Michael J Higley MD,PhD

Assistant Professor of Neurobiology; Primary Member, Program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR); Member, Kavli Institute for Neuroscience

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development

Office of Student ResearchProgram in Cellular Neuroscience, Neurodegeneration and RepairInterdepartmental Neuroscience ProgramNeurobiology: Kavli Institute for Neuroscience; Swartz Program in Theoretical Neurobiology

Research Interests

Synaptic Integration; GABAergic Inhibition; Dendrites; Electrophysiology; Multiphoton Imaging more...


  • B.A., Cornell University, 1998
  • M.D./Ph.D., University of Pennsylvania, 2007

Selected Publications

  • Chiu CQ, Lur G, Morse TM, Carnevale NT, Ellis-Davies G, and Higley MJ. Compartmentalization of GABAergic inhibition by dendritic spines. Science, 340:759-62.
  • Higley MJ and Sabatini BL. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors. Nature Neuroscience 13:958-66, 2010.
  • Higley MJ*, Soler-Llavina G*, and Sabatini BL. Cholinergic modulation of multivesicular release regulates striatal synaptic potency and integration. Nature Neuroscience,12:1121-28, 2009.



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