Ruslan M. Medzhitov, PhD Elected to the National Academy of Sciences
Earlier this week, Ruslan was announced as the newest member of the National Academy of Sciences from Yale University. Ruslan's research on innate immunity has made groundbreaking progress in the exploration of the relationship between innate and adaptive immunity. He joins 11 other members of Yale Cancer Center who are distinguished members of the National Academy of Sciences.
I am pleased to announce that Erin will join Yale Cancer Center and Smilow Cancer Hospital on August 1st as Assistant Professor of Medical Oncology. Erin joins us from Beth Israel Deaconess Medical Center and will care for patients in the breast cancer program. Her research and clinical focus is on high-risk genetic causes of cancer.
Membership Retreat on May 10th
Please join us for Yale Cancer Center's annual membership retreat on Monday, May 10th at the West Campus. The Annual Retreat is the single most important Cancer Center event each year, serving as a venue for members to forge collaborative relationships. Thus for several reasons, your attendance is key to a successful Retreat and Cancer Center; as an opportunity to establish and strengthen relationships with new and long-standing Center members; to learn of new and on-going research conducted by Center members; and to learn about the Cancer Center and West Campus Core Resources directly from the resource directors. Please RSVP to Paula O'Mara.
Research in the News
Yale Cancer Center Researchers Identify Targets of Natural Immunity to Cancer Stem Cells in Humans
Yale Cancer Center scientists, Dr. Madhav Dhodapkar and Dr. Kavita Dhodapkar, have discovered that OCT4, a protein critical in determining the fate of certain germ-cell tumors, is commonly detected and targeted by the immune system in healthy individuals. Their findings, published in the
Proceedings of the National Academy of Sciences
on April 19, could lead to the development of new vaccines and therapies to target stem cells in several cancers, by boosting this naturally occurring response.
Carbon Nanotubes Boost Cancer-Fighting Cells
Yale University engineers have found that the defects in carbon nanotubes cause T cell antigens to cluster in the blood and stimulate the body's natural immune response. Their findings, which appear as the cover article of the April 20 issue of the journal
, could improve current adoptive immunotherapy, a treatment used to boost the body's ability to fight cancer. The study was led by Tarek Fahmy, PhD, a member of the Developmental Therapeutics Research Program at Yale Cancer Center.
Chromosome's Guardians Susceptible to UV Radiation
The molecular caps at the ends of chromosomes that protect humans against cancer and premature cellular aging show a surprising inability to protect themselves against ultraviolet radiation, a new Yale School of Medicine study led by Douglas Brash, PhD, has found. Brash is a member of the Yale Cancer Center Radiobiology and Radiotherapy Research Program.
Telomeres-the repeat sequences of DNA at the end of chromosomes that act like plastic tips at the end of a shoelace-are much more likely to be damaged by UV radiation than are other common cellular structures, researchers report in the study published online April 29 in the journal
Join us at the Connecticut Challenge
Join the team
"Yale, Smilow and Friends"
for the 6th annual
- a fantastic and fun bike ride to support cancer survivors this summer. All ages and abilities are welcome to ride. Now in its 6th year, the Connecticut Challenge is an annual ride with participants choosing distances of 12, 25, 50, 75 and 100 miles.
The Connecticut Challenge began in partnership with Yale Cancer Center to establish the adult survivorship clinic that bears its name, provide funding to the HEROS clinic for survivors of childhood cancers, and fund pilot grants in survivorship at YCC. In 2009, it expanded its network of sites that offer survivor programming and services across the state, maintaining Yale Cancer Center as its flagship site and founding partner.
This year's ride begins and ends in Fairfield on Saturday, July 24, 2010. Many throughout the Yale community have ridden in past years and we invite you to join us again or for the first time! Bikes are available for rent at the ride. Please read all the ride and fundraising information carefully and if you choose to ride, please join the team "Yale, Smilow and Friends." If you wish to simply support the team with a donation please do so!
Learn More >>
The Yale Center for Analytical Sciences (YCAS) was recently established to bring together existing academic strengths in biostatistics, epidemiology, health economics, and health services research at the Yale School of Public Health and collaborative staff to provide expertise for the design, conduct and analysis of health and health care studies, methodological development and education and training to Yale and the extended research community. Yale Cancer Center members have access to the support of YCAS through a collaborative agreement to create a biostatistical shared resource. In addition, YCAS provides support to the YCC Protocol Review and Quality Assurance, Compliance Safety committees (QUACS).
The Key Functions of the Biostatistics Shared Resource are to:
Assist YCC investigators in the design, conduct and analysis of clinical trials, genomic and proteomic studies as well as population, epidemiologic and prevention studies of cancer.
Provide review and evaluation of statistical design of studies for the Protocol Review Committee and monitoring of studies for QUACS.
Provide statistical collaboration for YCC investigators on grant/protocol preparation - statistical design, power and sample size considerations, and analytic and monitoring plans.
Assist YCC investigators with manuscript preparation and review.
Organize workshops and training to educate YCC investigators on the statistical aspects of study design and analysis of cancer studies.
YCAS research design clinics are held every Wednesday from 12 to 2 PM in Room 108 in the School of Public Health. Clinics are free of charge. To schedule an appointment, please contact YCAS and provide a short description of your research question.