Meena Savur Moran, MD

Professor of Therapeutic Radiology and Assistant Clinical Professor of Nursing; Medical Director for Radiation Oncology at the Lawrence and Memorial Cancer Center; Director, Yale Breast Radiotherapy Program

Departments & Organizations

Therapeutic Radiology: Breast Cancer Radiotherapy

Cancer Center: Breast Center | Radiobiology & Radiotherapy

Faculty Research

Radiobiology and Radiotherapy

Yale Medicine

Office of Cooperative Research

Biography

Overview: The primary focus of my clinical research has been on clinical, pathological and molecular factors which may predict for outcomes in breast cancer patients treated with radiation therapy, ethnic variations in breast cancer, quality improvement, guidelines, and standards in breast health care delivery, and investigating radiation techniques. I am the medical director of Radiation Therapy at YNHH's Lawrence and Memorial Hospital in Waterford. I I have been on the board of directors of the National Accreditation Program for Breast Centers (NAPBC) of the American College of Surgeons for the last 5 years and have worked to develop national guidelines, standards and a surveying process for accreditation of breast centers, was on the editorial board for the Journal of Clinical Oncology and The Breast Journal for 3 years each, Associate Senior Breast Editor for International Journal of Radiation Therapy, Biology, Physics for 5 years, a member of the American College of Radiology Breast Appropriateness Criteria Committee to established clinical guidelines for breast cancer treatment, the NCCN Breast Panel and the American Board of Radiology Breast Panel for written and oral boards. Lastly, I have co-chaired the margins guidelines for breast conservation therapy (Society for Surgical Oncology SSO/ American Society of Clinical Oncology ASTRO).

Selected Breast-Related Publications:

Morrow M, Van Zee KJ, Solin LJ, Houssami N, Chavez-MacGregor M, Harris JR, Horton J, Hwang S, Johnson PL, Marinovich ML, Schnitt SJ, Wapnir I, Moran MS. Society of Surgical Oncology-American Society for Radiation Oncology-American Society of Clinical Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Ductal Carcinoma In Situ.J Clin Oncol. 2016 Aug 15 PMID: 27528719


Moran MS, Schnitt SJ, Giuliano AE, Harris JR, Khan SA, Horton J, Klimberg S, Chavez-MacGregor M, Freedman G, Houssami N, Johnson PL, Morrow MSociety of Surgical Oncology-American Society for Radiation Oncology consensus guideline on margins for breast-conserving surgery with whole-breast irradiation in stages I and II invasive breast cancer J Clin Oncol. 2014 May 10;32(14):1507-15.PMID: 24516019


Gradishar WJ, Anderson BO, Balassanian R, Blair SL, Burstein HJ, Cyr A, Elias AD, Farrar WB, Forero A, Giordano SH, Goetz M, Goldstein LJ, Hudis CA, Isakoff SJ, Marcom PK, Mayer IA, McCormick B, Moran M, Patel SA, Pierce LJ, Reed EC, Salerno KE, Schwartzberg LS, Smith KL, Smith ML, Soliman H, Somlo G, Telli M, Ward JH, Shead DA, Kumar R.Invasive Breast Cancer Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw. 2016 Mar;14(3):324-54. PMID: 26957618


Ding X, Yang Q, Kong X, Haffty BG, Gao S, Moran MS. Radiosensitization effect of Huaier on breast cancer cells. Oncol Rep. 2016 May;35(5):2843-50. PMID: 26935024


DeSnyder SM, Hunt KK, Smith BD, Moran MS, Klimberg S, Lucci A.Assessment of Practice Patterns Following Publication of the SSO-ASTRO Consensus Guideline on Margins for Breast-Conserving Therapy in Stage I and II Invasive Breast Cancer.Ann Surg Oncol. 2015 Oct;22(10):3250-6. PMID: 26202554


Schnitt SJ, Moran MS, Houssami N, Morrow M.The Society of Surgical Oncology-American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer: Perspectives for Pathologists.Arch Pathol Lab Med. 2015 May;139(5):575-7. PMID: 25153620


Zhang X, Li X, Zhang N, Yang Q, Moran MS. Low dose ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithilial-mesenchymal transition. Biochem Biophys Res Commun. Aug 2011;412(1):188-92. PMID: 25893590


Moran MS.Radiation therapy in the locoregional treatment of triple-negative breast cancer. Lancet Oncol. 2015 Mar;16(3):e113-22. Review. PMID: 25752562


Moran MS, Gonsalvas L, Goss D, Ma S..Breast Cancers in US Residing Indian-Pakistani versus Non-Hispanic White Women: Comparative Analysis of Clinical-Pathologic Features, Treatment and Survival. Br Can Res Treat July 2011;128:(2):543-51


Schnitt SJ, Moran MS, Houssami N, Morrow M.The Society of Surgical Oncology-American Society for Radiation Oncology Consensus Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stages I and II Invasive Breast Cancer: Perspectives for Pathologists.Arch Pathol Lab Med. 2015 May;139(5):575-7. PMID: 25153620


Truong PT, Smith SL, Moran MS.Perspectives in breast cancer treatment: APBI and breast-conserving surgery. Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):967-8. PMID: 25585789


Moran MS, Truong PT. Intraoperative accelerated partial breast irradiation: caution still warranted. Int J Radiat Oncol Biol Phys. 2014 Jul 1;89(3):496-8. PMID: 24929161


Moran MS.Should low-risk patients be treated with three-dimensional conformal radiation therapy-accelerated partial-breast irradiation in an off-protocol setting? J Clin Oncol. 2013 Nov 10;31(32):4032-7. PMID:24081936


Moran MS, Goss D, Haffty BG, Kaufman CS, Winchester DP. Editorial: Quality Measures, Standards, and Accreditation for Breast Centers in the United States. Int J Rad Onc Biol Phy 2010 Jan 1; 76(1):1-4.


Hafeez F, Neboori HJ, Harigopal M, Wu H, Haffty BG, Yang Q, Schiff D, Moran MS. Is Ki-67 expression prognostic for local relapse in early-stage breast cancer patients treated with breast conservation therapy (BCT)? Int J Radiat Oncol Biol Phys. 2013 Oct 1;87(2):344-8.PMID: 23910708


Moran MS, Kaufman C, Burgin C, Swain S, Granville T, Winchester DP.What currently defines a breast center? Initial data from the national accreditation program for breast centers.J Oncol Pract. 2013 Mar;9(2):e62-70. PMID: 23814526


Khan AJ, Parikh RR, Neboori HJ, Goyal S, Haffty BG, Moran MS.The relative benefits of tamoxifen in older women with T1 early-stage breast cancer treated with breast-conserving surgery and radiation therapy.Breast J. 2013 Sep-Oct;19(5):490-5. PMID: 23800027


Bai HX, Motwani SB, Higgins SA, Haffty BG, Wilson LD, Lannin DR, Evans SB, Moran MS. Breast conservation therapy for ductal carcinoma in situ (DCIS): does presentation of disease affect long-term outcomes?Int J Clin Oncol. 2014;19(3):460-6. PMID: 23780727


Jones T, Neboori H, Wu H, Yang Q, Haffty BG, Evans S, Higgins S, Moran MS.Are breast cancer subtypes prognostic for nodal involvement and associated with clinicopathologic features at presentation in early-stage breast cancer? Ann Surg Oncol. 2013 Sep;20(9):2866-72. PMID: 23661183


Moran MS.Should triple-negative breast cancer (TNBC) subtype affect local-regional therapy decision making?Am Soc Clin Oncol Educ Book. 2014:e32-6.PMID: 248571204.


Halyard MY, Harris EE, Bailey L, Bellon JR, Freedman GM, Goyal S, Horst KC, Moran MS, Park CC, Suh WW, Toppmeyer D, Haffty BG.ACR Appropriateness Criteria local-regional recurrence (LRR) and salvage surgery-breast cancer.Oncology (Williston Park). 2014 Feb;28(2):157-64, C3.PMID: 24701707


Evans SB, Panigrahi B, Northrup V, Patterson J, Baldwin DE, Higgins SA, Moran MS. Analysis of coronary artery dosimetry in the 3-dimensional era: Implications for organ-at-risk segmentation and dose tolerances in left-sided tangential breast radiation.Pract Radiat Oncol. 2013 Apr-Jun;3(2):e55-60. PMID: 24674321


Nelson C, Bai H, Neboori H, Takita C, Motwani S, Wright JL, Hobeika G, Haffty BG, Jones T, Goyal S, Moran MS.Multi-institutional experience of ductal carcinoma in situ in black vs white patients treated with breast-conserving surgery and whole breast radiation therapy. Int J Radiat Oncol Biol Phys. 2012 Nov 1;84(3):e279-83. PMID: 22672752


Moran MS, Ma S, Jagsi R, Yang TJ, Higgins SA, Weidhaas JB, Wilson LD, Lloyd S, Peschel R, Gaudreau B, Rockwell S.A prospective, multicenter study of complementary/alternative medicine (CAM) utilization during definitive radiation for breast cancer.Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):40-6. PMID: 22658441


Moran MS, Bai HX, Harris EE, Arthur DW, Bailey L, Bellon JR, Carey L, Goyal S, Halyard MY, Horst KC, MacDonald SM, Haffty BG;ACR appropriateness criteria(®) ductal carcinoma in situ.American College of Radiology Breast Expert Panel.Breast J. 2012 Jan-Feb;18(1):8-15. PMID: 22107336


Castrucci W, Lannin D, Haffty BG, Higgins SA, Moran MS. Using nodal ratios to predict risk of regional recurrences in patients treated with breast conservation therapy with 4 or more positive lymph nodes.SRN Surg. 2011;2011. PMID: 22084784


Moran MS, Knobf MT. Raising the bar for breast health care in the United States.Womens Health Issues. 2012 Mar;22(2):e129-33.PMID: 22037415


Macdonald SM, Harris EE, Arthur DW, Bailey L, Bellon JR, Carey L, Goyal S, Halyard MY, Horst KC, Moran MS, Haffty BG. ACR appropriateness criteria® locally advanced breast cancer.Breast J. 2011 Nov-Dec;17(6):579-85. PMID: 21906206


Zhang X, Li X, Zhang N, Yang Q, Moran MS. Low doses ionizing radiation enhances the invasiveness of breast cancer cells by inducing epithelial-mesenchymal transition. Biochem Biophys Res Commun. 2011 Aug 19;412(1):188-92. PMID: 21810413


Bellon JR, Harris EE, Arthur DW, Bailey L, Carey L, Goyal S, Halyard MY, Horst KC, Moran MS, MacDonald SM, Haffty BG; ACR Appropriateness Criteria® conservative surgery and radiation--stage I and II breast carcinoma: expert panel on radiation oncology: breast.American College of Radiology..Breast J. 2011 Sep-Oct;17(5):448-55. PMID: 21790842


Moran MS, Gonsalves L, Goss DM, Ma S.Breast cancers in U.S. residing Indian-Pakistani versus non-Hispanic White women: comparative analysis of clinical-pathologic features, treatment, and survival. Breast Cancer Res Treat. 2011 Jul;128(2):543-51. PMID: 21301957


Moran MS, Yang Q, Goyal S, Harris L, Chung G, Haffty BG.Evaluation of vascular endothelial growth factor as a prognostic marker for local relapse in early-stage breast cancer patients treated with breast-conserving therapy.Int J Radiat Oncol Biol Phys. 2011 Dec 1;81(5):1236-43.PMID: 21093162


Parikh RR, Haffty BG, Lannin D, Moran MS. Ductal carcinoma in situ with microinvasion: prognostic implications, long-term outcomes, and role of axillary evaluation.Int J Radiat Oncol Biol Phys. 2012 Jan 1;82(1):7-13.PMID: 20950955


Yang TJ, Haffty BG, Yang Q, Moran MS. Prognostic Implications of Mammographically Occult, Early Stage Breast Cancer Patients Treated with Breast Conservation Therapy. Int J Radiat Onc Biol Phys 2010 Jan 1;76(1):79-84


Sharma C, Harris L, Yang Q, Haffty BG, Moran MS. Does Compliance with Radiation Therapy Differ in African American Patients with Early Stage Breast Cancer? Breast J. 2009 Dec 16.


Ma S, Huang J, Moran MS. Identification of genes associated with multiple cancers via integrative analysis. BMC Genomics, 2009 Nov 17;10: 535-539


Moran MS, Yang Q, Haffty, BG. The Yale University Experience of Early-Stage Invasive Lobular Carcinoma (ILC) and Invasive Ductal Carcinoma (IDC) Treated with Breast Conservation Treatment (BCT): Analysis of Clinical-Pathologic Features, Long Term Outcomes, and Molecular Expression of COX-2, Bcl-2 and p53 as a Function of Histology. Breast Journal 2009 Nov/Dec;15(6): 571-8.


Moran MS, Haffty BG. Radiation Techniques and Toxicities for Locally Advanced Breast Cancer. Semin Rad Onc 2009 Oct;19(4):244-55


Haffty BG, Choi DH, Goyal S, Silber A, Ranieri K, Matloff E, Hyuk M, Nisselblatt M, Toppermeyer D, Moran MS. Breast Cancer in Young Women: Prevalence of BRCA 1 and 2 Mutations and Risk of Secondary Malignancies across Diverse Racial Groups. Ann Oncol. 2009 June 2


Goyal S, Parikh RR, Green C, Schiff D, Moran MS, Yang Q, Haffty BG. Clinicopathologic significance of excision repair cross-complementation 1 (ERCC-1) expression in patients treated with breast conserving surgery and radiation therapy. Int J Radiat Onc Biol Phys 2009, May 21


Lui GF, Yang Q, Haffty BG, Moran MS. Clinical-pathologic Features and Outcomes of Tubular Carcinoma of the Breast Compared with Invasive Ductal Carcinoma Treated with Breast Conservation Therapy. Int J Radiat Onc Biol Phys 2009 Dec 1;75(5):1304-8


Yang Q, Moran MS, Haffty BG. Bcl-2 Expression Predicts Local Relapse for Early-Stage Breast Cancer Receiving Conserving Surgery and Radiotherapy. Breast Canc Res Treat 2009 May; 115(2):343-8


Moran MS, Yang, Q, Harris LN, Jones B, Tucker D, Haffty BG. Long Term Outcomes and Clinical-Pathologic Differences between African American and Caucasian Patients Treated with Breast Conservation Therapy for Early Stage Breast Cancer. Cancer. Nov 1 2008;113(9):2565-2574.

Education & Training

MD Cornell University Medical College (1994)
Resident Yale-New Haven Hospital
Intern Roosevelt Hospital, Columbia University
Board Certification AB of Radiology, Radiation Oncology (1999)

Professional Service

  • Breast Expert Panel-Radiation Oncology, Appropriateness Criteria Committee American College of Radiology (2009)

  • Chair, American Society of Therapeutic Radiation Oncology, Breast Abstract Panel/Scientific Sub-Committee (2009 - 2012)

  • 3rd Annual American Society of Clinical Oncology Breast Symposium, Member (2009)

  • Information Technology Committee Member (2008 - 2012)

  • Member, Information Technology and Outcome/ National Breast Cancer Database Committee (2008 - 2012)

  • Member, Breast Abstract Review Committee, 50th Annual American Society of Therapeutic Radiology and Oncology, (2008 - 2012)

  • Chair, American Radium Society Nomination Committee, 2008-2011 (2008 - 2011)

  • Moderator, faculty, discussant, committees American Radium Society (ARS) (2008 - 2010)

  • Chair, ASCO Breast Symposium, Radiation Therapy Section III (2008 - 2008)

  • Member, Program Committee, 2nd Annual American Society of Clinical Oncology Breast Symposium, (2008)

  • Oral Board Examiner, Breast, American Board of Radiology (2007 - 2009)

  • Member, Abstract Review Committee, 2nd & 3rd Annual American Society of Clinical Oncology Breast Symposium, (2007 - 2009)

  • Article reviewer, guest editor, presenter at national meeting, commentaries/editorial for society’s journal, Breast Disease: A Year Book Quarterly American Society of Breast Diseases (ASBD) (2007 - 2009)

  • Elected board member, National Accreditation Program for Breast Centers (NAPBC) board (2006 - 2012)

  • Moderator, presenter, discussant, committee member American Society of Therapeutic Radiology & Oncology (ASTRO) (2006 - 2012)

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Contact Info

Meena Savur Moran, MD
Patient Care Location
Yale Therapeutic RadiologyLawrence + Memorial Cancer Center
230 Waterford Parkway South

Waterford, CT 06385
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Office Location
Yale Therapeutic RadiologySmilow Cancer Hospital at Yale - New Haven
35 Park Street, Ste LL 516

New Haven, CT 06511
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Mailing Address
P. O. Box 208040
New Haven, CT 06520-8040

Curriculum Vitae