florence Schorske Wald Professor
of Nursing, and Professor of Epidemiology. The induction ceremony will take place during STTI's 25th International Nursing Research Congress in Hong Kong, July 24-28, 2014.
Abhijit Patel, MD, PhD, Assistant Professor of Therapeutic Radiology and a member of our Radiobiology and Radiotherapy Program, has been awarded an Early Detection Research Award from the LUNGevity Foundation. The award is for $200K over 2 years and will support his research into "Detection of early-stage lung cancers via tumor DNA in blood."
Roy S. Herbst, MD, PhD, Chief of Medical Oncology, Ensign Professor of Medicine, and Associate Director of Translational Medicine, was awarded the Alvin S. Slotnik Lecture Award for notable contributions to cancer research from Dana-Farber/Brigham and Women's Cancer Center.
Susan Mayne, PhD, was selected for the inaugural Excellence in Education Award from the Society for Epidemiologic Research. The Excellence in Education award is presented to an individual who has made substantial contributions to the field of epidemiology through mentoring, training, and/or teaching.
Valentina Greco, PhD, Assistant Professor of Genetics and Dermatology and a member of our Molecular Virology Program, has been selected as the recipient of the American Society for Cell Biology Women in Cell Biology 2014 Junior Award for Excellence in Research Award. The award recognizes exceptional scientific contributions to cell biology, development of a strong independent research program, and exhibiting the potential for continued scientific achievement and leadership.
Alfred L.M. Bothwell, PhD, Professor of Immunobiology and a member of our Immunology and Immunotherapy Program, has received the Inaugural Wendy U. and Thomas C. Naratil Pioneer Award from Women's Health Research at Yale to support his project to study "Personalized Medicine" for the Most Lethal Endometrial Cancer. Dr. Bothwell will look for new, more effective treatments for uterine serous cancer, a particularly aggressive form of endometrial cancer that accounts for 10 percent of endometrial cancer cases, but is responsible for nearly 40 percent of endometrial cancer deaths.
Andrew T. Putnam, MD, Assistant Professor of Medicine (Medical Oncology) and a member of Smilow Cancer Hospital at Yale-New Haven's Palliative Care Medicine Program, was awarded his certification for completion of the 2013-2014 Medical Education Fellowship through the Yale School of Medicine's Teaching and Learning Center at the Yale Medical Education conference. Dr. Putnam also presented a poster at the conference entitled, "Faculty Development to Acquire Effective Communication Skills: Tailoring our Communication to Best Suit our Patients."
Simon Kim, MD, MPH, Assistant Professor of Urology, received a Career Development Award from the Conquer Cancer Foundation at this year's ASCO meeting. The three-year, $200,000 grant will support his research project on "National Trends in Active Surveillance for Prostate Cancer and Barriers to its Use."
Yale School of Medicine presented The Charles W. Bohmfalk Prize for teaching in the basic sciences to Susan Baserga, PhD, MD, Professor of Molecular Biophysics and Biochemistry, of Genetics, and of Therapeutic Radiology, and a member of our Genetics and Genomics Research Program.
Douglas E. Brash, Professor of Therapeutic Radiology and a member of our Radiobiology and Radiotherapy Program, will be awarded the 2014 Finsen Medal of the International Union of Photobiology. The IUP Congress presents the medal, recognizing lifetime achievement in photobiology, every five years. It commemorates Niels R. Finsen, recipient of the 1903 Nobel Prize in Physiology or Medicine for his studies on phototherapy of cutaneous tuberculosis. Dr. Brash's laboratory has elucidated many of the steps through which sunlight causes skin cancer.
Alanna Schepartz, PhD, Milton Harris Professor of Chemistry and Professor of Molecular, Cellular & Developmental Biology, and a member of Yale Cancer Center's Developmental Therapeutics Program, has been elected into the National Academy of Sciences.
David Schatz, PhD, Professor of Immunobiology and of Biophysics and Biochemistry and a member of Yale Cancer Center's Immunology and Immunotherapy Program, has been elected in to the American Academy of Arts and Sciences.
Roy Herbst, MD, PhD participated in the National Forum on the Future of Health Care at the National Press Club in Washington, DC last week and presented on Research in the Age of Personalized Medicine: Lung Cancer Master Protocol.
Daniel Petrylak, MD presented a poster during the 29th Annual EAU Congress in Stockholm, which was awarded a best poster award during the meeting. A phase 2 trial of prostate specific membrane antigen antibody drug conjugate (PSMA ADC) in taxane-treated metastatic castration-resistant prostate cancer (MCRPC).
Narendra Wajapeyee, MD has published Cancer Genomics and Proteomics: Methods and Protocols, as part of the Methods in Molecular Biology Book Series.
Cary Gross, MD has been awarded a 3-year grant from the American Cancer Society totaling $592,000 to study cancer disparities. His study will provide a timely assessment of personalized cancer care patterns and their impact on cancer equity, and identify potential leverage points to ensure optimum access to this novel and increasingly important aspect of cancer care.
Barbara Burtness, MD has recently published Molecular Determinants of Head and Neck Cancer in the Current Cancer Research Series (Series Editor: Wafik El-Deiry, MD).
Leah Ferrucci, PhD received the Best Poster Award at the American Society of Preventive Oncology meeting for her poster, "Ultraviolet radiation-related behaviors among young people after a diagnosis of melanoma or basal cell carcinoma."
The American Academy of Orthopaedic Surgeons (AAOS) today presented the 2014 William W. Tipton Leadership Award to Gary E. Friedlaender, MD.The Tipton Leadership Award recognizes Academy members who have demonstrated outstanding leadership qualities that have benefitted the orthopaedic community, patients, and/or the American public.
Alfred Bothwell, PhD, a member of the Cancer Immunology Program, has received an RO1 grant entitled "Regulatory T cell Control of Intestinal Tumorigenesis" from the National Cancer Institutes. Dr. Bothwell's research will look to give important mechanistic insight into the specific inflammatory molecules that can compromise cells of the immune system.
The Connecticut Academy of Science and Engineering announced that six members of Yale Cancer Center were elected to membership on the basis of their distinguished contributions to science or engineering. The YCC members are Ronald Breaker, Lynn Cooley, Daniel DiMaio, James Duncan, Theodore Holford, Stephanie O'Malley, and Patrick Sung.
Kenneth Williams, PhD has received a $25,000 Yale School of Public Health Ovarian Cancer Pilot Research Grant, which is funded by the Tina Brozman Foundation, for one year to support his project, "Targeted Serum Proteome Assay for Early Detection of Ovarian Cancer.
Brian Shuch, MD has been named to the NCI/NIH PDQ Cancer Genetics Editorial Board and their Kidney Cancer Working Group.
Dr. Andrea Silber has received a $20,000 grant from the Breast Cancer Alliance to support community outreach and education in the New Haven community. Dr. Silber will use the funds to help provide breast cancer education and increase clinical trial participation at our Care Center at the St. Raphael Campus.
The National Academy of Inventors (NAI) has elected Mark Saltzman, PhD, Goizueta Foundation Professor of Biomedical Engineering, Chemical & Environmental Engineering, & Physiology, and a member of the Developmental Therapeutics Program, as a 2013 NAI Fellow.
Congratulations to Melissa Durand, MD, Veerle Bossuyt, MD, Christos Hatzis, PhD, and Lajos Pusztai, MD, DPhil - each of whom received a Lion Heart grant to support their breast cancer research work.
William K.C Cheung, PhD, a post doctoral associate in Don Nguyen's lab, was awarded a $100k grant from Uniting Against Lung Cancer to support his project titled: "Treating metastasis by differentiation therapy: Identifying druggable pathways."
Rick Lifton, MD, PhD, a member of Yale Cancer Center's Genetics and Genomics Program, was named one of six winners of the 2014 Breakthrough Prize in Life Sciences.
This $3 million prize was developed by Sergey Brin, Mark Zuckerberg, Jack Ma, and Yuri Milner, together with their families, to honor the most accomplished life scientists.
Craig M. Crews, PhD, a member of Yale Cancer Center's Developmental Therapeutics Program, has been named CURE Entrepreneur of the Year for founding two biotechnology startups in Connecticut based on discoveries made in his laboratories
Rogerio Lilenbaum, MD, Chief Medical Officer of Smilow Cancer Hospital, has been named Editor of the Brazilian edition of the Journal of Clinical Oncology. Rogerio will select appropriate articles from the US edition of the journal for inclusion in the Brazilian edition and oversee the quality of the translation.
Bonnie Gould Rothberg, MD, PhD, MPH has been awarded a 2014 Patterson Trust Award to support her research project, "Germline Genetic Variation in T2a-T4b Cutaneous Melanoma Prognosis." Her research will study, using Ion Torrent Next-Generation DNA sequencing, whether a genetic variation found within 100 genes already known to be important to melanoma growth can predict recurrence among 920 Stage II/IIIA melanoma patients who all received SLNB and clinical follow-up within the Yale Melanoma Unit from 1997-2012.
Katerina Politi, PhD received the 2013 Lynne Tarnopol Award from the Lung Cancer Research Foundation to support her work titled "The Influence of Tumor Cell-of-Origin and Heterogeneity on Acquired Resistance to Targeted Therapies in Cancer." The award provides $50K for research on this project. The Lynne Tarnopol Award is given in honor of a long-standing supporter and advocate for the LCRF and recognizes an outstanding research proposal from a young woman scientist. Dr. Politi is the inaugural recipient of the award, formally recognizing the pivotal accomplishments and contributions of women scientists in the field of lung cancer research.
Yang Zhou, a doctoral student in the lab of Melinda Irwin, PhD, has received 1st prize in the American Institute for Cancer Research Abstract Competition "In Training" category for students, postdocs, and fellows. She will present her poster on BMI, Physical Activity and Mortality in Women Diagnosed with Ovarian Cancer: Results from the Women's Health Initiative at the Obesity and Cancer Section Meeting in Atlanta on November 13th and receive her award.
Narendra Wajapeyee, PhD, Assistant Professor of Pathology and a member of Signal Transduction Program, has received two awards. The National Lung Cancer Partnership and the United Against Lung Cancer Foundation jointly funded the first award in the amount of $108,000 to support his research on targeting p53-mutant lung cancers. The Melanoma Research Foundation also provided him with $100,000 to support his research to identify driver alterations in melanoma funds.
Qin Yan, PhD was awarded a Career Development Award from the Department of Defense Peer Reviewed Cancer Research Program to support his research on "Targeting Epigenetic Regulator JARID1B in Malignant Melanoma." The major goal of his project is to determine the effects of Jarid1b loss on melanoma formation and progression using the Braf/Cdkn2a mouse melanoma model. The total cost is $399,600 over two years.
James Hansen, MD has been named a 2013 Research Scholar grant recipient from the Radiological Society of North America (RSNA). Dr. Hansen will use the grant funds to support his research to "Target Glioblastoma with a Lupus Autoantibody." The $150,00 grant will fund his research project for two years.
OncLive has named the 2013 Giants of Cancer Care in 12 different disease areas. Dr. Thomas Lynch was chosen for lung cancer and Dr. Vincent DeVita was named for lymphoma by a national advisory panel of oncology educators, clinicians, and researchers.
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Tae Hoon Kim, PhD a member of the Genetics and Genomics Research Program, has recently received two grants to support his research efforts. The Connecticut Stem Cell Research Fund has provided him with $750,000 to study "Pluripotency and Heterochromatin Topology" and the National Institute of Allergy and Infectious Diseases at the NIH has awarded him with an R21 to research "Nuclear, Genomic and Molecular Regulation of Type I Interferon Transcription."
Meena Moran, MD has been named Co-Chair Elect for the 2014 Breast Cancer Symposium and will Chair the Fellows, Residents, and Junior Faculty Tract of this year's meeting in September.
Frank Slack, PhD, and Joanne Weidhaas, MD, PhD, were awarded a grant from LUNGevity for their work on the KRAS-variant. They identified the KRAS-variant as a predictive marker for lung cancer therapy. The investigators were awarded $500,000 over two years for a collaborative effort between Yale Cancer Center and MD Anderson Cancer Center.
Gerald Shadel, PhD has received a $200,000 grant from the state of Connecticut through the Stem Cell Research Fund to fund "Testing the oxidative stress theory of Ataxia-Telangiectasia pathology using induced pluripotent stem cells."
Three Yale Cancer Center members have received grants from the state of Connecticut through the Stem Cell Research Fund to support their research initiatives.
Zhong Yu: Hypoxia and Maintenance of Human Cancer Stem Cells
Nancy Ruddle: The Role of Adipocyte Stem Cell in Lymphatic Vessel Differentiation
Haifan Lin: Continued Service and Technology Development at the Yale Stem Cell Center Cores
Yale Cancer Center members, Ryan Jensen and Akiko Iwasaki, have both received 2013 pilot grants from the Women's Health Research at Yale Program.
The American Orthopaedic Association recently awarded the Distinguished Contributions to Orthopaedics Award to Gary Friedlaender, MD, Chairman of the Department of Orthopaedics and Clinical Leader of the Sarcoma Program at Smilow Cancer Hospital. The award is presented to one physician annually for their contributions to the field of Orthopaedics and patient care.
The David S. Fischer, MD annual award for outstanding teaching & mentoring offellows in Hematology was awarded to Thomas P. Duffy, MD.
The David S. Fischer, MD annual award for outstanding teaching & mentoring of fellows in Medical Oncology was awarded to Daniel Morgensztern, MD.
The David S. Fischer, MD annual award for outstanding teaching & mentoring of fellows in Medical Oncology & Hematology was awarded to Michal G. Rose, MD.
A Medical Oncology & Hematology Fellowship Program annual award for Outstanding Fellow in Research was awarded to both Hong Zheng, MD, PhD and Vamsidhar Velcheti, MD.
Roy S. Herbst, MD, PhD has been named the Ensign Professor of Medical Oncology by the Yale Corporation. This is a well-deserved honor for Roy, who is nationally recognized for his leadership in lung cancer treatment and research.
Ellen Matloff, MS, Director of Cancer Genetic Counseling, recently published Cancer Principles and Practices of Oncology: Handbook of Cancer Clinical Genetics. The guidebook allows clinicians to search under each disease site for the hereditary cancer syndromes relevant for his/her patient's cancer. The book is available through Lippincott Williams & Wilcott.
Congratulations to Mehmet Kocoglu, a third year medical oncology-hematology fellow, who received a Young Investigators Award from the Conquer Cancer Foundation on Sunday during the ASCO Awards Program. The funding will support Mehmet's research into microvesicles in multiple myeloma
Yale immunobiologist Akiko Iwasaki, PhD, a member of the Yale Cancer Center Molecular Virology Research Program, has been selected as a Howard Hughes Medical Institute (HHMI) investigator, one of the most prestigious designations in biomedical science. She was one of 27 of the nation's top researchers to receive this honor.
Dr. Erin Hofstatter was featured in the Spring/Summer issue of Centerpoint Newsletter.
The Connecticut Department of Public Health and Senator Joseph Crisco announced that 7 members of Yale Cancer Center have been awarded 2013 Biomedical Trust Fund recipients. Drs. Mamula, Nathanson, Regan, Stern, and Yan's projects are directly related to our Research Program objectives and are listed as follows:
Mark J. Mamula, PhD was awarded $216,043 to analyze the antibody profile of trastuzumab-treated patients before, during, and after treatment. This work will determine the clinical efficacy of trastuzumab treatment for breast cancer and predict potential cardiotoxicity.
Michael Nathanson, MD, PhD was awarded $367,401 to support his study into whether and how lipid accumulation alters the mechanisms of Ca2+ release in the nucleus of liver cells that lead to uncontrolled cell proliferation and liver tumor progression.
Lynne Regan, PhD was awarded $284,739 for her project to study the molecular effects of epigenetic histone modifications to determine the energetic and mechanistic consequences of these modifications on disease.
David F. Stern, PhD was awarded $424,466 for his project to identify combinations that are effective on lung cancers driven by specific gene mutations using a tiered single agent and combinatorial two-agent screen of a curated panel of conventional and molecularly targeted anti-cancer agents.
Qin Yan, PhD was awarded $420,488 for his project to dissect the roles of histone demethylase RBP2 in breast cancer metastasis.
Stephanie Scarmo, a PhD student in Chronic Disease Epidemiology, has had her publication, Skin Carotenoid Status Measured by Resonance Raman Spectroscopy as a Biomarker of Fruit and Vegetable Intake in Preschool Children (European Journal of Clinical Nutrition 2012;66:555), selected to be featured in the NCI's electronic newsletter, Nutrition Frontiers. Nutrition Frontiers is a quarterly publication of the Nutritional Science Research Group (NSRG), NCI, NIH.
Scott Gettinger, MD is presenting at the 19th Annual Network of Oncology Clinicians and Researchers (NOCR) meeting this weekend. The topic of his presentation will be Immunotherapy and NSCLC.
Susan Mayne, PhD, is delivering an NIH-wide lecture next week, in their series "Stars in Nutrition and Cancer." She will discuss Micronutrients and Cancer Prevention: A Complex World.
Renowned Yale immunologist Ruslan Medzhitov has been awarded the inaugural Lurie Prize in the Biomedical Sciences from the Foundation for the National Institutes of Health (FNIH). The award, which honors early-career researchers whose findings have advanced basic biomedical science, was given to Medzhitov for his groundbreaking discoveries about the workings of the innate immune system, the body's first line of defense against bacteria and viruses.
The St. Baldrick's Foundation recently announced that Nina Kadan-Lottick, MD has been named the TeamBrent-St. Baldrick's Scholar. The $230,000 award will support Dr. Kadan-Lottick's research focusing on survivorship and her studies on how cancer therapy affects a child's growing brain and learning.
Nita Maihle, PhD is the recipient of the Albert Einstein College of Medicine 2013 Distinguished PhD Alumna Award in recognition of her outstanding professional accomplishments and contributions to the biomedical community.
The American Urological Association will award the Victor A. Politano Award to Toby C. Chai, MD, in recognition of outstanding work in the treatment of urinary incontinence and innovations in bladder research. The award will be presented to Dr. Chai at the Association's annual meeting in May.
Pietro De Camilli, MD, Eugene Higgins Professor of Cell Biology, and March Hochstrasser, PhD, Eugene Higgins Professor of Molecular Biophysics and Biochemistry, have been named fellows of the American Association for the Advancement of Science (AAAS). Both Dr. De Camilli and Dr. Hochstrasser are members of the Yale Cancer Center Signal Transduction Program
David A. Spiegel, PhD has been awarded $3.6 million from the U.S. Department of Defense as one of three 2012 recipients of the Era of Hope Scholar Award. A member of the Yale Cancer Center Developmental Therapeutics Program, Dr. Spiegel's research project intends to develop a technology platform that will enable the creation of molecules that can distinguish between healthy and diseased cells, with a focus on breast cancer cells.
Dr. Jordan Pober, a member of the Yale Cancer Center Cancer Immunology Program, has been named the inaugural Bayer Professor of Translational Research at Yale School of Medicine. Dr. Pober serves as director of the Human and Translational Immunology Program at Yale School of Medicine and is vice-chair of the Department of Immunology's Section of Human and Translational Immunology.
Xiaoling Song, PhD, a postdoc in the lab of Katie Politi, has been awarded a 2 year, $100,000 grant from Uniting Against Lung Cancer to support her project, "The Role of ERBB2 and ERBB3 in Resistance to Tyrosine Kinase Inhibitors in EGFR Mutant Lung Cancer."
Michael DiGiovanna, MD, PhD has received a $50,000 grant from the Connecticut Breast Health Initiative to fund his research into Combination Targeting of IGF-1 Receptor and HER2 in Breast Cancer. This is the fourth consecutive year Dr. DiGiovanna has received funding from the CT Breast Health Initiative to support his research.
Dr. Wendell Yarbrough was featured in the Fall/Winter issue of Centerpoint Newsletter.
Andrea Silber, MD was appointed and elected to the Connecticut Cancer Partnership Board of Directors during their annual meeting. Her term will run for two years. Dr. Silber joins other Yale members on the Board, including Brenda Cartmel and Renee Gaudette.
Andrea Silber, MD and her team at the Smilow Cancer Care Center at the Saint Raphaels Campus were recently applauded by the Connecticut Department of Public Health (CT DPH) for their screening efforts through the Breast and Cervical Cancer Early Detection Program and the WISEWOMAN Program, both funded by the CDC through the CT DPH. They screened 941 women in the first six months of this year (through July 1) and have screened over 4,000 women since the inception of the programs. The two programs target uninsured and underinsured women in Connecticut who are between 40-65 years old.
Daniel C. DiMaio, MD, PhD, Roy S. Herbst, MD, PhD, and Thomas J. Lynch, Jr., MD have all been appointed Honorary Professors of the University College London in the Cancer Institute by Chris Boshoff, Director of the Cancer Institute at UCL.
Rong Fan, PhD, a member of the Yale Cancer Center Signal Transduction Research Program, has been awarded a 2012 Packard Fellowship in Science and Engineering. The Fellowship is one of the most prestigious awards to be given to early career scientists in the nation, and provides $875,000 in research funding over 5 years. Dr. Fan will use the funding to study genome-scale epigenetic mapping of single cells with the ultimate goal of creating a high-throughput microfluidic chip for genome-scale epigenetic mapping of single tumor cells from patients
Raymond Russell, MD gave a lecture at the American Society of Nuclear Cardiology Annual Meeting in September. His presentation was entitled, "Cardiovascular toxicities of molecularly-targeted chemotherapeutic agents.
Don Nguyen, PhD received an R01 from the National Cancer Institute for his project, "A Novel Lineage Specific Metastasis Suppressor Pathway in Lung Cancer." The 5-year grant for $1,129,207 will study how fundamental molecular circuits that control airway development are re-wired during lung adenocarcinoma metastasis. Don is a member of the Signal Transduction Research Program.
Valentina Greco, PhD received an R01 grant from the National Institutes of Health for her project, "Live Imaging of Skin Regeneration." The 5-year grant for $1,872,188 will study the cellular and signaling mechanisms that govern tissue regeneration in the hair follicle stem cell niche by live imaging. Valentina is a member of the Signal Transduction Research Program.
Meena Moran, MD was an invited presenter for Harvard Medical School's Breast Center Grand Rounds this week. Dr. Moran presented "Why the differences in African American vs. White breast cancer outcomes? Putting together the pieces of breast health disparities"
David Fischer, MD, will receive the Richard Blumenthal Patient Advocate for Life Award from the Connecticut Hospice Dr. Fischer helped to found CT Hospice back in 1974; it is the first Hospice in the country. He continues to be a member of their Professional Advisory Committee.
John Roberts, MD, received the Harry Hines Award from the NCI Community Clinical Oncology Program (CCOP) at their annual meeting. The award is the equivalent to the CCOP Principal Investigator of the Year, selected by NCI staff.
Yale Cancer Center has been accepted into the Lung Cancer Mutation Consortium (LCMC) as a result of an application and efforts by Katerina Politi, PhD and Roy Herbst, MD, PhD. The LCMC is composed of a group of 14 Cancer Centers across the country that came together in 2009 to test advanced lung adenocarcinomas for genetic alterations in genes known to drive the formation of lung tumors. Based on the genetic characteristics of individual tumors, patients are then matched to clinical trials of targeted agents. The LCMC recently solicited applications from institutions to participate and Yale was ranked amongst the top 5 new institutions out of 32 applicants and was invited to join the Consortium.
Joan Steitz, PhD, a member of the YCC Molecular Virology Program, has received two awards for her contributions to science. She recently received the Pearl Meister Greengard Prize of Rockefeller University, which recognizes outstanding achievements of women scientists. Also, Vanderbilt University School of Medicine will present Dr. Steitz with the 2012 Vanderbilt Prize in Biomedical Science for her work with RNA and her commitment to advancing the careers of women scientists.
Dr. Herta Chao has been promoted to Associate Professor of Medicine (Medical Oncology). Dr. Chao is a member of our Developmental Therapeutics Research Program and cares for patients at the West Haven VA Cancer Center.
Dr. Brenda Cartmel has been awarded an R03 grant from the National Institutes of Health to study the effect of exercise on cortisol dysregulation in ovarian cancer survivors. The study will explore whether a 6-month home-based exercise intervention will alter the diurnal cortisol patterns in ovarian cancer and the association between diurnal cortisol patterns and quality of life, depression, and fatigue in ovarian cancer survivors.
Dr. Michael DiGiovanna received a grant from the Connecticut Breast Health Initiative to fund his study on combination targeting of the IGF-1 receptor and HER2 in breast cancer. This is the fourth consecutive year that Dr. DiGiovanna has received funding from the program.
Cynthia Waddock has joined the Yale Cancer Center billing office as a Certified Professional Coder - Apprentice (CPC-A).
Eileen Dehm, RN and Matthew Burke, APRN, members of the Thoracic Oncology Program care team, will present "From Clinical Trials to Commercial Use: Oncology Drugs and the Oncology Nurse Coordinator Role in a Clinical Setting" during a poster presentation at the 2012 Annual Evidence Based Practice Conference sponsored by the Connecticut Nursing Research Alliance Review Committee.
Stacey Scirocco has been named Associate Director of the Office of Protocol Review and Monitoring for Committee Administration for Clinical Research Services at Yale Cancer Center. Stacey returns to Yale Cancer Center from the Yale Center for Clinical Investigation and will work closely with Susan Anderson.
The Association of Residents in Radiation Oncology (ARRO) named Bryan Chang, Assistant Professor of Therapeutic Radiology and a member of the Radiobiology and Radiotherapy Research Program, Educator of the Year for the 2011-12 academic year.
Roy S. Herbst, MD, PhD has been elected as one of four new Translational Science Representatives serving on the Thoracic Malignancy Steering Committee (TMSC) for the National Cancer Institute (NCI).
Peter Glazer and Regina Hooley have been awarded grants through the Women's Health Research at Yale program. Dr. Glazer's study will focus on an antibody, 3E10, and its ability to improve the efficacy of chemotherapy and radiation to treat breast and ovarian cancers. Dr. Hooley will use the grant funding to review the results of breast ultrasound screening in Connecticut since 2009 to determine its usefulness in screening women for breast cancer.
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Two Yale Cancer Center members were recently honored with awards from the Yale School of Medicine. Farzana Pashankar received the Department of Pediatrics Teaching Award and Kavita Dhodapkar recently the Department of Pediatrics Junior Faculty Research Award.
Yale Cancer Center members Valerie Horsely, Natalia Ivanova, Frank Slack, and Julie Ann Sosa have received grants from the Connecticut Stem Cell Fund to support research projects and to seed new ideas in stem cell research for cancer.
Alfred Lee, MD, PhD, received the Teacher of the Year Award from the Department of Internal Medicine for his leadership in the Traditional Internal Medicine Residency Program.
Diane Krause, MD has been selected to participate in a prestigious year-long leadership training program for women in medicine called Executive Leadership in Academic Medicine (ELAM) at Drexel University.
Julie Ann Sosa, MD has been named to the Society for Surgical Oncology Steering Committee directed to create the Surgical Oncology Self-Assessment Program (SOSAP), which is modeled after the American College of Surgeon's SESAP program. Dr. Sosa will represent the endocrine/head and neck disease sites.
Zhiwei Hu, PhD is the Editor-in-Chief of The Journal of Analytical & Bioanalytical Techniques and editor/editorial board member of The Journal of Immune Based Therapies, Vaccines and Antimicrobials, The Journal of Solid Tumors, and Advances in Breast Cancer Research
Valentina Pirazzoli, a postdoctoral fellow in the Politi lab, has received a fellowship renewal from the American Italian Cancer Foundation. Valentina's project is entitled, Uncovering mechanisms of resistance to new combinations of targeted therapies using mouse models of EGFR mutant lung adenocarcinoma.
Congratulations to the following Yale Cancer Center/Smilow Cancer Hospital physicians who were named to the 2012 New York Magazine Best Doctors List: Masoud Azodi, Jean Bolognia, John Colberg, Frank Detterbeck, Andrew Duffy, Richard Edelson, Sukru Emre, Roy Herbst, Howard Hochster, Silvio Inzucchi, John Kveton, David Leffell, Walter Longo, Pasquale Patrizio, John Persing, Richard Peschel, Carrie Redlich, Kenneth Roberts, Clarence Sasaki, Gordon Sze, Robert Udelsman, Jeffrey Weinreb, and Lynn Wilson.
Rebecca Sipples, Marianne Davies, Amanda Reid, and Emily Duffield recently published chapters in a new resource for patients with lung cancer, Lung Cancer Choices.
Roy Herbst will be hosting a Briefing on Capitol Hill with AACR on Tuesday, June 12 on "The Science Behind Tobacco Control: How Research Informs Policy to Save Lives and Money." Senator Richard Blumenthal is also scheduled to give remarks.
Kelly Chacon, a student in the DiMaio Laboratory, graduated from Yale College in May with an Intensive Bachelor of Science in Biology degree with distinction in the major. She was named the recipient of the Edgar J. Boell Prize, which is awarded annually to a Yale College senior for excellence in biology and senior research. The title of her senior research project was Unintelligent Design of an Oncoprotein. She will continue this work in the DiMaio laboratory next year.
Tom Magaldi obtained his PhD degree for research done in the DiMaio Laboratory concerning the interactions of tumor viruses with their host cells. His doctoral dissertation, Genetic Analysis of SV40 Receptor Usage, received the Outstanding Thesis Award from the Department of Genetics. This summer, he will begin a postdoctoral fellowship at the National Institutes of Health.
Roy Herbst has been named Vice-Chair of the American Association for Cancer Research's Science Policy and Legislative Affairs Committee (SPLAC). The committee serves as AACR's principal means for devising and implementing strategies to influence important biomedical research-related public policy issues. Dr. Herbst has been an active member of the committee for the last several years and will continue to serve as the Chairman of the AACR Task Force on Tobacco and Cancer.
Four physicians from the Smilow Cancer Hospital Cancer Care Centers were named to Connecticut Magazine's 2012 Top Doc's list. Congratulations to Samuel Bobrow, Victor Chang, Martin Katz, and Kert Sabbath.
Suzanne Evans was an invited lecturer at the New England Society for Radiation Oncologists in April and presented "After the Error: Ethical Issues in Medical Error Disclosure." Dr. Evans is also scheduled to present at the New England Chapter of the American Association of Physicists in June.
Jason Wilken, a trainee in Yale's Komen-funded 'Racial Disparities in Breast Cancer' Post-graduate Training Program, has been appointed as one of only 83 new Epidemic Intelligence Service (EIS) Officers with the Centers for Disease Control and Prevention (CDC) effective July 2012. Nita Maihle in the Department of Obstetrics, Gynecology & Reproductive Sciences, mentors Dr. Wilken.
Dan Avi Landau received a three-year postdoctoral fellowship award from the American Cancer Society to support his research to reconstruct genotype-phenotype maps in chronic lymphocytic leukemia.
Dr. Peter Schulam was featured in the Spring/Summer issue of Centerpoint Newsletter.
Vamsidir Velcheti, a third year fellow, is a recipient of the 2012 ASCO Young Investigator Award. This one-year, $50,000 award is to support physicians during the transition from fellowship to faculty appointment. Under the mentorship of David Rimm and Roy Herbst, Dr. Velcheti will evaluate the prognostic and predictive value of PD-1 ligand expression in non-small cell lung cancer by AQUA, an automated quantitative immunofluorescence-based assay.
Anne Chiang has been invited to serve on the ASCO Quality of Care Committee. Her participation on the committee will begin during the annual meeting for ASCO in June.
Dr. Ronald Salem has been awarded the 2011 Leffell Prize for Clinical Excellence at Yale School of Medicine. Each year, the award recognizes a faculty member who best exemplifies clinical expertise, a commitment to teaching and the highest standards of care and compassion for patients. Dr. Salem has been a member of Yale Cancer Center and an oncology surgeon at Yale for over 20 years.
Nicholas Theodosakis, a third year MD/PhD student in the lab of Marcus Bosenberg, has received a $10,000 scholarship award from the Joanna M. Nicolay Melanoma Foundation.
Don Nguyen, PhD, Assistant Professor of Pathology and a member of the Yale Cancer Center Signal Transduction Research Program, has been awarded a 2012-2014 Young Investigator Award from the International Association for the Study of Lung Cancer (IASLC) to support his research on metastatic lung adenocarcinoma. Dr. Nguyen will receive $80,000 over two years.
Seth Herzon, PhD, Assistant Professor of Chemistry and a member of the Yale Cancer Center Developmental Therapeutics Research Program, has been awarded a 2012 Sloan Research Fellowship, given to early career scientists whose achievements identify them as rising stars. Dr. Herzon will receive a $50,000 grant to further his research.
A committee of medical peers has named Richard L. Edelson, MD, Chair and Aaron and Marguerite Lerner Professor of Dermatology, one of three National Physicians of the Year. The committee, assembled by the firm Castle Connolly Medical, chose Edelson from among 150 nominees for the award. He will receive the Clinical Excellence Award during a ceremony on Monday, March 26.
James Munro, a post-doctoral fellow in the laboratory of Walther Mothes, has received a grant from the Cancer Research Institute to utilize state-of-the-art imaging technologies to visualize HIV envelope protein (Env) molecules-the primary target for anti-HIV antibodies generated by the immune system. The grant is for three years of support, for a total of $160,000.
Srini Koduru, a postdoc in the laboratory of Madhav Dhodopkar, has received a Scholar-in-Training award from the American Association for Cancer Research for his abstract, "Induction of activation-induced cytidine deaminase (AID) by dendritic cells leads to genomic instability in human myeloma." He will be presented with the award at this year's annual meeting in April.
Narendra Wajapeyee, PhD, a member of the Yale Cancer Center Signal Transduction Research Program, has received a grant award from the Elsa U. Pardee Foundation for $100,000 for one year to support his project entitled, "Pre-Clinical Evaluation of IGFBP7 as a Lung Cancer Therapeutic."
Faye Rogers, PhD, has received the Norma Lies Mitchell Exceptional Project Grant from the Breast Cancer Alliance to support her research project, "Gene-targeted Apoptosis as a Therapeutic Strategy for HER2-positive Breast Cancer."
Valentina Greco, PhD, is the recipient of a 2012 Research Scholar Grant from the American Cancer Society to support her project Stem Cell Deregulation During Tumor Regression. She will receive $720,000 per year for four years to study and understand stem cell dynamics during tumor regression using a squamous cell carcinoma as a model system.
Leslie Blatt, APRN, was awarded the 2011 Safe Passage Award for Outstanding Clinical Care from the Connecticut Coalition to Improve End-of-Life Care at their annual meeting. The award is presented to a clinician in recognition of outstanding clinical contributions to the field of end-of-life care.
Janet Brandsma, PhD, and Malini Harigopal, MD, Assistant Professor of Pathology, received a $50,000 grant from the American Society of Cytology Foundation to study HPV16 DNA Methylation Frequency for the Improved Triage of ASCUS.
Don Nguyen, PhD, has been awarded a Young Investigator Research Grant from the National Lung Cancer Partnership.
Tian Xu, PhD, and Ruslan Medzhitov, PhDwere elected 2011 fellows of the American Association for the Advancement of Science There are 17 YCC members who are fellows of the AAAS.
The Breast Center at Smilow Cancer Hospital at Yale-New Haven completed the NAPBC survey process and has been awarded a three-year full accreditation. Learn more>>
Yung-Chi Cheng,PhD, was awarded a PO1 Grant from the NCI to explore PHY906, a 4-herb Chinese medicine in a clinical phase II setting as adjuvant therapy for Irinotecan based chemotherapy in advanced colon cancer. The grant is titled "Chinese Herbal Medicine as a Paradigm for Cancer Chemotherapy."
Dr. Stuart Seropian was featured in the Summer/ Fall issue of Centerpoint Newsletter.
June 10, 2011
Ruslan Medzhitov, PhD, a member of the Yale Cancer Center Cancer Immunology Program, is one of three scientists awarded the prestigious Shaw Prize in Life Science and Medicine for 2011. Medzhitov has made groundbreaking contributions to the understanding of innate immunity, which provides immediate defense against infection.
Meena Moran, MD, has recently been nominated to join the editorial board of the Journal of Clinical Oncology (JCO). Dr. Moran is an Associate Professor of Therapeutic Radiology and a member of the Yale Cancer Center Radiobiology & Radiotherapy Research Program.
Anthony Koleske, PhD and Titus Boggon, PhD, both members of the Yale Cancer Center Signal Transduction Program, are the recipients of a 2011 Women's Health Research at Yale Pilot Grant, co-funded by Yale Cancer Center. Their research will focus on new drug development to selectively target breast cancer metastasis.
May 27, 2011
Dr. Vincent T. Devita, Jr. is co-editor on three recently published books: the 9th edition of the most popular cancer text in the world Cancer: Principles & Practice of Oncology, Primer of the Molecular Biology of Cancer, and Annual Advances in Oncology, Volume 2.
Abhijit Patel, PhD, Assistant Professor of Therapeutic Radiology, has been awarded a Junior Faculty Career Research Training Award from the American Society for Radiation Oncology (ASTRO). The award totals $200,000 over two years and will support his research to develop tumor-derived DNA in the blood as a cancer biomarker. Dr. Patel had received a Yale Cancer Center Pilot Award to initiate the project and will continue his work with the ASTRO funding.
Dr. Anees Chagpar and Dr. Francine Foss have been selected as two of 21 mentors nationwide for the 2011 ASCO IDEA (International Development and Education Award) Program. Following next week's ASCO meeting, both Dr. Chagpar and Dr. Foss will host a mentee from India at Yale Cancer Center and Smilow Cancer Hospital from June 8-10. Dr. Chagpar will host Anand Kumar Mishra from CSM Medical University and Dr. Foss will mentor Indranil Ghosh from ARI Hospitals.
Qin Yan, PhD and Tae Kim, PhD were selected as Stewart Fellows and will receive two years of funding to support their cancer research, totaling $150,000 per faculty member. The Alexander & Margaret Stewart Trust is a charitable foundation supporting nonprofit organizations researching, treating, and preventing cancer and pediatric illnesses.
May 13, 2011
Nita Maihle, PhD, Professor of Obstetrics/Gynecology and Pathology, Beth Jones, PhD, MPH, and Jason Wilken, PhD were awarded a $270,000 grant from Susan G. Komen for the Cure. The award will be used to study healthcare disparities in Hispanic women with breast cancer, and will support two trainees from backgrounds disproportionately affected by disparities in breast cancer.
Narendra Wajapeyee, PhD is the recipient of a Sidney Kimmel Scholar Award to support his project, Deciphering and Targeting RAS-mutant Cancers. Dr. Wajapeyee is an Assistant Professor of Pathology and a member of the Yale Cancer Center Signal Transduction Research Program.
April 29, 2011
William C. Sessa, PhD, a member of the Yale Cancer Center Developmental Therapeutics Program, has been named the Alfred Gilman Professor of Pharmacology. Dr. Sessa is an expert on blood vessel function and also Vice Chair of the department of pharmacology at Yale School of Medicine.
Qin Yan, PhD and Tae Hoon Kim, PhD, members of the Cancer Genetics and Genomics Program, have been selected as the 2011 Stewart Fellowships from Yale Cancer Center. The award is for $75,000 for each of the next two years.
April 15, 2011
Tracy Carafeno, RN, MS has been chosen by the American Organization of Nurse Executives (AONE) as a nurse leader fellow for 2011.
April 1, 2011
Melinda Irwin has been awarded a $1 million grant from the Society for Women's Health Research in partnership with the Susan G. Komen Foundation to study the link between exercise and breast cancer. The grant is shared with Dr. Jennifer Ligibel at Dana-Farber Cancer Institute and Dr. Deborah Dillon at Brigham and Women's Hospital.
Abhijit Patel has been awarded the Yale School of Public Health Ovarian Cancer Early Detection and Prevention Research Award. The award of $105,000 will support his research into next generation sequencing for early detection of ovarian tumor DNA in blood.
Qin Yan was recently awarded a $100,000 grant from the Melanoma Research Foundation to study the Roles of Epigenetic Regulator JARID1B in Metastatic Melanoma.
March 18, 2011
Lynn Wilson has been named a trustee of the American Board of Radiology (ABR). His four-year term of service will begin July 1, 2011. ABR trustees participate in leadership and decision making to carry out the ABR's mission and set standards for the board certification process in radiology for initial certification and maintenance of certification. Dr. Wilson is certified by the ABR in radiation oncology.
Dr. Roy S. Herbst was featured in the Winter/Spring issue of Centerpoint Newsletter.