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Jaime Grutzendler MD

Associate Professor of Neurology and of Neurobiology; Director, Yale Center for Experimental Neuroimaging (YCEN)

Departments & Organizations

Affiliated Faculty

Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Medicine, Pharmacology, and Physiology

Interdepartmental Neuroscience Program

Cancer Center, Yale: Signal Transduction

Vascular Biology and Therapeutics Program

Neurobiology

Neurology: Grutzendler Lab


Research Interests

Two-photon microscopy; Neurodegeneration; Alzheimer's; Blood-brain barrier; Microvasculature; Synapses; Neuroinflammation; Microglia; Astrocyte; Endothelium, myelin imaging more...


Education

  • M.D., Universidad Javeriana School of Medicine, 1991

Selected Publications

  • Embolus extravasation is an alternative mechanism for cerebral microvascular recanalization. Lam CK, Yoo T, Hiner B, Liu Z, Grutzendler J. Nature. 2010 May 27;465(7297):478-82.
  • CX3CR1 in microglia regulates brain amyloid deposition through selective protofibrillar amyloid-ß phagocytosis. Liu Z, Condello C, Schain A, Harb R, Grutzendler J. J Neurosci. 2010 Dec 15;30(50):17091-101.
  • Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition. C. Condello, A. Schain, J. Grutzendler. Scientific Reports. 2011. 1,19. doi:10.1038/srep00019.

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