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Malini Harigopal MD

Associate Professor of Pathology

Research Interests

Cancer biomarkers; Breast; Thyroid; Immunohistochemistry; AQUA method of analysis in tissue microarrays and cytologic material


Research Summary

Biomarker studies in breast cancer and pancreatic cancers using an objective and quantitative method of analysis (AQUA) in tissue microarrays.

Extensive Research Description

Biomarker studies in breast cancer and pancreatic cancers using an objective and quantitative method of analysis (AQUA) in tissue microarrays.


Selected Publications

  • Moeder CB, Giltnane JM, Harigopal M etal: Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome. J Clin Oncol. 2007 Dec 125(34):5418-25.
  • Rimm DL, Giltnane JM, Harigopal M et al: Bimodal population or pathologist artifact? J Clin Oncol. 2007 Jun 1025(17):2487-8.
  • Sherman ME, Rimm DL, Yang XR et al:Variation in breast cancer hormone receptor and HER2 levels by etiologic factors: a population-based analysis. Int J Cancer. 2007 Sep 1121(5):1079-85.
  • Dolled Filhart M, Ryeden L, Cregger M et al: Classification of breast cancer using genetic algorithms and tissue microarrays. Clin Cancer Res. 2006 Nov 112(21):6459-68
  • Harigopal M, Shin SJ, Murray MP et al: Aberrant E-cadherin staining patterns in invasive mammary carcinoma. World J Surg Oncol. 2005 Nov 143:73.
  • Harigopal M, Berger AJ, Camp DL et al: Automated quantitative analysis of E-cadherin expression in lymph node metastases is predictive of survival in invasive ductal breast cancer. Clin Cancer Res. 2005 Jun 111(11):4083-9
  • Harigopal M, Murray MP, Rosen P et al: Prepubertal gynecomastia with lobular differentiation. Breast J. 2005 Jan-Feb11(1):48-51. Review.

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