Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
What is the purpose of this trial?
This randomized phase III trial studies combination chemotherapy to see how well it works compared to combination chemotherapy with topotecan hydrochloride in treating patients with non-metastatic extracranial Ewing sarcoma. Drugs used in chemotherapy, such as vincristine sulfate, doxorubicin hydrochloride, cyclophosphamide, ifosfamide, etoposide, and topotecan hydrochloride, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. It is not yet known whether combination chemotherapy is more effective with topotecan hydrochloride in treating Ewing sarcoma.
- N/A - 50 Years
- Children's Oncology Group
National Cancer Institute (NCI)
- November 2010
- Last Updated:
- August 6, 2014
- Study HIC#:
Clinicaltrials.gov ID: NCT01231906