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Colorectal Cancer

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Studies of in-vivo 5-fluorouracil pharmacokinetics, with and without bevacizumab in patients with liver metastases from adenocarcinoma of the colon
Disease/Condition: Colon Cancer
Principal Investigator: Howard S Hochster
A Phase 1, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of Ascending Doses of AZD4547 in Patients with Advanced Solid Tumor Malignancies
Disease/Condition: Advanced Solid Cancers
Principal Investigator: Howard S Hochster
Phase I/IIa First Time in Human study of GSK2636771 in subjects with advanced solid tumors
Disease/Condition: Breast Cancer (ER, PR, and HER2 negative) | Colorectal Cancer | Endometrial Cancer | Gastric Adenocarcinoma | Glioblastoma Multiforme | Head/ Neck Squamous Cell Carcinoma | Melanoma | Non-Small Cell Lung Cancer (NSCLC) | Ovarian Cancer | Prostate Cancer
Principal Investigator: Roy Herbst
A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients using ColoPrint
Disease/Condition: Colon Cancer
Principal Investigator: Vikram Reddy
Phase II-III study to Evaluate the Efficacy and Safety of T-DM1 versus. Taxane in HER-2 positive Gastric Cancer and Gastroesophageal Cancer
Disease/Condition: Adenocarcinoma of the Gastroesophageal Junction | Gastric Cancer
Principal Investigator: Howard S Hochster
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients with Advanced Breast and Gastrointestinal Tumors
Disease/Condition: Gastrointestinal Tumors | Metastatic Breast Cancer
Principal Investigator: Gina G Chung
Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer
Disease/Condition: Adenocarcinoma of the Esophagus | Adenocarcinoma of the Gastroesophageal Junction | Stage IB Esophageal Cancer | Stage IIA Esophageal Cancer | Stage IIB Esophageal Cancer | Stage IIIA Esophageal Cancer | Stage IIIB Esophageal Cancer
Principal Investigator: Bryan William Chang
Phase III Study of TAS-102 plus Best Supportive Care versus Placebo plus Best Supportive Care in Patients with Colorectal Cancer
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Randomized, double-blind, Phase II Study of FOLFOX/Bevacizumab with MetMAb versus Placebo as First-Line Treatment for Patients with Metastatic Colorectal Cancer
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster