Xing Wang Deng, PhD

Daniel C. Eaton Senior Research Scientist in Molecular, Cellular, and Developmental Biology; Daniel C. Eaton Professor of Plant Biology at Yale; Director of Peking-Yale Center for Plant Molecular Genetics & Agrobiotechnology

Research Interests

Research Summary

My research centers in two areas. One is genome-wide analysis of the relationship between epigenetic modifications and chromatin structure/gene expression in rice and Arabidopsis. We have established several genomic platforms to examine the molecular and genomic basis of rice heterosis and genome expression evolution during rice domestication. We also examine genome wide coding potential and functional implications of ncRNA species larger than miRNAs and siRNAs in both rice and Arabidopsis. Another research area is the molecular and biochemical mechanism for light regulated seedling development in Arabidopsis. We have discovered a dozen pleiotropic COP/DET/FUS loci responsible for mediating light control of seedling development. Their encoded proteins constitute three protein machineries involved in targeting photomorphogenesis-promoting factors for degradation by the 26S proteasome, in response to external stimuli. We are applying both molecular/genetic and genomic approaches to further analyze the action mechanism of those novel cellular machineries, which are conserved among all multicellular organisms.

Extensive Research Description

Light regulation of Plant Development, Genomic and Epigenomic Basis of Hybrid Vigor,
The Role of Proteolysis in Plant Development

Selected Publications

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Contact Info

Xing Wang Deng, PhD
Lab Location
Osborn Memorial Lab
165 Prospect Street, Ste 3rd floor, prospect wing

New Haven, CT 06511
Office Location
Osborn Memorial Lab
165 Prospect Street, Ste OML 352

New Haven, CT 06511
Mailing Address
OML 352165 prospect street
Yale University

New Haven, CT 06520-8104

Deng Lab