Xing Wang Deng
Daniel C. Eaton Professor of Molecular, Cellular, and Developmental Biology; Daniel C. Eaton Professor of Plant Biology at Yale; Director of Peking-Yale Center for Plant Molecular Genetics & Agrobiotechnology
Plant Biology, Genome and Epigenome, Development mechanism, Hybrid Vigor, Agribiotechnology Light Regulation
Current ProjectsLight regulation of Plant Development, Genomic and Epigenomic Basis of Hybrid Vigor,
The Role of Proteolysis in Plant Development
My research centers in two areas. One is genome-wide analysis of the relationship between epigenetic modifications and chromatin structure/gene expression in rice and Arabidopsis. We have established several genomic platforms to examine the molecular and genomic basis of rice heterosis and genome expression evolution during rice domestication. We also examine genome wide coding potential and functional implications of ncRNA species larger than miRNAs and siRNAs in both rice and Arabidopsis. Another research area is the molecular and biochemical mechanism for light regulated seedling development in Arabidopsis. We have discovered a dozen pleiotropic COP/DET/FUS loci responsible for mediating light control of seedling development. Their encoded proteins constitute three protein machineries involved in targeting photomorphogenesis-promoting factors for degradation by the 26S proteasome, in response to external stimuli. We are applying both molecular/genetic and genomic approaches to further analyze the action mechanism of those novel cellular machineries, which are conserved among all multicellular organisms.