Public Health Interests
We study mechanisms that drive organelle structure, identity, and dynamics. Specific areas of interest include how lipid metabolism is coupled to endoplasmic reticulum and nuclear envelope structure, the role of nuclear lamins in nuclear dynamics during cell division and development, and defining functions for inner nuclear membrane proteins in the organization of single cells and complex tissues.
- Bahmanyar S, Biggs R, Schuh AL, Desai A, Muller-Reichert T, Audhya A, Dixon JE, and Oegema K. (2014) Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev. 28(2):121-126
- Han S*, Bahmanyar S*, Zhang P, Grishin N, Oegema K, Crooke R, Graham M, Reue K, Dixon JE, and Goodman JM. (2011) Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pa
- Bahmanyar S*, Kaplan DD*, DeLuca JG, Giddings Jr. TH, O’Toole ET, Winey M, Salmon ED, Casey PJ, Nelson WJ, Barth AI. (2008) ß-Catenin is a Nek2 substrate involved in centrosome separation. Genes Dev. 22(1):91-105.
- Bahmanyar S, Guiney EL, Hatch, EM, Nelson WJ, Barth AI. (2010) Formation of extra centrosomal structures is dependent on ß-catenin. J Cell Sci. 123(Pt 18):3125-35.
- Louie RK*, Bahmanyar S*, Siemers KA*, Votin V, Chang P, Stearns T, Nelson WJ, Barth AIM. (2004) Adenomatous polyposis coli and EB1 localize in close proximity of the mother centriole and EB1 is a functional component of centrosomes. J Cell Sci. 117(Pt 7):