Clinical Trials
Pediatric Cancers
10
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| A Phase II Study of Cixutumumab (IMC-A12; IND# 100947) in Combination with Temsirolimus (IND# 61010) in Pediatric Patients with Recurrent or Refractory Solid Tumors (ADVL1221) Disease/Condition: Recurrent or Refractory Solid Tumors Principal Investigator: Nina Kadan-Lottick |
| Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Disease/Condition: Neuroblastoma Principal Investigator: Kupfer, Gary |
| Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Disease/Condition: Leukemia | Lymphoma Principal Investigator: Gary Kupfer |
| Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia Disease/Condition: Cognitive/Functional Effects | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment Principal Investigator: Gary Kupfer |
| Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy Disease/Condition: Fungal Infection | Leukemia | Neutropenia Principal Investigator: Nina Kadan-Lottick |
| Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor Disease/Condition: Brain and Central Nervous System Tumors Principal Investigator: Gary Kupfer |
| Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Disease/Condition: Chordoma | Desmoid Tumor | Sarcoma Principal Investigator: Gary Kupfer |
| Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Disease/Condition: Rhabdomyosarcoma Principal Investigator: Gary Kupfer |
| Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Disease/Condition: Brain and Central Nervous System Tumors | Kidney Cancer | Sarcoma Principal Investigator: Gary Kupfer |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer Disease/Condition: Liver Cancer Principal Investigator: Nina Kadan-Lottick |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Disease/Condition: Contiguous Stage II Adult Lymphoblastic Lymphoma | Noncontiguous Stage II Adult Lymphoblastic Lymphoma | Stage II Adult T-cell Leukemia/Lymphoma | Stage II Childhood Lymphoblastic Lymphoma | Stage III Adult Lymphoblastic Lymphoma | Stage III Adult T-cell Leukemia/Lymphoma | Stage III Childhood Lymphoblastic Lymphoma | Stage IV Adult Lymphoblastic Lymphoma | Stage IV Adult T-cell Leukemia/Lymphoma | Stage IV Childhood Lymphoblastic Lymphoma | T-cell Adult Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia | Untreated Adult Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia Principal Investigator: Gary Kupfer |
| Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Disease/Condition: Brain and Central Nervous System Tumors Principal Investigator: Gary Kupfer |
| Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma Disease/Condition: Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma Principal Investigator: Nina Kadan-Lottick |
| Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Disease/Condition: Brain and Central Nervous System Tumors | Chronic Myeloproliferative Disorders | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Lymphoma | Lymphoproliferative Disorder | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic Syndromes | Myelodysplastic/Myeloproliferative Neoplasms | Precancerous Condition | Unspecified Childhood Solid Tumor, Protocol Specific Principal Investigator: Gary Kupfer |
| Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Disease/Condition: Leukemia Principal Investigator: Kupfer, Gary |
| Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma Disease/Condition: Brain and Central Nervous System Tumors Principal Investigator: Gary Kupfer |
| Neuropsychological and Behavioral Testing in Young Patients With Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET) Disease/Condition: Brain and Central Nervous System Tumors | Chemotherapeutic Agent Toxicity | Cognitive/Functional Effects | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment | Radiation Toxicity | Therapy-related Toxicity Principal Investigator: Gary Kupfer |
| Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia Disease/Condition: Leukemia Principal Investigator: Gary Kupfer |
| Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Disease/Condition: Leukemia Principal Investigator: Nina Kadan-Lottick |
| Study of Blood Samples From Newborns With Down Syndrome Disease/Condition: Down Syndrome | Leukemia Principal Investigator: Nina Kadan-Lottick |
| Study of Kidney Tumors in Young Patients Disease/Condition: Kidney Cancer | Nonneoplastic Condition Principal Investigator: Gary Kupfer |
| Study of Late-Occurring Complications in Childhood Cancer Survivors Disease/Condition: Cancer Principal Investigator: Kupfer, Gary |
| Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Metastatic Childhood Soft Tissue Sarcoma | Previously Untreated Childhood Rhabdomyosarcoma | Stage IV Adult Soft Tissue Sarcoma Principal Investigator: Nina Kadan-Lottick |
| Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms Tumor Disease/Condition: Kidney Cancer Principal Investigator: Kupfer, Gary |
| Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Mixed Childhood Rhabdomyosarcoma | Pleomorphic Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Childhood Rhabdomyosarcoma Principal Investigator: Nina Kadan-Lottick |
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