Roy S Herbst, MD, PhD

Ensign Professor of Medicine (Medical Oncology) and Professor of Pharmacology; Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital ; Associate Director for Translational Research, Yale Cancer Center; Disease Aligned Research Team (DART) Leader, Thoracic Oncology Program, Yale Cancer Center

Departments & Organizations

Medical Oncology: Subset Medical Oncology Faculty

Faculty Research

Secondary Faculty

Yale Cancer Center: Developmental Therapeutics | SPORE in Lung Cancer | Thoracic Oncology Program | Yale CTAP

Yale Medicine

Office of Cooperative Research


Dr. Herbst is nationally recognized for his leadership and expertise in lung cancer treatment and research. He is best known for his work in developmental therapeutics and the personalized therapy of non-small cell lung cancer, in particular the process of linking genetic abnormalities of cancer cells to novel therapies.

He is a member of the American Association for Cancer Research (AACR), where he chairs the Tobacco Task Force, as well as the American Society of Clinical Oncology and the Institute of Medicine’s National Cancer Policy Forum. He is a fellow of the American College of Physicians. Dr. Herbst is also a vice chair of the Southwest Oncology Group’s lung committee, a member of the medical advisory committee for the Lung Cancer Research Foundation and chair of the communications committee for the International Association for the Study of Lung Cancer. He has authored more than 200 peer-reviewed papers and has current grant funding for his work from numerous sources including the National Cancer Institute, AACR and multiple charitable foundations.

Dr. Herbst received his medical degree from Cornell University Medical College and earned a Ph.D. in molecular cell biology from the Rockefeller University. He completed his medical oncology fellowship at Dana Farber Cancer Institute and a medical hematology fellowship at Brigham and Women’s Hospital in Boston, where he additionally received a master’s degree from Harvard University in their clinical investigator training program.

Education & Training

MMS Harvard University, Clinical Translational Research (1997)
MD Cornell University Medical College (1991)
PhD Rockefeller University (1990)
BS Yale University, Molecular Biophysics & Biochemistry (1984)
MS Yale University, Molecular Biophysics and Biochemistry (1984)
Fellowship Brigham and Women`s Hospital
Fellowship Dana Farber Cancer Institute
Residency Brigham and Women`s Hospital
Board Certification AB of Internal Medicine, Medical Oncology (1997, recertified: 2007)

Honors & Recognition

  • Elected to the Association of American PhysiciansAAP (2015)

  • Addario Foundation Lectureship AwardBonnie Addario Foundation (2014)

  • Alvin S. Slotnick Lecture Award for notable contributions to lung cancer researchDana-Farber/Brigham and Women’s Cancer Center (2014)

  • Best Doctors, New York Magazine (2014)

  • Honorary Professor, University College London Cancer CenterUniversity College London (2012)

  • Sikand OratorYale University (2011)

Professional Service

  • National Cancer Institute (2012) Thoracic Malignancy Steering Committee - National Cancer Institute

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Contact Info

Roy S Herbst, MD, PhD
Patient Care Location
Yale Cancer CenterYale-New Haven Hospital
20 York Street, Ste North Pavilion 4

New Haven, CT 06510
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Mailing Address
PO Box 208028
New Haven, CT 06520-8028

Curriculum Vitae