Shawn Michael Ferguson PhD

Assistant Professor of Cell Biology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural BiologyCell Biology: Ferguson Lab

Research Interests

Neurodegenerative Disease; Lysosomes; Alzheimer's Disease; Frontotemporal Dementia; Lysosome Storage Disorders; Neuronal Ceroid Lipofuscinosis more...


  • B.S., University of Ottawa, 1997
  • M.S., University of Ottawa, 1999
  • Ph.D., Vanderbilt University, 2004

Selected Publications

  • Petit, C.S., Roczniak-Ferguson, A., Ferguson, S.M. Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases. J Cell Biol., 30;202(7):1107-112, 2013. PMID: 24081491.
  • Roczniak-Ferguson, A., Petit, C.S., Qian, S., Ky, J., Angarola, B., Froehlich, F., Walther, T.C., Ferguson, S.M. The Transcription Factor TFEB links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis. Science Signaling, Jun 12;5(228): ra42, 2012.
  • Ferguson, S.M. & De Camilli, P. Dynamin, a membrane-remodelling GTPase. Nature Reviews. Molecular Cell Biology (13(2), 75-88, 2012.



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