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Pediatric Cancers

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A Phase II Trial of Response-Based Radiation Therapy for Pediatric Patients with Localized Central Nervous System Germ Cell Tumors (CNS GCT)
Disease/Condition: Brain and Nervous System
Principal Investigator: Nina Kadan-Lottick
A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib for patients with High Allelic Ratio FLT3/ITD
Disease/Condition: Cancer | Myeloid and Monocytic Leukemia
Principal Investigator: Nina Kadan-Lottick
A Phase III Study of Risk Directed Therapy for Infants with Acute Lymnphoblastic Leukemia (ALL): Randomization of Highest Risk Infants to Intensive Chemotherapy +-FLT3 Inhibition
Disease/Condition: Leukemia, other
Principal Investigator: Nina Kadan-Lottick
A Randomized Phase III Study of Standard Cytarabine Plus Daunomycin (7+3) Therapy versus Idarubicin with High Dose Cytarabine (IA) with or without Vorinostat (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML)
Disease/Condition: Myeloid and Monocytic Leukemia
Principal Investigator: Nikolai Podoltsev
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Disease/Condition: Adult Rhabdomyosarcoma | Childhood Desmoplastic Small Round Cell Tumor | Chordoma | Desmoid Tumor | Metastatic Childhood Soft Tissue Sarcoma | Nonmetastatic Childhood Soft Tissue Sarcoma | Previously Treated Childhood Rhabdomyosarcoma | Previously Untreated Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Soft Tissue | Stage I Adult Soft Tissue Sarcoma | Stage II Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma
Principal Investigator: Nina Kadan-Lottick
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Disease/Condition: Adult Supratentorial Primitive Neuroectodermal Tumor (PNET) | Childhood Supratentorial Primitive Neuroectodermal Tumor | Ewing Sarcoma of Bone | Extraosseous Ewing Sarcoma | Extraosseous Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor | Peripheral Primitive Neuroectodermal Tumor of the Kidney | Soft Tissue | Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor
Principal Investigator: Gary Kupfer
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer
Disease/Condition: Childhood Hepatoblastoma | Liver | Stage I Childhood Liver Cancer | Stage II Childhood Liver Cancer | Stage III Childhood Liver Cancer | Stage IV Childhood Liver Cancer
Principal Investigator: Nina Kadan-Lottick
Intergroup Trial for Children or Adolescents With B-Cell Non Hodgkin Lymphoma or B-Acute Leukemia: Evaluation of Rituximab Efficacy and Safety in High Risk Patients - Phase III Trial
Disease/Condition: Leukemia, other
Principal Investigator: Nina Kadan-Lottick
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
Disease/Condition: Brain and Nervous System | Childhood Infratentorial Ependymoma | Childhood Supratentorial Ependymoma | Newly Diagnosed Childhood Ependymoma
Principal Investigator: Nina Kadan-Lottick
Neuroblastoma Antibody Study
Disease/Condition: Brain and Nervous System | Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma
Principal Investigator: Nina Kadan-Lottick
Newly Diagnosed High Risk B-Precursor ALL - Clofarabine
Disease/Condition: Leukemia, not otherwise specified
Principal Investigator: Nina Kadan-Lottick
Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia
Disease/Condition: B-cell Childhood Acute Lymphoblastic Leukemia | Leukemia | Lymphoid Leukemia | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia | Untreated Adult Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia
Principal Investigator: Nina Kadan-Lottick
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Disease/Condition: Untreated Adult Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia
Principal Investigator: Nina Kadan-Lottick
Study of Kidney Tumors in Young Patients
Disease/Condition: Clear Cell Sarcoma of the Kidney | Congenital Mesoblastic Nephroma | Diffuse Hyperplastic Perilobar Nephroblastomatosis | Rhabdoid Tumor of the Kidney | Stage I Renal Cell Cancer | Stage I Wilms Tumor | Stage II Renal Cell Cancer | Stage II Wilms Tumor | Stage III Renal Cell Cancer | Stage III Wilms Tumor | Stage IV Renal Cell Cancer | Stage IV Wilms Tumor | Stage V Wilms Tumor
Principal Investigator: Gary Kupfer
Study of Late-Occurring Complications in Childhood Cancer Survivors
Disease/Condition: Cancer Survivor | Cardiovascular Complications | Hematopoietic/Lymphoid Cancer | Unspecified Childhood Solid Tumor, Protocol Specific
Principal Investigator: Kupfer, Gary