Sudhakar Chelikani, PhD

Associate Research Scientist of Diagnostic Radiology

Contact

Address:
Yale University, School of Medicine
Magnetic Resonance Research Center
BML 325, 310 Cedar Street
New Haven, Connecticut 06520-8042
United States

Email: sudhakar.chelikani@yale.edu
Telephone: (203) 785-7294
Fax: (203) 737-4273

Education

PhD, Yale University, 2001

Please click here for Curriculum Vitae

Research Interests

My interests are mainly in the areas of image registration and segmentation. I am currently working on an NIH funded project (PI: James Duncan) on adaptive prostate radiotherapy. Intensity modulated radiotherapy (IMRT) has the capacity to deliver a precisely shaped treatment plan to fit the target organs, but is limited by the lack of a proper image-guidance system. My colleagues and I are developing an integrated registration cum segmentation platform that uses 3DCT and 3DCBCT (Cone Beam CT) images to achieve this goal. Once fully developed, this platform will perform fully automatic nonrigid registration of relevant images while simultaneously segmenting the target organs. My other interests are in tools such as Bayesian analysis, nonlinear optimization methods, and Monte Carlo based simulations.

Selected Publications

1. W. Greene, S. Chelikani, X. Papademetris, L.H. Staib, J.P.S. Knisely and J. Duncan, Tracking Organ Overlap for a Constrained Non-Rigid Registration Algorithm, IEEE International Symposium on Biomedical Imaging (ISBI), France, 2008
2. W. Greene, S. Chelikani, K. Purushothaman, Z. Chen, J.P.S. Knisely, L.H. Staib, X. Papademetris and J. Duncan, A Constrained Non-Rigid Registration Algorithm for use in Prostate Image-Guided Radiotherapy Medical Imaging Computing and Computer Assisted Intervention (MICCAI), New York, 2008
3. M. Rodriguez, J.S. Liow, S. Thada, M. Sibomana, S. Chelikani, T. Mulnix, C.A. Johnson, C. Michel, W.C. Barker and R.E. Carson, Count-Rate Dependent Component-Based Normalization for the HRRT, IEEE Transactions on Nuclear Science, v.54(3), 2007.
4. S. Chelikani, K. Purushothaman, J. Knisely, Z. Chen, R. Nath, R. Bansal and J. Duncan, A gradient feature weighted Minimax algorithm for registration of multiple portal images to 3DCT volumes in prostate radiotherapy, International Journal of Radiation Oncology, Biology & Physics, v.65(2), 2006.
5. S. Chelikani, J.C. Gore and I.G. Zubal, Optimizing Compton camera geometries, Physics in Medicine and Biology, v.49, 2004.
6. K. Purushothaman, S. Chelikani, J. Knisely and J. Duncan, Variability of Tumor Control under Localization Uncertainty in External Beam Radiation Therapy of Prostate Cancer, American Society for Therapeutic Radiology and Oncology (ASTRO), Atlanta, GA, 2004.
7. S. Chelikani, K. Purushothaman and J. Duncan, Support Vector Machine Density Estimator as a Generalized Parzen Windows Estimator for Mutual Information Based Image Registration, Medical Imaging Computing and Computer Assisted Intervention (MICCAI), Montreal, Canada, 2003.
8. S. Chelikani and I.G. Zubal, Design and Optimization of a Compton Camera for Nuclear Medicine Applications, The Compton Workshop, IEEE Nuclear Science Symposium and Medical Imaging Conference, San Diego, CA, 2001.
9. J.J. Crisco, S. Chelikani, R.K. Brown and S. Wolfe, Exercise decreases ligamentous stiffness in the wrist, Journal of Hand Surgery, v.22(1), 1997.
10. S. Chelikani, S. Rodriguez and M. Robinson, Comparison of tablet versus liquid antacids on acidity in the esophagus and the stomach, American Journal of Gasteroenterology, v.90(5), 1995.

For a further list of Chelikani's publications, please see PubMed.