MRS Group Publications

Coman D, Sanganahalli BG, Jiang L, Hyder F, Behar KL: Distribution of temperature changes and neurovascular coupling in rat brain following 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") exposure. NMR Biomed. 2015 Aug 19; 2015 Aug 19. PMID: 26286889

Shulman RG, Rothman DL: Homeostasis and the glycogen shunt explains aerobic ethanol production in yeast. Proc Natl Acad Sci U S A. 2015 Aug 17; 2015 Aug 17. PMID: 26283370

Umesh Rudrapatna S, Juchem C, Nixon TW, de Graaf RA: Dynamic multi-coil tailored excitation for transmit B1 correction at 7 Tesla. Magn Reson Med. 2015 Jul 30; 2015 Jul 30. PMID: 26223503

Patel AB, de Graaf RA, Rothman DL, Behar KL: Effects of γ-Aminobutyric acid transporter 1 inhibition by tiagabine on brain glutamate and γ-Aminobutyric acid metabolism in the anesthetized rat In vivo. J Neurosci Res. 2015 Jul; 2015 Feb 6. PMID: 25663257

Youngblood MW, Chen WC, Mishra AM, Enamandram S, Sanganahalli BG, Motelow JE, Bai HX, Frohlich F, Gribizis A, Lighten A, Hyder F, Blumenfeld H: Rhythmic 3-4Hz discharge is insufficient to produce cortical BOLD fMRI decreases in generalized seizures. Neuroimage. 2015 Apr 1; 2015 Jan 3. PMID: 25562830

Motelow JE, Li W, Zhan Q, Mishra AM, Sachdev RN, Liu G, Gummadavelli A, Zayyad Z, Lee HS, Chu V, Andrews JP, Englot DJ, Herman P, Sanganahalli BG, Hyder F, Blumenfeld H: Decreased subcortical cholinergic arousal in focal seizures. Neuron. 2015 Feb 4. PMID: 25654258

Strohbehn G, Coman D, Han L, Ragheb RR, Fahmy TM, Huttner AJ, Hyder F, Piepmeier JM, Saltzman WM, Zhou J: Imaging the delivery of brain-penetrating PLGA nanoparticles in the brain using magnetic resonance. J Neurooncol. 2015 Feb; 2014 Nov 18. PMID: 25403507

Befroy DE, Kibbey RG, Perry RJ, Petersen KF, Rothman DL, Shulman GI: Response to burgess. Nat Med. 2015 Feb. PMID: 25654597

Romei C, Di Fulvio A, Traino CA, Ciolini R, d'Errico F: Characterization of a low-cost PIN photodiode for dosimetry in diagnostic radiology. Phys Med. 2015 Feb; 2014 Nov 20. PMID: 25465072

Juchem C, Umesh Rudrapatna S, Nixon TW, de Graaf RA: Dynamic multi-coil technique (DYNAMITE) shimming for echo-planar imaging of the human brain at 7 Tesla. Neuroimage. 2015 Jan 15; 2014 Nov 8. PMID: 25462795

Huang Y, Coman D, Ali MM, Hyder F: Lanthanide ion (III) complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraaminophosphonate for dual biosensing of pH with chemical exchange saturation transfer (CEST) and biosensor imaging of redundant deviation in shifts (BIRDS). Contrast Media Mol Imaging. 2015 Jan-Feb; 2014 May 6. PMID: 24801742

Hertz L, Rothman DL, Li B, Peng L: Chronic SSRI stimulation of astrocytic 5-HT2B receptors change multiple gene expressions/editings and metabolism of glutamate, glucose and glycogen: a potential paradigm shift. Front Behav Neurosci. 2015; 2015 Feb 20. PMID: 25750618

Song Y, Sanganahalli BG, Hyder F, Lin WC, Riera JJ: Distributions of Irritative Zones Are Related to Individual Alterations of Resting-State Networks in Focal Epilepsy. PLoS One. 2015; 2015 Jul 30. PMID: 26226628

Abdallah CG, Jiang L, De Feyter HM, Fasula M, Krystal JH, Rothman DL, Mason GF, Sanacora G: Glutamate metabolism in major depressive disorder. Am J Psychiatry. 2014 Dec 1; 2014 Oct 31. PMID: 25073688

Maritim S, Huang Y, Coman D, Hyder F: Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS). J Biol Inorg Chem. 2014 Dec; 2014 Oct 11. PMID: 25304046

Cheng DW, Ersahin D, Staib LH, Della Latta D, Giorgetti A, d'Errico F: Using SUV as a guide to 18F-FDG dose reduction. J Nucl Med. 2014 Dec; 2014 Nov 13. PMID: 25453048

Shulman RG, Hyder F, Rothman DL: Insights from neuroenergetics into the interpretation of functional neuroimaging: an alternative empirical model for studying the brain's support of behavior. J Cereb Blood Flow Metab. 2014 Nov; 2014 Aug 27. PMID: 25160670

Bagga P, Behar KL, Mason GF, De Feyter HM, Rothman DL, Patel AB: Characterization of cerebral glutamine uptake from blood in the mouse brain: implications for metabolic modeling of 13C NMR data. J Cereb Blood Flow Metab. 2014 Oct; 2014 Jul 30. PMID: 25074745

de Graaf RA, De Feyter HM, Rothman DL: High-sensitivity, broadband-decoupled 13 C MR spectroscopy in humans at 7T using two-dimensional heteronuclear single-quantum coherence. Magn Reson Med. 2014 Sep 29; 2014 Sep 29. PMID: 25264872

Lin AL, Coman D, Jiang L, Rothman DL, Hyder F: Caloric restriction impedes age-related decline of mitochondrial function and neuronal activity. J Cereb Blood Flow Metab. 2014 Sep; 2014 Jul 2. PMID: 24984898

Kelley BJ, Harel NY, Kim CY, Papademetris X, Coman D, Wang X, Hasan O, Kaufman A, Globinsky R, Staib LH, Cafferty WB, Hyder F, Strittmatter SM: Diffusion tensor imaging as a predictor of locomotor function after experimental spinal cord injury and recovery. J Neurotrauma. 2014 Aug 1; 2014 Jul 8. PMID: 24779685

Juchem C, Herman P, Sanganahalli BG, Brown PB, McIntyre S, Nixon TW, Green D, Hyder F, de Graaf RA: DYNAmic Multi-coIl TEchnique (DYNAMITE) shimming of the rat brain at 11.7 T. NMR Biomed. 2014 Aug; 2014 May 17. PMID: 24839167

Chowdhury GM, Jiang L, Rothman DL, Behar KL: The contribution of ketone bodies to basal and activity-dependent neuronal oxidation in vivo. J Cereb Blood Flow Metab. 2014 Jul; 2014 Apr 30. PMID: 24780902

Perry RJ, Zhang XM, Zhang D, Kumashiro N, Camporez JP, Cline GW, Rothman DL, Shulman GI: Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis. Nat Med. 2014 Jul; 2014 Jun 15. PMID: 24929951

de Graaf RA, Behar KL: Detection of cerebral NAD(+) by in vivo (1)H NMR spectroscopy. NMR Biomed. 2014 Jul; 2014 May 15. PMID: 24831866

de Graaf RA, Chowdhury GM, Behar KL: Quantification of high-resolution ¹H-[¹³C] NMR spectra from rat brain extracts. Anal Chem. 2014 May 20; 2014 May 9. PMID: 24773047

Lin AL, Rothman DL: What have novel imaging techniques revealed about metabolism in the aging brain? Future Neurol. 2014 May 1. PMID: 25214817

Coman D, Sanganahalli BG, Cheng D, McCarthy T, Rothman DL, Hyder F: Mapping phosphorylation rate of fluoro-deoxy-glucose in rat brain by (19)F chemical shift imaging. Magn Reson Imaging. 2014 May; 2013 Dec 14. PMID: 24581725

Patel AB, Lai JC, Chowdhury GM, Hyder F, Rothman DL, Shulman RG, Behar KL: Direct evidence for activity-dependent glucose phosphorylation in neurons with implications for the astrocyte-to-neuron lactate shuttle. Proc Natl Acad Sci U S A. 2014 Apr 8; 2014 Mar 26. PMID: 24706914

Pugh KR, Frost SJ, Rothman DL, Hoeft F, Del Tufo SN, Mason GF, Molfese PJ, Mencl WE, Grigorenko EL, Landi N, Preston JL, Jacobsen L, Seidenberg MS, Fulbright RK: Glutamate and choline levels predict individual differences in reading ability in emergent readers. J Neurosci. 2014 Mar 12. PMID: 24623786

Niciu MJ, Mason GF: Neuroimaging in Alcohol and Drug Dependence. Curr Behav Neurosci Rep. 2014 Mar 1. PMID: 24678450

Scafidi J, Hammond TR, Scafidi S, Ritter J, Jablonska B, Roncal M, Szigeti-Buck K, Coman D, Huang Y, McCarter RJ Jr, Hyder F, Horvath TL, Gallo V: Intranasal epidermal growth factor treatment rescues neonatal brain injury. Nature. 2014 Feb 13; 2013 Dec 25. PMID: 24390343

Befroy DE, Perry RJ, Jain N, Dufour S, Cline GW, Trimmer JK, Brosnan J, Rothman DL, Petersen KF, Shulman GI: Direct assessment of hepatic mitochondrial oxidative and anaplerotic fluxes in humans using dynamic 13C magnetic resonance spectroscopy. Nat Med. 2014 Jan; 2013 Dec 8. PMID: 24317120

Kwon SH, Scheinost D, Lacadie C, Benjamin J, Myers EH, Qiu M, Schneider KC, Rothman DL, Constable RT, Ment LR: GABA, resting-state connectivity and the developing brain. Neonatology. 2014; 2014 Jun 26. PMID: 24970028

Mishra AM, Bai X, Sanganahalli BG, Waxman SG, Shatillo O, Grohn O, Hyder F, Pitkänen A, Blumenfeld H: Decreased resting functional connectivity after traumatic brain injury in the rat. PLoS One. 2014; 2014 Apr 18. PMID: 24748279

Abdallah CG, Niciu MJ, Fenton LR, Fasula MK, Jiang L, Black A, Rothman DL, Mason GF, Sanacora G: Decreased occipital cortical glutamate levels in response to successful cognitive-behavioral therapy and pharmacotherapy for major depressive disorder. Psychother Psychosom. 2014; 2014 Aug 6. PMID: 25116726

Solecki W, Wickham RJ, Behrens S, Wang J, Zwerling B, Mason GF, Addy NA: Differential role of ventral tegmental area acetylcholine and N-methyl-D-aspartate receptors in cocaine-seeking. Neuropharmacology. 2013 Dec; 2013 Jul 11. PMID: 23850572

Juchem C, Green D, de Graaf RA: Multi-coil magnetic field modeling. J Magn Reson. 2013 Nov; 2013 Sep 13. PMID: 24095841

Wang J, Du H, Ma X, Pittman B, Castracane L, Li TK, Behar KL, Mason GF: Metabolic products of [2-(13) C]ethanol in the rat brain after chronic ethanol exposure. J Neurochem. 2013 Nov; 2013 Sep 23. PMID: 24033360

Coman D, de Graaf RA, Rothman DL, Hyder F: In vivo three-dimensional molecular imaging with Biosensor Imaging of Redundant Deviation in Shifts (BIRDS) at high spatiotemporal resolution. NMR Biomed. 2013 Nov; 2013 Jul 24. PMID: 23881869

Sanganahalli BG, Herman P, Behar KL, Blumenfeld H, Rothman DL, Hyder F: Functional MRI and neural responses in a rat model of Alzheimer's disease. Neuroimage. 2013 Oct 1; 2013 May 3. PMID: 23648961

Herman P, Sanganahalli BG, Blumenfeld H, Rothman DL, Hyder F: Quantitative basis for neuroimaging of cortical laminae with calibrated functional MRI. Proc Natl Acad Sci U S A. 2013 Sep 10; 2013 Aug 26. PMID: 23980158

De Feyter HM, Mason GF, Shulman GI, Rothman DL, Petersen KF: Increased brain lactate concentrations without increased lactate oxidation during hypoglycemia in type 1 diabetic individuals. Diabetes. 2013 Sep; 2013 May 28. PMID: 23715622

Gulanski BI, De Feyter HM, Page KA, Belfort-DeAguiar R, Mason GF, Rothman DL, Sherwin RS: Increased brain transport and metabolism of acetate in hypoglycemia unawareness. J Clin Endocrinol Metab. 2013 Sep; 2013 Jun 24. PMID: 23796565

Mishra AM, Bai X, Motelow JE, Desalvo MN, Danielson N, Sanganahalli BG, Hyder F, Blumenfeld H: Increased resting functional connectivity in spike-wave epilepsy in WAG/Rij rats. Epilepsia. 2013 Jul. PMID: 23815571

Sanganahalli BG, Herman P, Hyder F, Kannurpatti SS: Mitochondrial calcium uptake capacity modulates neocortical excitability. J Cereb Blood Flow Metab. 2013 Jul; 2013 Apr 17. PMID: 23591650

Herzog RI, Jiang L, Herman P, Zhao C, Sanganahalli BG, Mason GF, Hyder F, Rothman DL, Sherwin RS, Behar KL: Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia. J Clin Invest. 2013 May; 2013 Apr 1. PMID: 23543056

Sanganahalli BG, Herman P, Hyder F, Kannurpatti SS: Mitochondrial functional state impacts spontaneous neocortical activity and resting state FMRI. PLoS One. 2013; 2013 May 1. PMID: 23650561

Jiang L, Gulanski BI, De Feyter HM, Weinzimer SA, Pittman B, Guidone E, Koretski J, Harman S, Petrakis IL, Krystal JH, Mason GF: Increased brain uptake and oxidation of acetate in heavy drinkers. J Clin Invest. 2013 Apr; 2013 Mar 8. PMID: 23478412

Hyder F, Fulbright RK, Shulman RG, Rothman DL: Glutamatergic function in the resting awake human brain is supported by uniformly high oxidative energy. J Cereb Blood Flow Metab. 2013 Mar; 2013 Jan 9. PMID: 23299240

Hyder F, Rothman DL, Bennett MR: Cortical energy demands of signaling and nonsignaling components in brain are conserved across mammalian species and activity levels. Proc Natl Acad Sci U S A. 2013 Feb 26; 2013 Jan 14. PMID: 23319606

Stockmann JP, Galiana G, Tam L, Juchem C, Nixon TW, Constable RT: In vivo O-Space imaging with a dedicated 12 cm Z2 insert coil on a human 3T scanner using phase map calibration. Magn Reson Med. 2013 Feb; 2012 May 14. PMID: 22585546

Bailey CJ, Sanganahalli BG, Herman P, Blumenfeld H, Gjedde A, Hyder F: Analysis of time and space invariance of BOLD responses in the rat visual system. Cereb Cortex. 2013 Jan; 2012 Jan 31. PMID: 22298731

Lacar B, Herman P, Platel JC, Kubera C, Hyder F, Bordey A: Neural progenitor cells regulate capillary blood flow in the postnatal subventricular zone. J Neurosci. 2012 Nov 14. PMID: 23152626

Carlyle BC, Duque A, Kitchen RR, Bordner KA, Coman D, Doolittle E, Papademetris X, Hyder F, Taylor JR, Simen AA: Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits. Dev Psychopathol. 2012 Nov. PMID: 23062306

Befroy DE, Rothman DL, Petersen KF, Shulman GI: ³¹P-magnetization transfer magnetic resonance spectroscopy measurements of in vivo metabolism. Diabetes. 2012 Nov. PMID: 23093656

Rothman DL, De Feyter HM, Maciejewski PK, Behar KL: Is there in vivo evidence for amino acid shuttles carrying ammonia from neurons to astrocytes? Neurochem Res. 2012 Nov; 2012 Oct 27. PMID: 23104556

Eid T, Behar K, Dhaher R, Bumanglag AV, Lee TS: Roles of glutamine synthetase inhibition in epilepsy. Neurochem Res. 2012 Nov; 2012 Apr 10. PMID: 22488332

Hyder F, Rothman DL: Quantitative fMRI and oxidative neuroenergetics. Neuroimage. 2012 Aug 15; 2012 Apr 19. PMID: 22542993

Chowdhury GM, Behar KL, Cho W, Thomas MA, Rothman DL, Sanacora G: ¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism. Biol Psychiatry. 2012 Jun 1; 2011 Dec 9. PMID: 22169441

Morgan PT, Pace-Schott EF, Mason GF, Forselius E, Fasula M, Valentine GW, Sanacora G: Cortical GABA levels in primary insomnia. Sleep. 2012 Jun 1; 2012 Jun 1. PMID: 22654200

Duque A, Coman D, Carlyle BC, Bordner KA, George ED, Papademetris X, Hyder F, Simen AA: Neuroanatomical changes in a mouse model of early life neglect. Brain Struct Funct. 2012 Apr; 2011 Oct 8. PMID: 21984312

Eke A, Herman P, Sanganahalli BG, Hyder F, Mukli P, Nagy Z: Pitfalls in Fractal Time Series Analysis: fMRI BOLD as an Exemplary Case. Front Physiol. 2012; 2012 Nov 15. PMID: 23227008

Lacar B, Herman P, Hartman NW, Hyder F, Bordey A: S phase entry of neural progenitor cells correlates with increased blood flow in the young subventricular zone. PLoS One. 2012; 2012 Feb 16. PMID: 22359646

Jiang L, Mason GF, Rothman DL, de Graaf RA, Behar KL: Cortical substrate oxidation during hyperketonemia in the fasted anesthetized rat in vivo. J Cereb Blood Flow Metab. 2011 Dec; 2011 Jul 6. PMID: 21731032

Coman D, Kiefer GE, Rothman DL, Sherry AD, Hyder F: A lanthanide complex with dual biosensing properties: CEST (chemical exchange saturation transfer) and BIRDS (biosensor imaging of redundant deviation in shifts) with europium DOTA-tetraglycinate. NMR Biomed. 2011 Dec. PMID: 22020775

Mishra AM, Ellens DJ, Schridde U, Motelow JE, Purcaro MJ, DeSalvo MN, Enev M, Sanganahalli BG, Hyder F, Blumenfeld H: Where fMRI and electrophysiology agree to disagree: corticothalamic and striatal activity patterns in the WAG/Rij rat. J Neurosci. 2011 Oct 19. PMID: 22016539

Herman P, Sanganahalli BG, Hyder F, Eke A: Fractal analysis of spontaneous fluctuations of the BOLD signal in rat brain. Neuroimage. 2011 Oct 15; 2011 Jul 12. PMID: 21777682

Juchem C, Nixon TW, McIntyre S, Boer VO, Rothman DL, de Graaf RA: Dynamic multi-coil shimming of the human brain at 7 T. J Magn Reson. 2011 Oct; 2011 Jul 23. PMID: 21824794

de Graaf RA, Rothman DL, Behar KL: State of the art direct 13C and indirect 1H-[13C] NMR spectroscopy in vivo. A practical guide. NMR Biomed. 2011 Oct; 2011 Aug 23. PMID: 21919099

Rothman DL, De Feyter HM, de Graaf RA, Mason GF, Behar KL: 13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR Biomed. 2011 Oct; 2011 Aug 31. PMID: 21882281

Juchem C, Brown PB, Nixon TW, McIntyre S, Rothman DL, de Graaf RA: Multicoil shimming of the mouse brain. Magn Reson Med. 2011 Sep; 2011 Mar 25. PMID: 21442653

Herzog RI, Sherwin RS, Rothman DL: Insulin-induced hypoglycemia and its effect on the brain: unraveling metabolism by in vivo nuclear magnetic resonance. Diabetes. 2011 Jul. PMID: 21709281

Cosgrove KP, Esterlis I, Mason GF, Bois F, O'Malley SS, Krystal JH: Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence. Neuropharmacology. 2011 Jun; 2011 Jan 27. PMID: 21276806

Befroy DE, Shulman GI: Magnetic resonance spectroscopy studies of human metabolism. Diabetes. 2011 May. PMID: 21525507

Hyder F, Rothman DL: Evidence for the importance of measuring total brain activity in neuroimaging. Proc Natl Acad Sci U S A. 2011 Apr 5; 2011 Mar 24. PMID: 21441108

Alves TC, Befroy DE, Kibbey RG, Kahn M, Codella R, Carvalho RA, Falk Petersen K, Shulman GI: Regulation of hepatic fat and glucose oxidation in rats with lipid-induced hepatic insulin resistance. Hepatology. 2011 Apr; 2011 Mar 11. PMID: 21400553

Valentine GW, Mason GF, Gomez R, Fasula M, Watzl J, Pittman B, Krystal JH, Sanacora G: The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [(1)H]-MRS. Psychiatry Res. 2011 Feb 28; 2011 Jan 12. PMID: 21232924

de Graaf RA, Chowdhury GM, Behar KL: Quantification of high-resolution (1)H NMR spectra from rat brain extracts. Anal Chem. 2011 Jan 1; 2010 Dec 13. PMID: 21142125

Palejev D, Hwang W, Landi N, Eastman M, Frost SJ, Fulbright RK, Kidd JR, Kidd KK, Mason GF, Mencl WE, Yrigollen C, Pugh KR, Grigorenko EL: An application of the elastic net for an endophenotype analysis. Behav Genet. 2011 Jan; 2011 Jan 13. PMID: 21229297

Hyder F, Herman P, Sanganahalli BG, Coman D, Blumenfeld H, Rothman DL: Role of ongoing, intrinsic activity of neuronal populations for quantitative neuroimaging of functional magnetic resonance imaging-based networks. Brain Connect. 2011. PMID: 22433047

Shulman RG: A philosophical analysis of neuroenergetics. Front Neuroenergetics. 2011; 2011 Nov 18. PMID: 22121346

Boumezbeur F, Petersen KF, Cline GW, Mason GF, Behar KL, Shulman GI, Rothman DL: The contribution of blood lactate to brain energy metabolism in humans measured by dynamic 13C nuclear magnetic resonance spectroscopy. J Neurosci. 2010 Oct 20. PMID: 20962220

Juchem C, Nixon TW, Diduch P, Rothman DL, Starewicz P, de Graaf RA: Dynamic Shimming of the Human Brain at 7 Tesla. Concepts Magn Reson Part B Magn Reson Eng. 2010 Jul 6. PMID: 20657809

Leuenroth SJ, Bencivenga N, Chahboune H, Hyder F, Crews CM: Triptolide reduces cyst formation in a neonatal to adult transition Pkd1 model of ADPKD. Nephrol Dial Transplant. 2010 Jul; 2010 Feb 4. PMID: 20139063

Hyder F, Rothman DL: Neuronal correlate of BOLD signal fluctuations at rest: err on the side of the baseline. Proc Natl Acad Sci U S A. 2010 Jun 15; 2010 Jun 8. PMID: 20534504

Patel AB, de Graaf RA, Rothman DL, Behar KL, Mason GF: Evaluation of cerebral acetate transport and metabolic rates in the rat brain in vivo using 1H-[13C]-NMR. J Cereb Blood Flow Metab. 2010 Jun; 2010 Feb 3. PMID: 20125180

Juchem C, Nixon TW, McIntyre S, Rothman DL, de Graaf RA: Magnetic field modeling with a set of individual localized coils. J Magn Reson. 2010 Jun; 2010 Mar 11. PMID: 20347360

Wang J, Jiang L, Jiang Y, Ma X, Chowdhury GM, Mason GF: Regional metabolite levels and turnover in the awake rat brain under the influence of nicotine. J Neurochem. 2010 Jun; 2010 Mar 14. PMID: 20345764

Banasr M, Chowdhury GM, Terwilliger R, Newton SS, Duman RS, Behar KL, Sanacora G: Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole. Mol Psychiatry. 2010 May; 2008 Sep 30. PMID: 18825147

DeSalvo MN, Schridde U, Mishra AM, Motelow JE, Purcaro MJ, Danielson N, Bai X, Hyder F, Blumenfeld H: Focal BOLD fMRI changes in bicuculline-induced tonic-clonic seizures in the rat. Neuroimage. 2010 Apr 15; 2010 Jan 14. PMID: 20079442

Coman D, Trubel HK, Hyder F: Brain temperature by Biosensor Imaging of Redundant Deviation in Shifts (BIRDS): comparison between TmDOTP5- and TmDOTMA-. NMR Biomed. 2010 Apr. PMID: 19957287

Fitzgerald TN, Muto A, Fancher TT, Brown PB, Martin KA, Muhs BE, Rothman DL, Constable RT, Sampath S, Dardik A: Surgically implantable magnetic resonance angiography coils improve resolution to allow visualization of blood flow dynamics. Ann Vasc Surg. 2010 Feb; 2009 Dec 29. PMID: 20036497

Hyder F, Sanganahalli BG, Herman P, Coman D, Maandag NJ, Behar KL, Blumenfeld H, Rothman DL: Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms. Front Neuroenergetics. 2010; 2010 Aug 19. PMID: 20838476

Boumezbeur F, Mason GF, de Graaf RA, Behar KL, Cline GW, Shulman GI, Rothman DL, Petersen KF: Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy. J Cereb Blood Flow Metab. 2010 Jan; 2009 Sep 30. PMID: 19794401

Juchem C, Nixon TW, McIntyre S, Rothman DL, de Graaf RA: Magnetic field homogenization of the human prefrontal cortex with a set of localized electrical coils. Magn Reson Med. 2010 Jan. PMID: 19918909

Chahboune H, Ment LR, Stewart WB, Rothman DL, Vaccarino FM, Hyder F, Schwartz ML: Hypoxic injury during neonatal development in murine brain: correlation between in vivo DTI findings and behavioral assessment. Cereb Cortex. 2009 Dec; 2009 Apr 20. PMID: 19380380

Englot DJ, Modi B, Mishra AM, DeSalvo M, Hyder F, Blumenfeld H: Cortical deactivation induced by subcortical network dysfunction in limbic seizures. J Neurosci. 2009 Oct 14. PMID: 19828814

Shulman RG, Hyder F, Rothman DL: Baseline brain energy supports the state of consciousness. Proc Natl Acad Sci U S A. 2009 Jul 7; 2009 Jun 19. PMID: 19549837

Jiang L, Herzog RI, Mason GF, de Graaf RA, Rothman DL, Sherwin RS, Behar KL: Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo. Diabetes. 2009 Jun; 2009 Mar 10. PMID: 19276443

Herman P, Sanganahalli BG, Blumenfeld H, Hyder F: Cerebral oxygen demand for short-lived and steady-state events. J Neurochem. 2009 May. PMID: 19393011

de Graaf RA, Chowdhury GM, Brown PB, Rothman DL, Behar KL: In situ 3D magnetic resonance metabolic imaging of microwave-irradiated rodent brain: a new tool for metabolomics research. J Neurochem. 2009 Apr; 2009 Feb 7. PMID: 19200336

Musa-Aziz R, Jiang L, Chen LM, Behar KL, Boron WF: Concentration-dependent effects on intracellular and surface pH of exposing Xenopus oocytes to solutions containing NH3/NH4(+). J Membr Biol. 2009 Mar; 2009 Feb 26. PMID: 19242745

Sanganahalli BG, Herman P, Blumenfeld H, Hyder F: Oxidative neuroenergetics in event-related paradigms. J Neurosci. 2009 Feb 11. PMID: 19211878

Coman D, Trubel HK, Rycyna RE, Hyder F: Brain temperature and pH measured by (1)H chemical shift imaging of a thulium agent. NMR Biomed. 2009 Feb. PMID: 19130468

Herman P, Sanganahalli BG, Hyder F: Multimodal measurements of blood plasma and red blood cell volumes during functional brain activation. J Cereb Blood Flow Metab. 2009 Jan; 2008 Sep 3. PMID: 18766196

Befroy DE, Falk Petersen K, Rothman DL, Shulman GI: Assessment of in vivo mitochondrial metabolism by magnetic resonance spectroscopy. Methods Enzymol. 2009. PMID: 19426879

Sanganahalli BG, Bailey CJ, Herman P, Hyder F: Tactile and non-tactile sensory paradigms for fMRI and neurophysiologic studies in rodents. Methods Mol Biol. 2009. PMID: 18839094

Herman P, Kocsis L, Eke A: Fractal characterization of complexity in dynamic signals: application to cerebral hemodynamics. Methods Mol Biol. 2009. PMID: 18839086

Hyder F: Dynamic imaging of brain function. Methods Mol Biol. 2009. PMID: 18839085

Choi CS, Befroy DE, Codella R, Kim S, Reznick RM, Hwang YJ, Liu ZX, Lee HY, Distefano A, Samuel VT, Zhang D, Cline GW, Handschin C, Lin J, Petersen KF, Spiegelman BM, Shulman GI: Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proc Natl Acad Sci U S A. 2008 Dec 16; 2008 Dec 9. PMID: 19066218

Chowdhury GM, Banasr M, de Graaf RA, Rothman DL, Behar KL, Sanacora G: Chronic riluzole treatment increases glucose metabolism in rat prefrontal cortex and hippocampus. J Cereb Blood Flow Metab. 2008 Dec; 2008 Jul 16. PMID: 18628780

De Feyter HM, Lenaers E, Houten SM, Schrauwen P, Hesselink MK, Wanders RJ, Nicolay K, Prompers JJ: Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxidative capacity throughout the pathogenesis of type 2 diabetes. FASEB J. 2008 Nov; 2008 Jul 24. PMID: 18653763

Befroy DE, Petersen KF, Dufour S, Mason GF, Rothman DL, Shulman GI: Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals. Proc Natl Acad Sci U S A. 2008 Oct 28; 2008 Oct 20. PMID: 18936488

Englot DJ, Mishra AM, Mansuripur PK, Herman P, Hyder F, Blumenfeld H: Remote effects of focal hippocampal seizures on the rat neocortex. J Neurosci. 2008 Sep 3. PMID: 18768701

Schridde U, Khubchandani M, Motelow JE, Sanganahalli BG, Hyder F, Blumenfeld H: Negative BOLD with large increases in neuronal activity. Cereb Cortex. 2008 Aug; 2007 Dec 5. PMID: 18063563

Lesnik GT, Remenschneider AK, Herman P, Ross A, Ross DA: Capillary blood gas: a novel means of assessing free flap perfusion in an animal model. Otolaryngol Head Neck Surg. 2008 Aug. PMID: 18656724

de Graaf RA, Brown PB, Rothman DL, Behar KL: Natural abundance (17)O NMR spectroscopy of rat brain in vivo. J Magn Reson. 2008 Jul; 2008 May 5. PMID: 18456525

Nixon TW, McIntyre S, Rothman DL, de Graaf RA: Compensation of gradient-induced magnetic field perturbations. J Magn Reson. 2008 Jun; 2008 Feb 23. PMID: 18329304

Sanganahalli BG, Herman P, Hyder F: Frequency-dependent tactile responses in rat brain measured by functional MRI. NMR Biomed. 2008 May. PMID: 18435491

Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R: It is time to take a stand for medical research and against terrorism targeting medical scientists. Biol Psychiatry. 2008 Apr 15. PMID: 18371494

Kim H, Taksali SE, Dufour S, Befroy D, Goodman TR, Petersen KF, Shulman GI, Caprio S, Constable RT: Comparative MR study of hepatic fat quantification using single-voxel proton spectroscopy, two-point dixon and three-point IDEAL. Magn Reson Med. 2008 Mar. PMID: 18306404

Maciejewski PK, Rothman DL: Proposed cycles for functional glutamate trafficking in synaptic neurotransmission. Neurochem Int. 2008 Mar-Apr; 2007 Oct 2. PMID: 18006192

Maandag NJ, Coman D, Sanganahalli BG, Herman P, Smith AJ, Blumenfeld H, Shulman RG, Hyder F: Energetics of neuronal signaling and fMRI activity. Proc Natl Acad Sci U S A. 2007 Dec 18; 2007 Dec 13. PMID: 18079290

Chowdhury GM, Patel AB, Mason GF, Rothman DL, Behar KL: Glutamatergic and GABAergic neurotransmitter cycling and energy metabolism in rat cerebral cortex during postnatal development. J Cereb Blood Flow Metab. 2007 Dec; 2007 Apr 18. PMID: 17440492

Chowdhury GM, Gupta M, Gibson KM, Patel AB, Behar KL: Altered cerebral glucose and acetate metabolism in succinic semialdehyde dehydrogenase-deficient mice: evidence for glial dysfunction and reduced glutamate/glutamine cycling. J Neurochem. 2007 Dec; 2007 Sep 13. PMID: 17854388

Qin Q, Gore JC, de Graaf RA, Does MD: Quantitative T2 measurement of a single voxel with arbitrary shape using pinwheel excitation and CPMG acquisition. MAGMA. 2007 Dec; 2007 Nov 13. PMID: 17999101

de Graaf RA, Rothman DL, Behar KL: High resolution NMR spectroscopy of rat brain in vivo through indirect zero-quantum-coherence detection. J Magn Reson. 2007 Aug; 2007 Jun 10. PMID: 17587617

Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, Cline GW, Befroy D, Zemany L, Kahn BB, Papademetris X, Rothman DL, Shulman GI: The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A. 2007 Jul 31; 2007 Jul 18. PMID: 17640906

Qin Q, Gore JC, Does MD, Avison MJ, de Graaf RA: 2D arbitrary shape-selective excitation summed spectroscopy (ASSESS). Magn Reson Med. 2007 Jul. PMID: 17659614

Shulman RG, Rothman DL, Hyder F: A BOLD search for baseline. Neuroimage. 2007 Jun; 2007 Jan 16. PMID: 17223362

Befroy DE, Petersen KF, Dufour S, Mason GF, de Graaf RA, Rothman DL, Shulman GI: Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes. 2007 May; 2007 Feb 7. PMID: 17287462

Chahboune H, Ment LR, Stewart WB, Ma X, Rothman DL, Hyder F: Neurodevelopment of C57B/L6 mouse brain assessed by in vivo diffusion tensor imaging. NMR Biomed. 2007 May. PMID: 17451176

Kida I, Rothman DL, Hyder F: Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration. J Cereb Blood Flow Metab. 2007 Apr; 2006 Oct 11. PMID: 17033688

Koch KM, Sacolick LI, Nixon TW, McIntyre S, Rothman DL, de Graaf RA: Dynamically shimmed multivoxel 1H magnetic resonance spectroscopy and multislice magnetic resonance spectroscopic imaging of the human brain. Magn Reson Med. 2007 Mar. PMID: 17326186

Sacolick LI, Rothman DL, de Graaf RA: Adiabatic refocusing pulses for volume selection in magnetic resonance spectroscopic imaging. Magn Reson Med. 2007 Mar. PMID: 17326179

Reznick RM, Zong H, Li J, Morino K, Moore IK, Yu HJ, Liu ZX, Dong J, Mustard KJ, Hawley SA, Befroy D, Pypaert M, Hardie DG, Young LH, Shulman GI: Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metab. 2007 Feb. PMID: 17276357

Mason GF: Get sober; stay sober. Brain. 2007 Jan. PMID: 17178741

Mason GF, Petersen KF, de Graaf RA, Shulman GI, Rothman DL: Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose. J Neurochem. 2007 Jan; 2006 Oct 31. PMID: 17076763

Koch KM, Papademetris X, Rothman DL, de Graaf RA: Rapid calculations of susceptibility-induced magnetostatic field perturbations for in vivo magnetic resonance. Phys Med Biol. 2006 Dec 21; 2006 Nov 27. PMID: 17148824

Carpenter TO, DeLucia MC, Zhang JH, Bejnerowicz G, Tartamella L, Dziura J, Petersen KF, Befroy D, Cohen D: A randomized controlled study of effects of dietary magnesium oxide supplementation on bone mineral content in healthy girls. J Clin Endocrinol Metab. 2006 Dec; 2006 Oct 3. PMID: 17018656

Petersen KF, Dufour S, Feng J, Befroy D, Dziura J, Dalla Man C, Cobelli C, Shulman GI: Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men. Proc Natl Acad Sci U S A. 2006 Nov 28; 2006 Nov 17. PMID: 17114290

Vartanian LR, Herman CP, Polivy J: Does regulatory focus play a role in dietary restraint? Eat Behav. 2006 Nov; 2005 Nov 21. PMID: 17056409

Mason GF, Krystal JH: MR spectroscopy: its potential role for drug development for the treatment of psychiatric diseases. NMR Biomed. 2006 Oct. PMID: 16986118

Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J: Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Arch Gen Psychiatry. 2006 Sep. PMID: 16952998

Koch KM, Brown PB, Rothman DL, de Graaf RA: Sample-specific diamagnetic and paramagnetic passive shimming. J Magn Reson. 2006 Sep; 2006 Jun 30. PMID: 16814580

de Graaf RA, Brown PB, McIntyre S, Nixon TW, Behar KL, Rothman DL: High magnetic field water and metabolite proton T1 and T2 relaxation in rat brain in vivo. Magn Reson Med. 2006 Aug. PMID: 16767752

Amin Z, Mason GF, Cavus I, Krystal JH, Rothman DL, Epperson CN: The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women. Pharmacol Biochem Behav. 2006 Aug; 2006 Jul 24. PMID: 16860856

Hyder F, Patel AB, Gjedde A, Rothman DL, Behar KL, Shulman RG: Neuronal-glial glucose oxidation and glutamatergic-GABAergic function. J Cereb Blood Flow Metab. 2006 Jul; 2006 Jan 11. PMID: 16407855

Song H, Roa DE, Yue N, d'Errico F, Chen Z, Nath R: Application of Gafchromic film in the dosimetry of an intravascular brachytherapy source. Med Phys. 2006 Jul. PMID: 16898455

Schafer JR, Kida I, Xu F, Rothman DL, Hyder F: Reproducibility of odor maps by fMRI in rodents. Neuroimage. 2006 Jul 1; 2006 Apr 24. PMID: 16632382

Koch KM, McIntyre S, Nixon TW, Rothman DL, de Graaf RA: Dynamic shim updating on the human brain. J Magn Reson. 2006 Jun; 2006 Mar 30. PMID: 16574443

Epperson CN, Gueorguieva R, Czarkowski KA, Stiklus S, Sellers E, Krystal JH, Rothman DL, Mason GF: Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study. Psychopharmacology (Berl). 2006 Jun; 2006 May 3. PMID: 16724188

Vartanian LR, Herman CP: Beliefs about the determinants of body weight predict dieting and exercise behavior. Eat Behav. 2006 May; 2005 Aug 30. PMID: 16600845

de Graaf RA, Patel AB, Rothman DL, Behar KL: Acute regulation of steady-state GABA levels following GABA-transaminase inhibition in rat cerebral cortex. Neurochem Int. 2006 May-Jun; 2006 Mar 3. PMID: 16517019

Mason GF, Petersen KF, Lebon V, Rothman DL, Shulman GI: Increased brain monocarboxylic acid transport and utilization in type 1 diabetes. Diabetes. 2006 Apr. PMID: 16567513

Patel AB, de Graaf RA, Martin DL, Battaglioli G, Behar KL: Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. J Neurochem. 2006 Apr; 2006 Mar 15. PMID: 16539672

Petroff OA, Hyder F, Rothman DL, Mattson RH: Brain homocarnosine and seizure control of patients taking gabapentin or topiramate. Epilepsia. 2006 Mar. PMID: 16529611

Sanacora G, Fenton LR, Fasula MK, Rothman DL, Levin Y, Krystal JH, Mason GF: Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy. Biol Psychiatry. 2006 Feb 1; 2005 Sep 1. PMID: 16139814

Mason GF, Petrakis IL, de Graaf RA, Gueorguieva R, Guidone E, Coric V, Epperson CN, Rothman DL, Krystal JH: Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking. Biol Psychiatry. 2006 Jan 1; 2005 Nov 14. PMID: 16289397

Hermán P, Trübel HK, Hyder F: A multiparametric assessment of oxygen efflux from the brain. J Cereb Blood Flow Metab. 2006 Jan. PMID: 15973353

Trübel HK, Sacolick LI, Hyder F: Regional temperature changes in the brain during somatosensory stimulation. J Cereb Blood Flow Metab. 2006 Jan. PMID: 15959461

Kida I, Smith AJ, Blumenfeld H, Behar KL, Hyder F: Lamotrigine suppresses neurophysiological responses to somatosensory stimulation in the rodent. Neuroimage. 2006 Jan 1; 2005 Aug 19. PMID: 16112588

d'Errico F: Status of radiation detection with superheated emulsions. Radiat Prot Dosimetry. 2006; 2006 Jul 25. PMID: 16868012

Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI: Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. J Clin Invest. 2005 Dec; 2005 Nov 10. PMID: 16284649

Shulman RG: Glycogen turnover forms lactate during exercise. Exerc Sport Sci Rev. 2005 Oct. PMID: 16239831

Xu F, Schaefer M, Kida I, Schafer J, Liu N, Rothman DL, Hyder F, Restrepo D, Shepherd GM: Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones. J Comp Neurol. 2005 Sep 5. PMID: 16025460

Schafer JR, Kida I, Rothman DL, Hyder F, Xu F: Adaptation in the rodent olfactory bulb measured by fMRI. Magn Reson Med. 2005 Aug. PMID: 16032685

Safriel Y, Pol-Rodriguez M, Novotny EJ, Rothman DL, Fulbright RK: Reference values for long echo time MR spectroscopy in healthy adults. AJNR Am J Neuroradiol. 2005 Jun-Jul. PMID: 15956513

de Graaf RA: Theoretical and experimental evaluation of broadband decoupling techniques for in vivo nuclear magnetic resonance spectroscopy. Magn Reson Med. 2005 Jun. PMID: 15906279

Patel AB, de Graaf RA, Mason GF, Rothman DL, Shulman RG, Behar KL: The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo. Proc Natl Acad Sci U S A. 2005 Apr 12; 2005 Apr 4. PMID: 15809416

Petersen KF, Dufour S, Befroy D, Lehrke M, Hendler RE, Shulman GI: Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes. Diabetes. 2005 Mar. PMID: 15734833

Epperson CN, O'Malley S, Czarkowski KA, Gueorguieva R, Jatlow P, Sanacora G, Rothman DL, Krystal JH, Mason GF: Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy. Biol Psychiatry. 2005 Jan 1. PMID: 15607299

Qin Q, de Graaf R, Does M, Gore J: Calculation of RF Peak Power for 2D Arbitrary Shape Excitation in MRI. Conf Proc IEEE Eng Med Biol Soc. 2005. PMID: 17282444

Papademetris X, Shkarin P, Staib LH, Behar KL: Regional whole body fat quantification in mice. Inf Process Med Imaging. 2005. PMID: 17354710

Patel AB, Chowdhury GM, de Graaf RA, Rothman DL, Shulman RG, Behar KL: Cerebral pyruvate carboxylase flux is unaltered during bicuculline-seizures. J Neurosci Res. 2005 Jan 1-15. PMID: 15562501

Kida I, Maciejewski PK, Hyder F: Dynamic imaging of perfusion and oxygenation by functional magnetic resonance imaging. J Cereb Blood Flow Metab. 2004 Dec. PMID: 15625411

Hyder F: Neuroimaging with calibrated FMRI. Stroke. 2004 Nov; 2004 Sep 23. PMID: 15388903

Trübel H, Herman P, Kampmann C, Huth R, Maciejewski PK, Novotny E, Hyder F: A novel approach for selective brain cooling: implications for hypercapnia and seizure activity. Intensive Care Med. 2004 Sep; 2004 Jun 8. PMID: 15185071

Nersesyan H, Herman P, Erdogan E, Hyder F, Blumenfeld H: Relative changes in cerebral blood flow and neuronal activity in local microdomains during generalized seizures. J Cereb Blood Flow Metab. 2004 Sep. PMID: 15356426

Patel AB, de Graaf RA, Mason GF, Kanamatsu T, Rothman DL, Shulman RG, Behar KL: Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation. J Cereb Blood Flow Metab. 2004 Sep. PMID: 15356418

de Graaf RA, Mason GF, Patel AB, Rothman DL, Behar KL: Regional glucose metabolism and glutamatergic neurotransmission in rat brain in vivo. Proc Natl Acad Sci U S A. 2004 Aug 24; 2004 Aug 13. PMID: 15310848

Shulman RG, Rothman DL, Behar KL, Hyder F: Energetic basis of brain activity: implications for neuroimaging. Trends Neurosci. 2004 Aug. PMID: 15271497

Samuel VT, Liu ZX, Qu X, Elder BD, Bilz S, Befroy D, Romanelli AJ, Shulman GI: Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J Biol Chem. 2004 Jul 30; 2004 May 27. PMID: 15166226

Sanacora G, Gueorguieva R, Epperson CN, Wu YT, Appel M, Rothman DL, Krystal JH, Mason GF: Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. Arch Gen Psychiatry. 2004 Jul. PMID: 15237082

Nersesyan H, Hyder F, Rothman DL, Blumenfeld H: Dynamic fMRI and EEG recordings during spike-wave seizures and generalized tonic-clonic seizures in WAG/Rij rats. J Cereb Blood Flow Metab. 2004 Jun. PMID: 15181366

Roa DE, Song H, Yue N, d'Errico F, Nath R: Dosimetric characteristics of the Novoste Beta-Cath 90Sr/Y source trains at submillimeter distances. Med Phys. 2004 May. PMID: 15191319

Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI: Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med. 2004 Feb 12. PMID: 14960743

Schafer JR, Fell DA, Rothman D, Shulman RG: Protein phosphorylation can regulate metabolite concentrations rather than control flux: the example of glycogen synthase. Proc Natl Acad Sci U S A. 2004 Feb 10; 2004 Jan 26. PMID: 14745035

Zhang XM, Patel AB, de Graaf RA, Behar KL: Determination of liposomal encapsulation efficiency using proton NMR spectroscopy. Chem Phys Lipids. 2004 Jan. PMID: 14706745

Mason GF, Rothman DL: Basic principles of metabolic modeling of NMR (13)C isotopic turnover to determine rates of brain metabolism in vivo. Metab Eng. 2004 Jan. PMID: 14734257

Liu N, Xu F, Marenco L, Hyder F, Miller P, Shepherd GM: Informatics approaches to functional MRI odor mapping of the rodent olfactory bulb: OdorMapBuilder and OdorMapDB. Neuroinformatics. 2004. PMID: 15067166

d'Errico F, Bos AJ: Passive detectors for neutron personal dosimetry: state of the art. Radiat Prot Dosimetry. 2004. PMID: 15353644

Patel AB, De Graaf RA, Mason GF, Rothman DL, Shulman RG, Behar KL: Coupling of glutamatergic neurotransmission and neuronal glucose oxidation over the entire range of cerebral cortex activity. Ann N Y Acad Sci. 2003 Nov. PMID: 14684486

Sanacora G, Rothman DL, Mason G, Krystal JH: Clinical studies implementing glutamate neurotransmission in mood disorders. Ann N Y Acad Sci. 2003 Nov. PMID: 14684453

Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB: Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. Biol Psychiatry. 2003 Oct 15. PMID: 14550678

de Graaf RA, Mason GF, Patel AB, Behar KL, Rothman DL: In vivo 1H-[13C]-NMR spectroscopy of cerebral metabolism. NMR Biomed. 2003 Oct-Nov. PMID: 14679499

Xu F, Liu N, Kida I, Rothman DL, Hyder F, Shepherd GM: Odor maps of aldehydes and esters revealed by functional MRI in the glomerular layer of the mouse olfactory bulb. Proc Natl Acad Sci U S A. 2003 Sep 16; 2003 Sep 8. PMID: 12963819

Price TB, Krishnan-Sarin S, Rothman DL: Smoking impairs muscle recovery from exercise. Am J Physiol Endocrinol Metab. 2003 Jul; 2003 Mar 11. PMID: 12637259

Krystal JH, Petrakis IL, Mason G, Trevisan L, D'Souza DC: N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol Ther. 2003 Jul. PMID: 12804700

Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, Shulman GI: Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science. 2003 May 16. PMID: 12750520

de Graaf RA, Behar KL: Quantitative 1H NMR spectroscopy of blood plasma metabolites. Anal Chem. 2003 May 1. PMID: 12720347

Trübel HK, Maciejewski PK, Farber JH, Hyder F: Brain temperature measured by 1H-NMR in conjunction with a lanthanide complex. J Appl Physiol (1985). 2003 Apr; 2002 Nov 27. PMID: 12626478

Mason GF: Magnetic resonance spectroscopy for studies of neurotransmission in vivo. Psychopharmacol Bull. 2003 Spring. PMID: 14566212

Sanacora G, Mason GF, Rothman DL, Hyder F, Ciarcia JJ, Ostroff RB, Berman RM, Krystal JH: Increased cortical GABA concentrations in depressed patients receiving ECT. Am J Psychiatry. 2003 Mar. PMID: 12611844

Shulman RG, Hyder F, Rothman DL: Cerebral metabolism and consciousness. C R Biol. 2003 Mar. PMID: 12806834

de Graaf RA, Brown PB, McIntyre S, Rothman DL, Nixon TW: Dynamic shim updating (DSU) for multislice signal acquisition. Magn Reson Med. 2003 Mar. PMID: 12594742

Mason GF, Falk Petersen K, de Graaf RA, Kanamatsu T, Otsuki T, Shulman GI, Rothman DL: A comparison of (13)C NMR measurements of the rates of glutamine synthesis and the tricarboxylic acid cycle during oral and intravenous administration of [1-(13)C]glucose. Brain Res Brain Res Protoc. 2003 Feb. PMID: 12565689

de Graaf RA, Rothman DL, Behar KL: Adiabatic RARE imaging. NMR Biomed. 2003 Feb. PMID: 12577295

Hyder F, Kida I, Behar KL, Kennan RP, Rothman DL: Dominant events that modulate mass transfer coefficient of oxygen in cerebral cortex. Adv Exp Med Biol. 2003. PMID: 14562735

Hyder F, Brown P, Nixon TW, Behar KL: Mapping cerebral glutamate 13C turnover and oxygen consumption by in vivo NMR. Adv Exp Med Biol. 2003. PMID: 14562702

Novotny EJ Jr, Fulbright RK, Pearl PL, Gibson KM, Rothman DL: Magnetic resonance spectroscopy of neurotransmitters in human brain. Ann Neurol. 2003. PMID: 12891651

Rothman DL, Behar KL, Hyder F, Shulman RG: In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function. Annu Rev Physiol. 2003; 2002 May 1. PMID: 12524459

de Graaf RA, Brown PB, Mason GF, Rothman DL, Behar KL: Detection of [1,6-13C2]-glucose metabolism in rat brain by in vivo 1H-[13C]-NMR spectroscopy. Magn Reson Med. 2003 Jan. PMID: 12509818

Petroff OA, Errante LD, Rothman DL, Kim JH, Spencer DD: Neuronal and glial metabolite content of the epileptogenic human hippocampus. Ann Neurol. 2002 Nov. PMID: 12402262

Epperson CN, Haga K, Mason GF, Sellers E, Gueorguieva R, Zhang W, Weiss E, Rothman DL, Krystal JH: Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study. Arch Gen Psychiatry. 2002 Sep. PMID: 12215085

Kida I, Xu F, Shulman RG, Hyder F: Mapping at glomerular resolution: fMRI of rat olfactory bulb. Magn Reson Med. 2002 Sep. PMID: 12210928

Hyder F, Rothman DL, Shulman RG: Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI. Proc Natl Acad Sci U S A. 2002 Aug 6; 2002 Jul 19. PMID: 12134057

Smith AJ, Blumenfeld H, Behar KL, Rothman DL, Shulman RG, Hyder F: Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI. Proc Natl Acad Sci U S A. 2002 Aug 6; 2002 Jul 19. PMID: 12134056

Shulman RG, Hyder F, Rothman DL: Biophysical basis of brain activity: implications for neuroimaging. Q Rev Biophys. 2002 Aug. PMID: 12599751

Roa DE, Song H, Yue N, D'Errico F, Nath R: Measured TG-60 dosimetric parameters of the Novoste Beta-Cath 90Sr/Y source trains for intravascular brachytherapy. Cardiovasc Radiat Med. 2002 Jul-Dec. PMID: 12974374

Petroff OA, Errante LD, Rothman DL, Kim JH, Spencer DD: Glutamate-glutamine cycling in the epileptic human hippocampus. Epilepsia. 2002 Jul. PMID: 12102672

Mason GF, Rothman DL: Graded image segmentation of brain tissue in the presence of inhomogeneous radio frequency fields. Magn Reson Imaging. 2002 Jun. PMID: 12206869

Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, Cline GW, DePaoli AM, Taylor SI, Gorden P, Shulman GI: Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest. 2002 May. PMID: 12021250

Sanacora G, Mason GF, Rothman DL, Krystal JH: Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors. Am J Psychiatry. 2002 Apr. PMID: 11925309

Sinha R, Dufour S, Petersen KF, LeBon V, Enoksson S, Ma YZ, Savoye M, Rothman DL, Shulman GI, Caprio S: Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity. Diabetes. 2002 Apr. PMID: 11916921

Kennan RP, Behar KL: Continuous-wave near-infrared spectroscopy using pathlength-independent hypoxia normalization. J Biomed Opt. 2002 Apr. PMID: 11966308

Mayerson AB, Hundal RS, Dufour S, Lebon V, Befroy D, Cline GW, Enocksson S, Inzucchi SE, Shulman GI, Petersen KF: The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes. 2002 Mar. PMID: 11872682

Lebon V, Petersen KF, Cline GW, Shen J, Mason GF, Dufour S, Behar KL, Shulman GI, Rothman DL: Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. J Neurosci. 2002 Mar 1. PMID: 11880482

Chen Q, Ma E, Behar KL, Xu T, Haddad GG: Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. J Biol Chem. 2002 Feb 1; 2001 Nov 21. PMID: 11719513

Patel AB, Rothman DL, Cline GW, Behar KL: Glutamine is the major precursor for GABA synthesis in rat neocortex in vivo following acute GABA-transaminase inhibition. Brain Res. 2001 Nov 23. PMID: 11701133

Hyder F, Kida I, Behar KL, Kennan RP, Maciejewski PK, Rothman DL: Quantitative functional imaging of the brain: towards mapping neuronal activity by BOLD fMRI. NMR Biomed. 2001 Nov-Dec. PMID: 11746934

Shulman RG, Hyder F, Rothman DL: Lactate efflux and the neuroenergetic basis of brain function. NMR Biomed. 2001 Nov-Dec. PMID: 11746930

Mason GF, Martin DL, Martin SB, Manor D, Sibson NR, Patel A, Rothman DL, Behar KL: Decrease in GABA synthesis rate in rat cortex following GABA-transaminase inhibition correlates with the decrease in GAD(67) protein. Brain Res. 2001 Sep 28. PMID: 11578600

Lebon V, Dufour S, Petersen KF, Ren J, Jucker BM, Slezak LA, Cline GW, Rothman DL, Shulman GI: Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle. J Clin Invest. 2001 Sep. PMID: 11544279

de Graaf RA, Rothman DL: Detection of gamma-aminobutyric acid (GABA) by longitudinal scalar order difference editing. J Magn Reson. 2001 Sep. PMID: 11531371

Behar KL, Rothman DL: In vivo nuclear magnetic resonance studies of glutamate-gamma-aminobutyric acid-glutamine cycling in rodent and human cortex: the central role of glutamine. J Nutr. 2001 Sep. PMID: 11533301

Goddard AW, Mason GF, Almai A, Rothman DL, Behar KL, Petroff OA, Charney DS, Krystal JH: Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Arch Gen Psychiatry. 2001 Jun. PMID: 11386984

Shulman RG: Spectroscopic contributions to the understanding of hemoglobin function: implications for structural biology. IUBMB Life. 2001 Jun. PMID: 11758802

Shulman RG, Hyder F, Rothman DL: Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging. Proc Natl Acad Sci U S A. 2001 May 22; 2001 May 8. PMID: 11344262

de Graaf RA, Pan JW, Telang F, Lee JH, Brown P, Novotny EJ, Hetherington HP, Rothman DL: Differentiation of glucose transport in human brain gray and white matter. J Cereb Blood Flow Metab. 2001 May. PMID: 11333358

Petersen KF, Cline GW, Gerard DP, Magnusson I, Rothman DL, Shulman GI: Contribution of net hepatic glycogen synthesis to disposal of an oral glucose load in humans. Metabolism. 2001 May. PMID: 11319724

Chase JR, Rothman DL, Shulman RG: Flux control in the rat gastrocnemius glycogen synthesis pathway by in vivo 13C/31P NMR spectroscopy. Am J Physiol Endocrinol Metab. 2001 Apr. PMID: 11254467

Petroff OA, Hyder F, Rothman DL, Mattson RH: Topiramate rapidly raises brain GABA in epilepsy patients. Epilepsia. 2001 Apr. PMID: 11440351

Rothman DL: Studies of metabolic compartmentation and glucose transport using in vivo MRS. NMR Biomed. 2001 Apr. PMID: 11320540

Petroff OA, Hyder F, Rothman DL, Mattson RH: Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures. Neurology. 2001 Mar 27. PMID: 11274303

Sibson NR, Mason GF, Shen J, Cline GW, Herskovits AZ, Wall JE, Behar KL, Rothman DL, Shulman RG: In vivo (13)C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during. J Neurochem. 2001 Feb. PMID: 11181817

Shulman RG, Rothman DL: The "glycogen shunt" in exercising muscle: A role for glycogen in muscle energetics and fatigue. Proc Natl Acad Sci U S A. 2001 Jan 16. PMID: 11209049

Shulman RG: Functional imaging studies: linking mind and basic neuroscience. Am J Psychiatry. 2001 Jan. PMID: 11136626

Shulman RG, Rothman DL: 13C NMR of intermediary metabolism: implications for systemic physiology. Annu Rev Physiol. 2001. PMID: 11181947

Xu F, Kida I, Hyder F, Shulman RG: Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proc Natl Acad Sci U S A. 2000 Sep 12. PMID: 10973488

Petroff OA, Hyder F, Rothman DL, Mattson RH: Effects of gabapentin on brain GABA, homocarnosine, and pyrrolidinone in epilepsy patients. Epilepsia. 2000 Jun. PMID: 10840398

Kida I, Kennan RP, Rothman DL, Behar KL, Hyder F: High-resolution CMR(O2) mapping in rat cortex: a multiparametric approach to calibration of BOLD image contrast at 7 Tesla. J Cereb Blood Flow Metab. 2000 May. PMID: 10826536

Hyder F, Renken R, Kennan RP, Rothman DL: Quantitative multi-modal functional MRI with blood oxygenation level dependent exponential decays adjusted for flow attenuated inversion recovery (BOLDED AFFAIR). Magn Reson Imaging. 2000 Apr. PMID: 10745130

Price TB, Laurent D, Petersen KF, Rothman DL, Shulman GI: Glycogen loading alters muscle glycogen resynthesis after exercise. J Appl Physiol (1985). 2000 Feb. PMID: 10658040

Krssak M, Petersen KF, Bergeron R, Price T, Laurent D, Rothman DL, Roden M, Shulman GI: Intramuscular glycogen and intramyocellular lipid utilization during prolonged exercise and recovery in man: a 13C and 1H nuclear magnetic resonance spectroscopy study. J Clin Endocrinol Metab. 2000 Feb. PMID: 10690886

Petroff OA, Mattson RH, Rothman DL: Proton MRS: GABA and glutamate. Adv Neurol. 2000. PMID: 10999208

Hyder F, Renken R, Rothman DL: In vivo carbon-edited detection with proton echo-planar spectroscopic imaging (ICED PEPSI): [3,4-(13)CH(2)]glutamate/glutamine tomography in rat brain. Magn Reson Med. 1999 Dec. PMID: 10571918

Sanacora G, Mason GF, Rothman DL, Behar KL, Hyder F, Petroff OA, Berman RM, Charney DS, Krystal JH: Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Arch Gen Psychiatry. 1999 Nov. PMID: 10565505

Price TB, Rothman DL, Shulman RG: NMR of glycogen in exercise. Proc Nutr Soc. 1999 Nov. PMID: 10817152

Verhoeff NP, Petroff OA, Hyder F, Zoghbi SS, Fujita M, Rajeevan N, Rothman DL, Seibyl JP, Mattson RH, Innis RB: Effects of vigabatrin on the GABAergic system as determined by [123I]iomazenil SPECT and GABA MRS. Epilepsia. 1999 Oct. PMID: 10528940

Rothman DL, Sibson NR, Hyder F, Shen J, Behar KL, Shulman RG: In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics. Philos Trans R Soc Lond B Biol Sci. 1999 Jul 29. PMID: 10466144

Cline GW, Petersen KF, Krssak M, Shen J, Hundal RS, Trajanoski Z, Inzucchi S, Dresner A, Rothman DL, Shulman GI: Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes. N Engl J Med. 1999 Jul 22. PMID: 10413736

Petroff OA, Hyder F, Collins T, Mattson RH, Rothman DL: Acute effects of vigabatrin on brain GABA and homocarnosine in patients with complex partial seizures. Epilepsia. 1999 Jul. PMID: 10403220

Behar KL, Rothman DL, Petersen KF, Hooten M, Delaney R, Petroff OA, Shulman GI, Navarro V, Petrakis IL, Charney DS, Krystal JH: Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. Am J Psychiatry. 1999 Jun. PMID: 10360140

Hyder F, Petroff OA, Mattson RH, Rothman DL: Localized 1H NMR measurements of 2-pyrrolidinone in human brain in vivo. Magn Reson Med. 1999 May. PMID: 10332870

Novotny EJ Jr, Hyder F, Shevell M, Rothman DL: GABA changes with vigabatrin in the developing human brain. Epilepsia. 1999 Apr. PMID: 10219272

Petroff OA, Rothman DL, Behar KL, Hyder F, Mattson RH: Effects of valproate and other antiepileptic drugs on brain glutamate, glutamine, and GABA in patients with refractory complex partial seizures. Seizure. 1999 Apr. PMID: 10222306

Shulman RG, Rothman DL, Hyder F: Stimulated changes in localized cerebral energy consumption under anesthesia. Proc Natl Acad Sci U S A. 1999 Mar 16. PMID: 10077669

Petroff OA, Hyder F, Mattson RH, Rothman DL: Topiramate increases brain GABA, homocarnosine, and pyrrolidinone in patients with epilepsy. Neurology. 1999 Feb. PMID: 10025774

Hyder F, Shulman RG, Rothman DL: Regulation of cerebral oxygen delivery. Adv Exp Med Biol. 1999. PMID: 10659136

Petroff OA, Behar KL, Rothman DL: New NMR measurements in epilepsy. Measuring brain GABA in patients with complex partial seizures. Adv Neurol. 1999. PMID: 10514877

Krssak M, Falk Petersen K, Dresner A, DiPietro L, Vogel SM, Rothman DL, Roden M, Shulman GI: Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study. Diabetologia. 1999 Jan. PMID: 10027589

Dresner A, Laurent D, Marcucci M, Griffin ME, Dufour S, Cline GW, Slezak LA, Andersen DK, Hundal RS, Rothman DL, Petersen KF, Shulman GI: Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J Clin Invest. 1999 Jan. PMID: 9916137

Shen J, Shungu DC, Rothman DL: In vivo chemical shift imaging of gamma-aminobutyric acid in the human brain. Magn Reson Med. 1999 Jan. PMID: 10025609

Petroff OA, Mattson RH, Behar KL, Hyder F, Rothman DL: Vigabatrin increases human brain homocarnosine and improves seizure control. Ann Neurol. 1998 Dec. PMID: 9851440

Shen J, Novotny EJ, Rothman DL: In vivo lactate and beta-hydroxybutyrate editing using a pure-phase refocusing pulse train. Magn Reson Med. 1998 Nov. PMID: 9797163

Shulman RG, Rothman DL: Interpreting functional imaging studies in terms of neurotransmitter cycling. Proc Natl Acad Sci U S A. 1998 Sep 29. PMID: 9751778

Hyder F, Shulman RG, Rothman DL: A model for the regulation of cerebral oxygen delivery. J Appl Physiol (1985). 1998 Aug. PMID: 9688733

Yang X, Renken R, Hyder F, Siddeek M, Greer CA, Shepherd GM, Shulman RG: Dynamic mapping at the laminar level of odor-elicited responses in rat olfactory bulb by functional MRI. Proc Natl Acad Sci U S A. 1998 Jun 23. PMID: 9636216

Jucker BM, Lee JY, Shulman RG: In vivo 13C NMR measurements of hepatocellular tricarboxylic acid cycle flux. J Biol Chem. 1998 May 15. PMID: 9575166

Petersen KF, Laurent D, Rothman DL, Cline GW, Shulman GI: Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans. J Clin Invest. 1998 Mar 15. PMID: 9502760

Petersen KF, Hendler R, Price T, Perseghin G, Rothman DL, Held N, Amatruda JM, Shulman GI: 13C/31P NMR studies on the mechanism of insulin resistance in obesity. Diabetes. 1998 Mar. PMID: 9519743

Shulman RG: Hard days in the trenches. FASEB J. 1998 Mar. PMID: 9506465

Petroff OA, Rothman DL: Measuring human brain GABA in vivo: effects of GABA-transaminase inhibition with vigabatrin. Mol Neurobiol. 1998 Feb. PMID: 9554704

Sibson NR, Dhankhar A, Mason GF, Rothman DL, Behar KL, Shulman RG: Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity. Proc Natl Acad Sci U S A. 1998 Jan 6. PMID: 9419373

Shen J, Sibson NR, Cline G, Behar KL, Rothman DL, Shulman RG: 15N-NMR spectroscopy studies of ammonia transport and glutamine synthesis in the hyperammonemic rat brain. Dev Neurosci. 1998. PMID: 9778582

Sibson NR, Shen J, Mason GF, Rothman DL, Behar KL, Shulman RG: Functional energy metabolism: in vivo 13C-NMR spectroscopy evidence for coupling of cerebral glucose consumption and glutamatergic neuronalactivity. Dev Neurosci. 1998. PMID: 9778568

Rothman DL, Behar KL, Prichard JW, Petroff OA: Homocarnosine and the measurement of neuronal pH in patients with epilepsy. Magn Reson Med. 1997 Dec. PMID: 9402193

Yang X, Hyder F, Shulman RG: Functional MRI BOLD signal coincides with electrical activity in the rat whisker barrels. Magn Reson Med. 1997 Dec. PMID: 9402186

Shen J, Rycyna RE, Rothman DL: Improvements on an in vivo automatic shimming method [FASTERMAP]. Magn Reson Med. 1997 Nov. PMID: 9358459

Hyder F, Rothman DL, Mason GF, Rangarajan A, Behar KL, Shulman RG: Oxidative glucose metabolism in rat brain during single forepaw stimulation: a spatially localized 1H[13C] nuclear magnetic resonance study. J Cereb Blood Flow Metab. 1997 Oct. PMID: 9346428

Shen J, Rothman DL: Fast automatic adjustment of on-axis shims for high-resolution NMR. J Magn Reson. 1997 Aug. PMID: 9281488

Hyder F, Phelps EA, Wiggins CJ, Labar KS, Blamire AM, Shulman RG: "Willed action": a functional MRI study of the human prefrontal cortex during a sensorimotor task. Proc Natl Acad Sci U S A. 1997 Jun 24. PMID: 9192679

Cline GW, Magnusson I, Rothman DL, Petersen KF, Laurent D, Shulman GI: Mechanism of impaired insulin-stimulated muscle glucose metabolism in subjects with insulin-dependent diabetes mellitus. J Clin Invest. 1997 May 1. PMID: 9151794

Sibson NR, Dhankhar A, Mason GF, Behar KL, Rothman DL, Shulman RG: In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling. Proc Natl Acad Sci U S A. 1997 Mar 18. PMID: 9122259

Phelps EA, Hyder F, Blamire AM, Shulman RG: FMRI of the prefrontal cortex during overt verbal fluency. Neuroreport. 1997 Jan 20. PMID: 9080448

Shen J, Rothman DL: Adiabatic slice-selective excitation for surface coils. J Magn Reson. 1997 Jan. PMID: 9169211

Dhankhar A, Wexler BE, Fulbright RK, Halwes T, Blamire AM, Shulman RG: Functional magnetic resonance imaging assessment of the human brain auditory cortex response to increasing word presentation rates. J Neurophysiol. 1997 Jan. PMID: 9120588

Petroff OA, Rothman DL, Behar KL, Mattson RH: Low brain GABA level is associated with poor seizure control. Ann Neurol. 1996 Dec. PMID: 9007096

Petroff OA, Behar KL, Mattson RH, Rothman DL: Human brain gamma-aminobutyric acid levels and seizure control following initiation of vigabatrin therapy. J Neurochem. 1996 Dec. PMID: 8931472

Petroff OA, Rothman DL, Behar KL, Collins TL, Mattson RH: Human brain GABA levels rise rapidly after initiation of vigabatrin therapy. Neurology. 1996 Dec. PMID: 8960747

Perseghin G, Price TB, Petersen KF, Roden M, Cline GW, Gerow K, Rothman DL, Shulman GI: Increased glucose transport-phosphorylation and muscle glycogen synthesis after exercise training in insulin-resistant subjects. N Engl J Med. 1996 Oct 31. PMID: 8857019

Shulman RG: Nuclear magnetic resonance studies of glucose metabolism in non-insulin-dependent diabetes mellitus subjects. Mol Med. 1996 Sep. PMID: 8898370

Manor D, Rothman DL, Mason GF, Hyder F, Petroff OA, Behar KL: The rate of turnover of cortical GABA from [1-13C]glucose is reduced in rats treated with the GABA-transaminase inhibitor vigabatrin (gamma-vinyl GABA). Neurochem Res. 1996 Sep. PMID: 8897466

Hyder F, Chase JR, Behar KL, Mason GF, Siddeek M, Rothman DL, Shulman RG: Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR. Proc Natl Acad Sci U S A. 1996 Jul 23. PMID: 8755523

Shulman RG, Rothman DL: Enzymatic phosphorylation of muscle glycogen synthase: a mechanism for maintenance of metabolic homeostasis. Proc Natl Acad Sci U S A. 1996 Jul 23. PMID: 8755501

Petersen KF, West AB, Reuben A, Rothman DL, Shulman GI: Noninvasive assessment of hepatic triglyceride content in humans with 13C nuclear magnetic resonance spectroscopy. Hepatology. 1996 Jul. PMID: 8707248

Blamire AM, Rothman DL, Nixon T: Dynamic shim updating: a new approach towards optimized whole brain shimming. Magn Reson Med. 1996 Jul. PMID: 8795035

Roden M, Price TB, Perseghin G, Petersen KF, Rothman DL, Cline GW, Shulman GI: Mechanism of free fatty acid-induced insulin resistance in humans. J Clin Invest. 1996 Jun 15. PMID: 8675698

Price TB, Perseghin G, Duleba A, Chen W, Chase J, Rothman DL, Shulman RG, Shulman GI: NMR studies of muscle glycogen synthesis in insulin-resistant offspring of parents with non-insulin-dependent diabetes mellitus immediately after glycogen-depleting exercise. Proc Natl Acad Sci U S A. 1996 May 28. PMID: 8643574

Gruetter R, Novotny EJ, Boulware SD, Rothman DL, Shulman RG: 1H NMR studies of glucose transport in the human brain. J Cereb Blood Flow Metab. 1996 May. PMID: 8621747

Hwang JH, Graham GD, Behar KL, Alger JR, Prichard JW, Rothman DL: Short echo time proton magnetic resonance spectroscopic imaging of macromolecule and metabolite signal intensities in the human brain. Magn Reson Med. 1996 May. PMID: 8722812

Petroff OA, Rothman DL, Behar KL, Mattson RH: Human brain GABA levels rise after initiation of vigabatrin therapy but fail to rise further with increasing dose. Neurology. 1996 May. PMID: 8628502

Roden M, Perseghin G, Petersen KF, Hwang JH, Cline GW, Gerow K, Rothman DL, Shulman GI: The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans. J Clin Invest. 1996 Feb 1. PMID: 8609218

Yang X, Hyder F, Shulman RG: Activation of single whisker barrel in rat brain localized by functional magnetic resonance imaging. Proc Natl Acad Sci U S A. 1996 Jan 9. PMID: 8552664

Petersen KF, Price T, Cline GW, Rothman DL, Shulman GI: Contribution of net hepatic glycogenolysis to glucose production during the early postprandial period. Am J Physiol. 1996 Jan. PMID: 8772491

Petroff OA, Rothman DL, Behar KL, Lamoureux D, Mattson RH: The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy. Ann Neurol. 1996 Jan. PMID: 8572673

Shulman RG, Rothman DL, Price TB: Nuclear magnetic resonance studies of muscle and applications to exercise and diabetes. Diabetes. 1996 Jan. PMID: 8529808

Taylor R, Magnusson I, Rothman DL, Cline GW, Caumo A, Cobelli C, Shulman GI: Direct assessment of liver glycogen storage by 13C nuclear magnetic resonance spectroscopy and regulation of glucose homeostasis after a mixed meal in normal subjects. J Clin Invest. 1996 Jan 1. PMID: 8550823

Shulman RG, Bloch G, Rothman DL: In vivo regulation of muscle glycogen synthase and the control of glycogen synthesis. Proc Natl Acad Sci U S A. 1995 Sep 12. PMID: 7567971

Petroff OA, Rothman DL, Behar KL, Mattson RH: Initial observations on effect of vigabatrin on in vivo 1H spectroscopic measurements of gamma-aminobutyric acid, glutamate, and glutamine in human brain. Epilepsia. 1995 May. PMID: 7614922

Rothman DL, Magnusson I, Cline G, Gerard D, Kahn CR, Shulman RG, Shulman GI: Decreased muscle glucose transport/phosphorylation is an early defect in the pathogenesis of non-insulin-dependent diabetes mellitus. Proc Natl Acad Sci U S A. 1995 Feb 14. PMID: 7862678

Magnusson I, Rothman DL, Gerard DP, Katz LD, Shulman GI: Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration. Diabetes. 1995 Feb. PMID: 7859939

Hwang JH, Perseghin G, Rothman DL, Cline GW, Magnusson I, Petersen KF, Shulman GI: Impaired net hepatic glycogen synthesis in insulin-dependent diabetic subjects during mixed meal ingestion. A 13C nuclear magnetic resonance spectroscopy study. J Clin Invest. 1995 Feb. PMID: 7860761

Novotny EJ Jr, Avison MJ, Herschkowitz N, Petroff OA, Prichard JW, Seashore MR, Rothman DL: In vivo measurement of phenylalanine in human brain by proton nuclear magnetic resonance spectroscopy. Pediatr Res. 1995 Feb. PMID: 7731764

Mason GF, Gruetter R, Rothman DL, Behar KL, Shulman RG, Novotny EJ: Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR. J Cereb Blood Flow Metab. 1995 Jan. PMID: 7798329

Hyder F, Rothman DL, Blamire AM: Image reconstruction of sequentially sampled echo-planar data. Magn Reson Imaging. 1995. PMID: 7898286

Jucker BM, Barnard ML, Shulman RG: NMR investigation of the futile cycling of ethanol in chronic alcoholic rats. Alcohol Clin Exp Res. 1994 Dec. PMID: 7695033

Cline GW, Rothman DL, Magnusson I, Katz LD, Shulman GI: 13C-nuclear magnetic resonance spectroscopy studies of hepatic glucose metabolism in normal subjects and subjects with insulin-dependent diabetes mellitus. J Clin Invest. 1994 Dec. PMID: 7989593

Shulman RG, Rothman DL, Blamire AM: NMR studies of human brain function. Trends Biochem Sci. 1994 Dec. PMID: 7846759

Gruetter R, Novotny EJ, Boulware SD, Mason GF, Rothman DL, Shulman GI, Prichard JW, Shulman RG: Localized 13C NMR spectroscopy in the human brain of amino acid labeling from D-[1-13C]glucose. J Neurochem. 1994 Oct. PMID: 7931289

Behar KL, Rothman DL, Spencer DD, Petroff OA: Analysis of macromolecule resonances in 1H NMR spectra of human brain. Magn Reson Med. 1994 Sep. PMID: 7984061

Price TB, Taylor R, Mason GF, Rothman DL, Shulman GI, Shulman RG: Turnover of human muscle glycogen with low-intensity exercise. Med Sci Sports Exerc. 1994 Aug. PMID: 7968433

Hyder F, Behar KL, Martin MA, Blamire AM, Shulman RG: Dynamic magnetic resonance imaging of the rat brain during forepaw stimulation. J Cereb Blood Flow Metab. 1994 Jul. PMID: 8014212

Gruetter R, Magnusson I, Rothman DL, Avison MJ, Shulman RG, Shulman GI: Validation of 13C NMR measurements of liver glycogen in vivo. Magn Reson Med. 1994 Jun. PMID: 8057810

Magnusson I, Rothman DL, Jucker B, Cline GW, Shulman RG, Shulman GI: Liver glycogen turnover in fed and fasted humans. Am J Physiol. 1994 May. PMID: 8203517

Chen W, Avison MJ, Bloch G, Shulman RG: Proton NMR observation of glycogen in vivo. Magn Reson Med. 1994 May. PMID: 8015415

Bloch G, Chase JR, Meyer DB, Avison MJ, Shulman GI, Shulman RG: In vivo regulation of rat muscle glycogen resynthesis after intense exercise. Am J Physiol. 1994 Jan. PMID: 8304447

Price TB, Rothman DL, Taylor R, Avison MJ, Shulman GI, Shulman RG: Human muscle glycogen resynthesis after exercise: insulin-dependent and -independent phases. J Appl Physiol (1985). 1994 Jan. PMID: 7909795

Blamire AM, Shulman RG: Implementation of echo-planar imaging on an unmodified spectrometer at 2.1 Tesla for functional imaging. Magn Reson Imaging. 1994. PMID: 8057772

Blamire AM, Graham GD, Rothman DL, Prichard JW: Proton spectroscopy of human stroke: assessment of transverse relaxation times and partial volume effects in single volume steam MRS. Magn Reson Imaging. 1994. PMID: 7854028

Graham GD, Blamire AM, Rothman DL, Brass LM, Fayad PB, Petroff OA, Prichard JW: Early temporal variation of cerebral metabolites after human stroke. A proton magnetic resonance spectroscopy study. Stroke. 1993 Dec. PMID: 8248973

Chen W, Avison MJ, Zhu XH, Shulman RG: NMR studies of 1H NOEs in glycogen. Biochemistry. 1993 Nov 2. PMID: 8218214

Chen W, Novotny EJ, Zhu XH, Rothman DL, Shulman RG: Localized 1H NMR measurement of glucose consumption in the human brain during visual stimulation. Proc Natl Acad Sci U S A. 1993 Nov 1. PMID: 8234332

Chen W, Zhu XH, Avison MJ, Shulman RG: Nuclear magnetic resonance relaxation of glycogen H1 in solution. Biochemistry. 1993 Sep 14. PMID: 8369311

Bloch G, Chase JR, Avison MJ, Shulman RG: In vivo 31P NMR measurement of glucose-6-phosphate in the rat muscle after exercise. Magn Reson Med. 1993 Sep. PMID: 8412606

Taylor R, Price TB, Katz LD, Shulman RG, Shulman GI: Direct measurement of change in muscle glycogen concentration after a mixed meal in normal subjects. Am J Physiol. 1993 Aug. PMID: 8368292

Rothman DL, Petroff OA, Behar KL, Mattson RH: Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo. Proc Natl Acad Sci U S A. 1993 Jun 15. PMID: 8516315

McCarthy G, Blamire AM, Rothman DL, Gruetter R, Shulman RG: Echo-planar magnetic resonance imaging studies of frontal cortex activation during word generation in humans. Proc Natl Acad Sci U S A. 1993 Jun 1. PMID: 8506340

Shulman RG, Blamire AM, Rothman DL, McCarthy G: Nuclear magnetic resonance imaging and spectroscopy of human brain function. Proc Natl Acad Sci U S A. 1993 Apr 15. PMID: 8475050

Behar KL, Fitzpatrick SM, Hetherington HP, Shulman RG: Cerebral metabolic studies in vivo by combined 1H/31P and 1H/13C NMR spectroscopic methods. Acta Neurochir Suppl (Wien). 1993. PMID: 8421959

Gruetter R, Novotny EJ, Boulware SD, Rothman DL, Mason GF, Shulman GI, Tamborlane WV, Shulman RG: Non-invasive measurements of the cerebral steady-state glucose concentration and transport in humans by 13C nuclear magnetic resonance. Adv Exp Med Biol. 1993. PMID: 8333347

Mason GF, Behar KL, Martin MA, Shulman RG: Rat brain glucose concentration and transport kinetics determined with 13C nuclear magnetic resonance spectroscopy. Adv Exp Med Biol. 1993. PMID: 8333345

Blamire AM, Ogawa S, Ugurbil K, Rothman D, McCarthy G, Ellermann JM, Hyder F, Rattner Z, Shulman RG: Dynamic mapping of the human visual cortex by high-speed magnetic resonance imaging. Proc Natl Acad Sci U S A. 1992 Nov 15. PMID: 1438317

Petroff OA, Novotny EJ, Avison M, Rothman DL, Alger JR, Ogino T, Shulman GI, Prichard JW: Cerebral lactate turnover after electroshock: in vivo measurements by 1H/13C magnetic resonance spectroscopy. J Cereb Blood Flow Metab. 1992 Nov. PMID: 1400641

Rothman DL, Novotny EJ, Shulman GI, Howseman AM, Petroff OA, Mason G, Nixon T, Hanstock CC, Prichard JW, Shulman RG: 1H-[13C] NMR measurements of [4-13C]glutamate turnover in human brain. Proc Natl Acad Sci U S A. 1992 Oct 15. PMID: 1409672

Magnusson I, Rothman DL, Katz LD, Shulman RG, Shulman GI: Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. J Clin Invest. 1992 Oct. PMID: 1401068

Gruetter R, Rothman DL, Novotny EJ, Shulman GI, Prichard JW, Shulman RG: Detection and assignment of the glucose signal in 1H NMR difference spectra of the human brain. Magn Reson Med. 1992 Sep. PMID: 1435204

Taylor R, Price TB, Rothman DL, Shulman RG, Shulman GI: Validation of 13C NMR measurement of human skeletal muscle glycogen by direct biochemical assay of needle biopsy samples. Magn Reson Med. 1992 Sep. PMID: 1435198

Shachar-Hill Y, Shulman RG: Co2+ as a shift reagent for 35Cl NMR of chloride with vesicles and cells. Biochemistry. 1992 Jul 14. PMID: 1627566

Petroff OA, Graham GD, Blamire AM, al-Rayess M, Rothman DL, Fayad PB, Brass LM, Shulman RG, Prichard JW: Spectroscopic imaging of stroke in humans: histopathology correlates of spectral changes. Neurology. 1992 Jul. PMID: 1620345

Van Waarde A, Avison MJ, Thulin G, Gaudio KM, Shulman RG, Siegel NJ: Role of nucleoside uptake in renal postischemic ATP synthesis. Am J Physiol. 1992 Jun. PMID: 1621813

Mason GF, Behar KL, Rothman DL, Shulman RG: NMR determination of intracerebral glucose concentration and transport kinetics in rat brain. J Cereb Blood Flow Metab. 1992 May. PMID: 1569138

Mason GF, Rothman DL, Behar KL, Shulman RG: NMR determination of the TCA cycle rate and alpha-ketoglutarate/glutamate exchange rate in rat brain. J Cereb Blood Flow Metab. 1992 May. PMID: 1349022

Gruetter R, Rothman DL, Novotny EJ, Shulman RG: Localized 13C NMR spectroscopy of myo-inositol in the human brain in vivo. Magn Reson Med. 1992 May. PMID: 1593953

Rothman DL, Hanstock CC, Petroff OA, Novotny EJ, Prichard JW, Shulman RG: Localized 1H NMR spectra of glutamate in the human brain. Magn Reson Med. 1992 May. PMID: 1350656

Rothman DL, Shulman RG, Shulman GI: 31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus. J Clin Invest. 1992 Apr. PMID: 1556176

Graham GD, Blamire AM, Howseman AM, Rothman DL, Fayad PB, Brass LM, Petroff OA, Shulman RG, Prichard JW: Proton magnetic resonance spectroscopy of cerebral lactate and other metabolites in stroke patients. Stroke. 1992 Mar. PMID: 1542892

Gruetter R, Novotny EJ, Boulware SD, Rothman DL, Mason GF, Shulman GI, Shulman RG, Tamborlane WV: Direct measurement of brain glucose concentrations in humans by 13C NMR spectroscopy. Proc Natl Acad Sci U S A. 1992 Feb 1. PMID: 1736294

Zang LH, Howseman AM, Shulman RG: Assignment of the 1H chemical shifts of glycogen. Carbohydr Res. 1991 Nov 11. PMID: 1667378

Rothman DL, Shulman RG, Shulman GI: N.m.r. studies of muscle glycogen synthesis in normal and non-insulin-dependent diabetic subjects. Biochem Soc Trans. 1991 Nov. PMID: 1794599

Rothman DL, Magnusson I, Katz LD, Shulman RG, Shulman GI: Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR. Science. 1991 Oct 25. PMID: 1948033

Rothman DL, Howseman AM, Graham GD, Petroff OA, Lantos G, Fayad PB, Brass LM, Shulman GI, Shulman RG, Prichard JW: Localized proton NMR observation of [3-13C]lactate in stroke after [1-13C]glucose infusion. Magn Reson Med. 1991 Oct. PMID: 1745129

Shulman RG: Is channeling a disproveable hypothesis? J Theor Biol. 1991 Sep 7. PMID: 1753757

Gruetter R, Prolla TA, Shulman RG: 13C NMR visibility of rabbit muscle glycogen in vivo. Magn Reson Med. 1991 Aug. PMID: 1775059

Avison MJ, Rothman DL, Nixon TW, Long WS, Siegel NJ: 1H NMR study of renal trimethylamine responses to dehydration and acute volume loading in man. Proc Natl Acad Sci U S A. 1991 Jul 15. PMID: 2068084

Pan JW, Hamm JR, Hetherington HP, Rothman DL, Shulman RG: Correlation of lactate and pH in human skeletal muscle after exercise by 1H NMR. Magn Reson Med. 1991 Jul. PMID: 1943662

Pan JW, Hetherington HP, Hamm JR, Shulman RG: Quantitation of metabolites by 1H NMR. Magn Reson Med. 1991 Jul. PMID: 1943661

Price TB, Rothman DL, Avison MJ, Buonamico P, Shulman RG: 13C-NMR measurements of muscle glycogen during low-intensity exercise. J Appl Physiol (1985). 1991 Apr. PMID: 2055862

Shulman RG, Rothman DL, Behar KL, Prichard JW: High resolution NMR studies of cerebral glucose metabolism in rats and humans. Adv Exp Med Biol. 1991. PMID: 1927690

Novotny EJ Jr, Ogino T, Rothman DL, Petroff OA, Prichard JW, Shulman RG: Direct carbon versus proton heteronuclear editing of 2-13C ethanol in rabbit brain in vivo: a sensitivity comparison. Magn Reson Med. 1990 Dec. PMID: 2077334

David M, Petit WA, Laughlin MR, Shulman RG, King JE, Barrett EJ: Simultaneous synthesis and degradation of rat liver glycogen. An in vivo nuclear magnetic resonance spectroscopic study. J Clin Invest. 1990 Aug. PMID: 2117024

Zang LH, Laughlin MR, Rothman DL, Shulman RG: 13C NMR relaxation times of hepatic glycogen in vitro and in vivo. Biochemistry. 1990 Jul 24. PMID: 2397215

Avison MJ, Herschkowitz N, Novotny EJ, Petroff OA, Rothman DL, Colombo JP, Bachmann C, Shulman RG, Prichard JW: Proton NMR observation of phenylalanine and an aromatic metabolite in the rabbit brain in vivo. Pediatr Res. 1990 Jun. PMID: 2162514

Fitzpatrick SM, Hetherington HP, Behar KL, Shulman RG: The flux from glucose to glutamate in the rat brain in vivo as determined by 1H-observed, 13C-edited NMR spectroscopy. J Cereb Blood Flow Metab. 1990 Mar. PMID: 1968068

Zang LH, Rothman DL, Shulman RG: 1H NMR visibility of mammalian glycogen in solution. Proc Natl Acad Sci U S A. 1990 Mar. PMID: 2308928

Shulman GI, Rothman DL, Jue T, Stein P, DeFronzo RA, Shulman RG: Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. N Engl J Med. 1990 Jan 25. PMID: 2403659

Laughlin MR, Petit WA Jr, Shulman RG, Barrett EJ: Measurement of myocardial glycogen synthesis in diabetic and fasted rats. Am J Physiol. 1990 Jan. PMID: 2405698

Pan JW, Shulman RG: In vivo human localized 1H spectroscopy. Magn Reson Med. 1989 Nov. PMID: 2559289

Behar KL, Rothman DL, Hossmann KA: NMR spectroscopic investigation of the recovery of energy and acid-base homeostasis in the cat brain after prolonged ischemia. J Cereb Blood Flow Metab. 1989 Oct. PMID: 2777935

Rossetti L, Rothman DL, DeFronzo RA, Shulman GI: Effect of dietary protein on in vivo insulin action and liver glycogen repletion. Am J Physiol. 1989 Aug. PMID: 2669515

Jue T, Rothman DL, Shulman GI, Tavitian BA, DeFronzo RA, Shulman RG: Direct observation of glycogen synthesis in human muscle with 13C NMR. Proc Natl Acad Sci U S A. 1989 Jun. PMID: 2734301

Fitzpatrick SM, Hetherington HP, Behar KL, Shulman RG: Effects of acute hyperammonemia on cerebral amino acid metabolism and pHi in vivo, measured by 1H and 31P nuclear magnetic resonance. J Neurochem. 1989 Mar. PMID: 2563756

Jue T, Rothman DL, Tavitian BA, Shulman RG: Natural-abundance 13C NMR study of glycogen repletion in human liver and muscle. Proc Natl Acad Sci U S A. 1989 Mar. PMID: 2922392

Van Waarde A, Stromski ME, Thulin G, Gaudio KM, Kashgarian M, Shulman RG, Siegel NJ: Protection of the kidney against ischemic injury by inhibition of 5'-nucleotidase. Am J Physiol. 1989 Feb. PMID: 2537026

Stromski ME, van Waarde A, Avison MJ, Thulin G, Gaudio KM, Kashgarian M, Shulman RG, Siegel NJ: Metabolic and functional consequences of inhibiting adenosine deaminase during renal ischemia in rats. J Clin Invest. 1988 Nov. PMID: 3263396

Pan JW, Hamm JR, Rothman DL, Shulman RG: Intracellular pH in human skeletal muscle by 1H NMR. Proc Natl Acad Sci U S A. 1988 Nov. PMID: 3186694

Petroff OA, Prichard JW, Ogino T, Shulman RG: Proton magnetic resonance spectroscopic studies of agonal carbohydrate metabolism in rabbit brain. Neurology. 1988 Oct. PMID: 3419601

Shulman GI, Rothman DL, Chung Y, Rossetti L, Petit WA Jr, Barrett EJ, Shulman RG: 13C NMR studies of glycogen turnover in the perfused rat liver. J Biol Chem. 1988 Apr 15. PMID: 3128534

Avison MJ, Rothman DL, Nadel E, Shulman RG: Detection of human muscle glycogen by natural abundance 13C NMR. Proc Natl Acad Sci U S A. 1988 Mar. PMID: 3422752

Laughlin MR, Petit WA Jr, Dizon JM, Shulman RG, Barrett EJ: NMR measurements of in vivo myocardial glycogen metabolism. J Biol Chem. 1988 Feb 15. PMID: 3123491

Jue T, Rothman DL, Lohman JA, Hughes EW, Hanstock CC, Shulman RG: Surface coil localization of 31P NMR signals from orthotopic human kidney and liver. Proc Natl Acad Sci U S A. 1988 Feb. PMID: 3422493

Campbell-Burk SL, Jones KA, Shulman RG: 31P NMR saturation-transfer measurements in Saccharomyces cerevisiae: characterization of phosphate exchange reactions by iodoacetate and antimycin A inhibition. Biochemistry. 1987 Nov 17. PMID: 3322400

Campbell-Burk SL, den Hollander JA, Alger JR, Shulman RG: 31P NMR saturation-transfer and 13C NMR kinetic studies of glycolytic regulation during anaerobic and aerobic glycolysis. Biochemistry. 1987 Nov 17. PMID: 2962638

Jue T, Lohman JA, Ordidge RJ, Shulman RG: Natural abundance 13C NMR spectrum of glycogen in humans. Magn Reson Med. 1987 Oct. PMID: 3683168

Degani H, Alger JR, Shulman RG, Petroff OA, Prichard JW: 31P magnetization transfer studies of creatine kinase kinetics in living rabbit brain. Magn Reson Med. 1987 Jul. PMID: 3657491

Prichard JW, Petroff OA, Ogino T, Shulman RG: Cerebral lactate elevation by electroshock: a 1H magnetic resonance study. Ann N Y Acad Sci. 1987. PMID: 3439712

Shulman RG: Contributions of 13C and 1H NMR to physiological control. Ann N Y Acad Sci. 1987. PMID: 3439699

Behar KL, Rothman DL, Fitzpatrick SM, Hetherington HP, Shulman RG: Combined 1H and 31P NMR studies of the rat brain in vivo: effects of altered intracellular pH on metabolism. Ann N Y Acad Sci. 1987. PMID: 3125776