Molecular Cell Biology, Genetics, and Development Faculty
Acar, Murat
Assistant Professor of Molecular, Cellular, and Developmental Biology
Research Interests:Systems biology, synthetic biology, gene regulatory networks, noise in gene expression, aging, evolution of gene networks.
Agaisse, Herve
Associate Professor of Microbial Pathogenesis
Research Interests:Host/pathogen interaction, microorganisms; infection; cell-to-cell spread; Listeria; Shigella; Chlamydia; Rickettsia; Vaccinia; Drosophila melanogaster; immune response; stem cells; JAK/STAT signaling; aging
Aronson, Peter
C. N. H. Long Professor of Medicine (Nephrology) and Professor of Cellular and Molecular Physiology
Research Interests:Urinary electrolyte excretion; cell membrane ion exchangers; proximal tubule
Bale, Allen
Professor of Genetics
Director, DNA Diagnostic Lab
Research Interests:Molecular Mechanisms of Cancer; Predisposition and Developmental Defects; DNA Diagnostics; Birth Defects; Cancer; Fanconi; Genetics; Hedgehog; Multiple Endocrine Neoplasia; Patched; Skin Cancer; Tumor Suppressor
Baserga, Susan
Professor of Molecular Biophysics and Biochemistry, of Genetics and of Therapeutic Radiology
Research Interests:Ribosome biogenesis; rRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing
Bewersdorf, Joerg
Assistant Professor of Cell Biology and of Biomedical Engineering
Research Interests:Super-resolution fluorescence microscopy
Bogan, Jonathan
Associate Professor of Medicine (Endocrinology) and of Cell Biology
Research Interests:Protein trafficking; ubiquitin-like modification; cell structure; insulin signaling; type 2 diabetes; metabolic diseases
Boggon, Titus
Associate Professor of Pharmacology
Research Interests:Structural biology of signal transduction
Bothwell, Alfred
Professor of Immunobiology
Director of Graduate Studies
Research Interests:Human T cell recognition; inflammation and cancer; type 1 diabetes; function of PPARs
Boulpaep, Emile
Professor of Cellular and Molecular Physiology
Director Medical Studies, Director of Graduate Studies, Cellular and Molecular Physiology
Research Interests:Electrical properties of membrane proteins in plasma membranes and junctions of renal tubule cells
Brash, Douglas
Professor of Therapeutic Radiology, of Dermatology and of Genetics
Research Interests:Ultraviolet Light; Skin Cancer
Breaker, Ronald
Henry Ford II Professor of Molecular, Cellular, and Developmental Biology
Investigator, Howard Hughes Medical Institute
Research Interests:non-coding RNA; riboswitches; ribozymes; catalytic DNA; RNA's role in evolution
Brown, Thomas
Professor of Psychology and of Cellular and Molecular Physiology
Research Interests:Neurobiological mechanism of learning and memory.
Brudvig, Gary
Eugene Higgins Professor of Chemistry and Professor of Molecular Biophysics and Biochemistry
Research Interests:photosystem II; EPR spectroscopy; metalloproteins; artificial photosynthesis
Brueckner, Martina
Associate Professor of Pediatrics (Cardiology) and of Genetics
Research Interests:Development of left-right asymmetry; Heterotaxy syndrome; Kartagener syndrome; Situs inversus
Burd, Christopher
Associate Professor of Cell Biology
Calderwood, David
Associate Professor of Pharmacology and of Cell Biology
Research Interests:Integrin; Cell adhesion; Cell migration; Cytoskeleton; Structural biology
Canessa, Cecilia
Professor of Cellular and Molecular Physiology and of Medicine (Nephrology)
Research Interests:Renal Function; Epithelial Sodium Channels
Caplan, Michael
C. N. H. Long Professor of Cellular and Molecular Physiology and Professor of Cell Biology
Chair, Cellular and Molecular Physiology
Research Interests:Ion pumps in polarized epithelia; Sorting and function
Carlson, John
Eugene Higgins Professor of Molecular, Cellular, and Developmental Biology
Research Interests:Drosophila, olfaction, taste, Anopheles, mosquito
Carroll, Topher
Associate Research Scientist in Cell Biology
Research Interests:Epigenetics; Chromosomes; Chromatin; Gene expression; Nuclear Organization; Nuclear Membrane;
Chandra, Sreeganga
Assistant Professor of Neurology and of Molecular, Cellular, and Developmental Biology
Research Interests:Presynaptic Biology; Synapse Maintenance; Parkinson's Disease; Neurodegeneration
Cheung, Kei-Hoi
Associate Professor of Anesthesiology (Medical Informatics), of Computer Science and of Genetics
Research Interests:Genetic database and tool interpolation
Chi, Tian
Associate Professor of Immunobiology
Research Interests:Epigenetic memory; transgenerational inheritance; chromatin biology
Cho, Judy
Associate Professor of Medicine (Digestive Diseases) and of Genetics
Director, Inflammatory Bowel Disease Center
Research Interests:Inflammatory Bowel Disease (IBD); identifying genetic variation that affects susceptibility to and expression of Inflammatory Bowel Disease (IBD)
Clay, Nicole
Assistant Professor of Molecular, Cellular, and Developmental Biology
Colon-Ramos, Daniel
Assistant Professor of Cell Biology
Yale Program in Cellular Neuroscience and Neurodegeneration and Repair
Research Interests:neural connectivity; brain; nematode C. elegans
Cooley, Lynn
C. N. H. Long Professor of Genetics and Professor of Cell Biology and of Molecular, Cellular, and Developmental Biology and Residential College Associate Fellow in Faculty of Arts and Sciences
Director, Combined Program in the Biological & Biomedical Sciences
Research Interests:Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function
Cresswell, Peter
Eugene Higgins Professor of Immunobiology and Professor of Cell Biology and of Dermatology
Research Interests:Molecular mechanisms of antigen processing; assembly and intracellular transport of CD1 molecules, class I and class II MHC molecules; effector functions and mechanisms of action of interferon-induced proteins; viral immunity
Crews, Craig
Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry and of Pharmacology
Executive Director, Yale Molecular Discovery Center
Research Interests:Limb regeneration; wound epidermis; blastema; natural product mode of action studies; angiogenesis; Wnt signaling; protein turnover; protein kinase regulation
De Camilli, Pietro
Eugene Higgins Professor of Cell Biology and Professor of Neurobiology
Director, Yale Program in Cellular Neuroscience and Neurodegeneration and Repair
Investigator, Howard Hughes Medical Institute
Research Interests:Synapses; exocytosis; endocytosis; membranes; clathrin; dynamin; phosphoinositides; Lowe syndrome; BAR proteins; neurodegeneration
De La Cruz, Enrique
Associate Professor of Molecular Biophysics and Biochemistry
Research Interests:Actin; Kinetics; Myosin; Nucleotide; Processivity
Dellaporta, Stephen
Professor of Molecular, Cellular, and Developmental Biology
Research Interests:Functional genomics; plant molecular genetics; marine genomics; biofuels
Deng, Xing Wang
Daniel C. Eaton Professor of Molecular, Cellular, and Developmental Biology
Daniel C. Eaton Professor of Plant Biology at Yale
Director of Peking-Yale Center for Plant Molecular Genetics & Agrobiotechnology
Research Interests:Plant Biology, Genome and Epigenome, Development mechanism, Hybrid Vigor, Agribiotechnology Light Regulation
DiGiovanna, Michael
Associate Professor of Medicine (Medical Oncology) and of Pharmacology
Research Interests:Breast cancer; HER-2/neu/ErbB-2; IGF1 receptor; EGF receptor; other growth factor receptor tyrosine protein kinases in malignancy; estrogen receptor, signal transduction
DiLeone, Ralph
Associate Professor of Psychiatry and of Neurobiology
Research Interests:Addictions; Animal Behavior Or Ethology; Animal Nutrition; Diseases and Disorders; Drugs Or Drug Abuse; Eating Disorders; Etiology; Evolution; Genetic Manipulation; Natural History; Obesity; Psychiatry
DiMaio, Daniel
Waldemar Von Zedtwitz Professor of Genetics and Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology
Scientific Director, Yale Cancer Center
Deputy Director, Yale Cancer Center
Research Interests:Molecular Biology of Tumor Viruses; Mechanisms of Viral Carcinogenesis; Molecular Basis of Cell Growth Regulation and Senescence; Manipulating Cells and Viruses with Artificial Transmembrane Proteins; Oncogenes; Sensecence; Signal Transduction; Trans-membrane Proteins; Tumor Suppressor Genes; Virology; Virus
Emonet, Thierry
Assistant Professor of Molecular, Cellular, and Developmental Biology and of Physics
Research Interests:Computational Biology chemotaxis, olfaction, immunology
Ferguson, Shawn
Assistant Professor of Cell Biology
Research Interests:lysosomes; membrane traffic; signaling; neurodegeneration; neuronal ceroid lipofuscinosis; genetics; light microscopy
Forbush, Biff
Professor of Cellular and Molecular Physiology
Research Interests:Membrane Proteins; Epithelial Transport; Ion Transport; Na-K-Cl Cotransporter; Nerve Cells; Muscle Cells
Forscher, Paul
Professor of Molecular, Cellular, and Developmental Biology
Research Interests:cytoskeleton; actin filament; microtubule; protein dynamics; axon growth; axon guidance; axon regeneration; mechanotransduction; calcium; Rho GTPase
Galan, Jorge
Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology
Chair, Section of Microbial Pathogenesis
Research Interests:Microbial Pathogenesis; host/pathogen interaction
Gallagher, Patrick
Professor of Pediatrics (Neonatology), of Genetics and of Pathology
Director, Yale Center for Blood Disorders
Director, Expression and Genomics Core, Yale Center of Excellence in Molecular Hematology
Research Interests:Neonatal hematology; Erythropoiesis; Inherited abnormalities of the erythrocyte including metabolic, membrane, and hemoglobin disorders; Sickle cell disease; Hereditary spherocytosis; Elliptocytosis; Pyropoikilocytosis; Stomatocytosis
Garcia-Castro, Martin
Associate Professor of Molecular, Cellular, and Developmental Biology
Gelernter, Joel
Foundation Professor of Psychiatry and Professor of Genetics and of Neurobiology
Director, Division of Human Genetics (Psychiatry)
Research Interests:Complex trait genetics; Psychiatric genetics; Population genetics; Substance dependence; Gene mapping
Gerstein, Mark
Albert L. Williams Professor of Biomedical Informatics
Co-Director, Yale Computational biology and Bioinformatics Program
Research Interests:Biochemistry; Bioinformatics; Biophysics; Computational Biology; DNA; Genomics; Molecular Simulation; Proteins; Sequence Alignment; Structural Biology
Giraldez, Antonio
Associate Professor of Genetics
Member of the Yale Cancer Center
Member of the Stem Cell Center
Research Interests:Non-coding RNAs, Post-transcriptional regulation; microRNAs; Developmental Biology; Gene regulatory networks; Systems Biology; Zebrafish
Glazer, Peter
Robert E. Hunter Professor of Therapeutic Radiology and Professor of Genetics
Chair, Department of Therapeutic Radiology
Research Interests:Gene targeting and gene therapy; Genetic instability in cancer; Mutagenesis; DNA repair; Radiation resistance; Cellular responses to radiation
Goodman, Andrew
Assistant Professor of Microbial Pathogenesis
Research Interests:microbiota; microbiome; genomics; gnotobiotic; germfree; symbiosis; gut; flora; bacteria; pathogen
Gorelick, Fred
Professor of Medicine (Digestive Diseases) and of Cell Biology
Associate Director, Yale M.D., Ph.D. Program
Research Interests:Exocrine pancreas; pancreatitis; intracellular proteolysis; vacuolar ATPase; AMPK; protein kinase C
Greco, Valentina
Assistant Professor of Genetics and of Dermatology
Research Interests:Organ Regeneration in Vertebrate Systems; Stem Cells; Stem Cell Niche Organization; Cancer
Groisman, Eduardo
Professor of Microbial Pathogenesis
Research Interests:bacterial genetics; signal transduction; infectious diseases; gene regulation; bacteria-host interactions; gut commensal bacteria
Gruen, Jeffrey
Professor of Pediatrics (Neonatology) and of Genetics and Associate Professor of Investigative Medicine
Research Interests:Complex inherited traits including bladder exstrophy; Genetic susceptibility to newborn disorders; The genetics of reading disability (dyslexia)
Gunel, Murat
Nixdorff-German Professor of Neurosurgery and Professor of Genetics and of Neurobiology
Co-Director, Yale Program on Neurogenetics
Director, Neurovascular Surgery
Research Interests:Molecular genetics and biology of brain aneurysms and cavernous malformations; molecular genetics of brain development
Hammarlund, Marc
Assistant Professor of Genetics
Primary Faculty, Program in Cellular Neuroscience, Neurodegeneration, and Repair
Research Interests:Axon regeneration and degeneration; Neuronal plasticity; Femtosecond laser surgery; C. elegans neurobiology
Handelsman, Jo
Professor of Molecular, Cellular, and Developmental Biology
Hashimoto, Carl
Professor of Cell Biology
Research Interests:Proteolysis; serpins; intercellular signaling; morphogenesis; disease modeling; Drosophila molecular genetics
Higley, Michael
Assistant Professor of Neurobiology
Research Interests:neural circuits; synaptic integration; neuromodulation
Hochstrasser, Mark
Eugene Higgins Professor of Molecular Biophysics and Biochemistry
Research Interests:Adenosinetriphosphatase; Cell Growth Regulation; Chemical Cleavage; Chemical Conjugate; Chimeric Protein; Enzyme Activity; Enzyme Complex; Enzyme Mechanism; Enzyme Structure; Fungal Genetics; Gene Deletion Mutation; Immunoelectron Microscopy; Isozyme; Mass Spectrometry; Mutant; Proteasome; Protein Degradation; Protein Purification; Proteinase; Protooncogene; Saccharomyces Cerevisiae; Transcription Factor; Ubiquitin
Holley, Scott
Associate Professor of Molecular, Cellular, and Developmental Biology
Research Interests:Somitogenesis Pattern Formation Morphogenesis Notch Delta Integrin emi1
Horsley, Valerie
Assistant Professor of Molecular, Cellular, and Developmental Biology
Horwich, Arthur
Sterling Professor of Genetics and Professor of Pediatrics
and Investigator HHMI
Research Interests:Chaperones in protein folding; ALS (Lou Gehrig's Disease)
Hurwitz, Michael
Assistant Professor of Medicine (Medical Oncology)
Research Interests:cell migration; kinase signaling; phosphorylation; cytoskeleton; engulfment; apoptosis; C. elegans; cancer biology
Irish, Vivian
Professor of Molecular, Cellular, and Developmental Biology and of Ecology and Evolutionary Biology
Research Interests:developmental genetics; Arabidopsis; evolution of development
Isaacs, Farren
Assistant Professor of Molecular, Cellular, and Developmental Biology
Research Interests:Synthetic Biology; Systems Biology; Genomics; Biotechnology
Ivanova, Natalia
Assistant Professor of Genetics
Research Interests:Embryonic and somatic stem cells; Vertebrate development; Functional genomics; Systems biology
Jacobs-Wagner, Christine
Professor of Molecular, Cellular, and Developmental Biology and of Microbial Pathogenesis
HHMI Investigator
Research Interests:Cell division; chromosome segregation; cell cycle coordination; cell morphogenesis, cytokeleton, cell polarity
Kavathas, Paula
Professor of Laboratory Medicine, of Genetics and of Immunobiology
Associate Chair for Research
Director, Science Education Outreach Program
Research Interests:Gene Regulation; Immunology; Molecular Cellular Entities; Receptors; Structure Or Function (Health Or Safety Or Medical); Transgenic Animals
Kazmierczak, Barbara
Associate Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis
Research Interests:Pseudomonas aeruginosa; Staphylococcus aureus; innate immunity; host-pathogen interactions; mucosal immunity
Keshishian, Haig
Professor of Molecular, Cellular, and Developmental Biology
Khokha, Mustafa
Associate Professor of Pediatrics (Critical Care) and of Genetics
Research Interests:Establishment of Vertebrate Body Plan; Embryonic Patterning and gene regulatory networks; Xenopus (frog) Genetics
Kidd, Kenneth
Professor of Genetics, of Ecology and Evolutionary Biology and of Psychiatry
Research Interests:Complex Human Disorders; Neuropsychiatric Disorders; Human Population ; Genetics; Human Evolution
Kim, In-Jung
Assistant Professor of Ophthalmology and Visual Science and of Neurobiology
Research Interests:Neuroscience; Development; Visual System; Neural Circuits; Transgenic approaches; Direction Selectivity
Kim, Tae Hoon
Assistant Professor of Genetics
Member, Yale Cancer Center
Member, Yale Stem Cell Center
Research Interests:Transcriptional Regulatory Elements and Chromatin Structure; Expression of the Cancer Genome; Epigenomics
King, Megan
Assistant Professor of Cell Biology
Research Interests:microtubules; nucleus; nuclear envelope; DNA repair; cellular mechanics; telomere biology
Koelle, Michael
Associate Professor of Molecular Biophysics and Biochemistry
Research Interests:C. Elegans; G Protein; Neurotransmission; RGS Protein; Serotonin; Molecular Genetics; Neurobiology; Neurotransmitters; Proteins and Macromolecules; Receptors
Koleske, Anthony
Professor of Molecular Biophysics and Biochemistry and of Neurobiology
Research Interests:Neuronal morphogenesis and degeneration; stress; schizophrenia; cell migration; cancer; metastasis; adhesion receptors
Konigsberg, William
Professor of Molecular Biophysics and Biochemistry
Research Interests:Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules
Krause, Diane
Professor of Laboratory Medicine, of Cell Biology and of Pathology
Assoc. Director, Yale Stem Cell Center
Assoc. Director, Transfusion Medicine Service
Director, Frisbee Laboratory for Hematopoietic Graft Engineering
Research Interests:Bone Marrow Transplantation; Stem Cells; Cell Molecular Biology; Hematology; Leukemia
Kupfer, Gary
Professor of Pediatrics (Hematology / Oncology) and of Pathology
Director, Pediatric Oncology Program
Section Chief, Pediatric Hematology/Oncology
Research Interests:Genomic instability; Development of cancer; Genetic syndrome Fanconi anemia (FA); Viral protein enhancement of cancer therapeutics
Kyriakides, Themis
Associate Professor of Pathology and of Biomedical Engineering
Research Interests:Angiogenesis; Extracellular matrix remodeling; Inflammation; Cell fusion; Wound healing; Foreign body response; Gene delivery; Biomaterials
Li, Peining
Associate Professor of Genetics
Research Interests:Cytogenetic and genomic analysis to dissect genetic mechanisms for growth regulation, mental development, and cancer progression
Lifton, Richard
Sterling Professor of Genetics and Professor of Medicine (Nephrology)
Chair, Department of Genetics
Investigator, Howard Hughes Medical Institute
Research Interests:Molecular genetics of common human diseases
Lim, Janghoo
Assistant Professor of Genetics
Program in Cellular Neuroscience, Neurodegeneration and Repair
Research Interests:Mechanisms of neurodegenerative diseases; neural development; neurodevelopmental disorders
Lin, Haifan
Professor of Cell Biology and of Genetics
Director, Yale Stem Cell Center
Research Interests:RNA-mediated epigenetic programming and translational regulation of stem cells
Lu, Jun
Assistant Professor of Genetics
Research Interests:Non-coding RNAs in blood stem cell differentiation and malignancies; MicroRNA-mediated control of embryonic stem cell fates; MicroRNA mechanisms
Lusk, Patrick
Assistant Professor of Cell Biology
Research Interests:nuclear pore complex; nuclear periphery; membrane proteins; chromatin structure
Madri, Joseph
Professor of Pathology
Research Interests:Connective tissue disorders; Cell-Matrix and Cell-Cell Interactions; Integrin-Mediated Signaling; Cardio-vascular development; Angiogenesis and Vascular Biology; inflammation; T-cell-Endothelial cell interactions
Medzhitov, Ruslan
David W. Wallace Professor of Immunobiology
Investigator, Howard Hughes Medical Institute
Research Interests:Biochemistry; Immunobiology; Immunology; Innate Immunity; Toll Receptors
Miller, Perry
Professor of Anesthesiology (Medical Informatics)
Research Interests:Biomedical informatics; Clinical informatics; Bioinformatics; Neuroinformatics
Mooseker, Mark
Ross Granville Harrison Professor of Molecular, Cellular, and Developmental Biology and Professor of Cell Biology
and Pathlogy
Research Interests:The cytoskeleton. Epithelial cell biology. molecular motors
Morrow, Jon
Raymond Yesner Professor of Pathology
Chair, Department of Pathology
Chief of Pathology at YNHH
Research Interests:Hemolytic Disease; Degenerative Brain Disease; spectrin; Autopsy Pathology; Renal Pathology; Medical Informatics; Computer Aided Instruction (CAI); Telepathology
Mothes, Walther
Associate Professor of Microbial Pathogenesis
Research Interests:cell biology; retroviral replication; retroviruses; immune; viral biology; genetic; biochemical; cell imaging; Viral entry and exit; Retroviruses including HIV
Nathanson, Michael
Professor of Medicine (Digestive Diseases) and of Cell Biology
Section Chief, Digestive Diseases
Director, Yale Liver Center
Director, Center for Cell and Molecular Imaging
Research Interests:Mechanisms and effects of calcium signals in polarized epithelia; effect of spatial organization of calcium signals on organ function regulation; factors that organize Ca2+ waves in hepatocytes; organization and effects of Ca2+ waves in cholangiocytes; mechanisms and effects of Ca2+ signals in the nucleus
Nelson, Timothy
Professor of Molecular, Cellular, and Developmental Biology
Director, Marsh Botanical Garden
Research Interests:Arabidopsis; Zea mays; vascular patterning
Nguyen, Don
Assistant Professor of Pathology
Research Interests:Metastasis; Lung cancer; Cancer genomics; Tumor microenvironment
Nitabach, Michael
Associate Professor of Cellular and Molecular Physiology and of Genetics
Research Interests:Neurophysiology; Molecular genetics; Systems Physiology; Animal Behavior
Noonan, James
Assistant Professor of Genetics
Member, Kavli Institute for Neuroscience
Member, Yale Cancer Center
Research Interests:Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates
Park, In-Hyun
Assistant Professor of Genetics
Yale Stem Cell Center
Research Interests:Reprogramming; iPS cells; ES cells; DNA methylation; epigenetics; genomics
Politi, Katerina
Assistant Professor of Medicine (Medical Oncology) and of Pathology
Research Interests:Cancer biology; Mouse models of lung cancer; Epidermal Growth Factor Receptor; ERBB Receptor family; Targeted therapy
Pollard, Thomas
Sterling Professor of Molecular, Cellular, and Developmental Biology and Professor of Cell Biology and of Molecular Biophysics and Biochemistry
Dean of the Graduate School of Arts and Sciences
Research Interests:Cytokinesis; cellular motility; role of actin filaments and myosin motors
Regan, Lynne
Professor of Molecular Biophysics and Biochemistry and of Chemistry
Research Interests:Mental retardation; protein-protein interactions; Fragile X Mental Retardation Protein (FMRP); protein-based nanomaterials
Reinisch, Karin
Associate Professor of Cell Biology
Reinke, Valerie
Associate Professor of Genetics
Research Interests:Functional genomic analysis of global gene expression mechanisms; C. elegans germline development; germline stem cells
Rimm, David
Professor of Pathology
Director of Medical Studies
Director of Pathology Tissue Services
Research Interests:Quantitative Pathology; Cancer Tissue Biomarkers; Melanoma, Breast Cancer; Cell-cell adhesion in cancer; Translation of molecular techniques to diagnostic cytopathology; General Cytopathology; Immunohistochemistry; thyroid pathology
Rinehart, Jesse
Assistant Professor of Cellular and Molecular Physiology
Research Interests:Ion Transport; Kinase/Kinome Interactions in Physiological Systems; System-Wide & Targeted Phosphoproteomics; Protein Engineering
Rodeheffer, Matthew
Assistant Professor of Comparative Medicine and of Molecular, Cellular, and Developmental Biology
Research Interests:Genomics; Stem Cells
Roeder, G Shirleen
Eugene Higgins Professor of Molecular, Cellular, and Developmental Biology and Professor of Genetics
Investigator, Howard Hughes Medical Institute
Research Interests:Meiotic Chromosome Behavior; Cell Cycle Checkpoints; Meiotic Recombination; Synaptonemal Complex
Rose, John
Professor of Pathology
Director, Molecular Virology Program
Research Interests:Virology; Vaccine and gene expression vectors based on rhabdoviruses; Membrane protein assembly, transport and targeting; Viral assembly
Rosenbaum, Joel
Professor of Molecular, Cellular, and Developmental Biology
Research Interests:Cilia, flagella, ciliopathies, organelle assembly, Intraflagellar Transport, molecular motors, kinesins and dyneins, sensory cila.
Rothman, James
Fergus F. Wallace Professor of Cell Biology and Professor of Chemistry
Chairman, Department of Cell Biology
Director, Nanobiology Institute
Research Interests:Elucidating the underlying mechanisms of vesicular transport within cells and the secretion of hormones and neurotransmitters
Schatz, David
Professor of Immunobiology
Professor of Molecular Biophysics and Biochemistry
Research Interests:Biochemical mechanism and developmental regulation of V(D)J recombination and somatic hypermutation; lymphocyte development; mechanisms of DNA repair; function of the RAG1 and RAG2 proteins; mechanisms of lymphomagenesis
Schepartz, Alanna
Milton Harris Professor of Chemistry
Professor of Molecular, Cellular, & Developmental Biology
Research Interests:Organic chemistry; chemical biology; biosynthetic engineering; drug design; synthetic biology; Novel methods to inhibit HIV infection
Schlessinger, Joseph
William H. Prusoff Professor of Pharmacology
Chair, Pharmacology
Director, Cancer Biology Institute
Research Interests:Growth factor receptors; Intracellular signaling pathways;protein kinases; phosphorylation; SH2, SH3 and other protein modules involved in signal transduction; drug discovery
Schlieker, Christian
Assistant Professor of Molecular Biophysics and Biochemistry
Research Interests:Protein folding; ubiquitin; Protein quality control and its relation to viral pathogenesis
Schwartz, Martin
New Recruit in Medicine (Cardiology)
Schwartz, Michael
Associate Professor of Neurobiology
Director, Medical Studies in Neurobiology
Asst. Dean for Curriculum, YMS
Research Interests:Mammalian Cerebral Cortex
Sessa, William
Alfred Gilman Professor of Pharmacology and Professor of Medicine (Cardiology)
Vice Chairman, Pharmacology
Director, Vascular Biology & Therapeutics Program
Research Interests:Vascular endothelium and inflammation; MiRNAs; Vascular development and angiogenesis; Lipid domains and signaling; Atherosclerosis
Shadel, Gerald
Professor of Pathology and of Genetics
Director, Graduate Studies Experimental Pathology Graduate Program
Research Interests:Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function
Shulman, Gerald
George R. Cowgill Professor of Medicine (Endocrinology) and Professor of Cellular and Molecular Physiology
Investigator, Howard Hughes Medical Institute
Research Interests:Molecular mechanisms responsible for insulin resistance
Simons, Michael
Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Cell Biology
Section Chief, Cardiovascular Medicine
Director, Yale Cardiovascular Research Center
Research Interests:Angiogenesis; Arteriogenesis; Endothelial Signaling; tyrosine kinase signaling; vascular development; FGF; VEGF; endocytosis
Slack, Frank
Professor of Molecular, Cellular, and Developmental Biology
Research Interests:microRNA; aging; cancer biology; development; RNA; c. elegans
Slayman, Clifford
Professor of Cellular and Molecular Physiology
Research Interests:Charge-dependent Transport; Proton Pumps; Potassium channels; Ribosomally Synthesized AntiMicrobial Peptides (RAMPs)
Solomon, Mark
Professor of Molecular Biophysics and Biochemistry
Research Interests:Cell cycle; Ubiquitin-mediated proteolysis; Anaphase-promoting Complex
Somlo, Stefan
C. N. H. Long Professor of Medicine (Nephrology) and Professor of Genetics
Chief, Section of Nephrology
Research Interests:Genetic kidney and liver disease; Cilia function in tissue homeostasis; Polycystin function
State, Matthew
Donald J. Cohen Professor in the Child Study Center and Professor of Genetics and of Psychiatry
Co-Director, Yale Program on Neurogenetics
Deputy Chairman for Research, Department of Psychiatry
Research Interests:Genetic mechanisms; neuropsychiatric disorders of childhood
Stein, Elke
Associate Professor of Molecular, Cellular, and Developmental Biology and of Cell Biology
Research Interests:Development of the vertebrate nervous system; Axon Guidance; Dendrite development; Synapse formation; Down Syndrome; DSCAM; Netrin and Slits and their receptors; Signal transduction
Stern, David
Professor of Pathology
Associate Director, Shared Resources, Yale Cancer Center
Leader, Signal Transduction Research Program, Yale Cancer Center
Research Interests:Cancer Biology: signal transduction by HER2/ErbB2 and other EGF family receptor tyrosine kinases; EGF family receptors in breast cancer and mammary development; DNA damage checkpoint signaling; Functional and genetic analysis of cancer; Melanoma
Strittmatter, Stephen
Vincent Coates Professor of Neurology and Professor of Neurobiology
Director, Cellular Neuroscience, Neurodegeneration and Repair
Research Interests:Axon Guidance; Axon Regeneration; Spinal Cord Injury; Molecular Biology; Stroke; Neurodegenerative Disease; Alzheimer's Disease; Fronto-Temporal Dementia
Strobel, Scott
Henry Ford II Professor of Molecular Biophysics and Biochemistry and Professor of Chemistry
Howard Hughes Medical Institute Professor
Henry Ford II Professor
Research Interests:Antibiotics; Nucleic Acid Bioorganic Chemistry; Ribosome; Ribozyme; RNA Catalysis; RNA-Protein Interaction; Translation; Riboswitches, Biofuels; Endophytes; Natural Product Discovery
Su, Bing
Associate Professor of Immunobiology
Research Interests:Kinase pathways; receptor signals; regulating cell growth
Sun, Zhaoxia
Associate Professor of Genetics
Research Interests:Zebrafish genetics; Cilium; Kidney development; Polycystic kidney disease (PKD); Size control
Sung, Patrick
Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology
Research Interests:Repair of DNA double-strand breaks; repair by homologous recombination; repair by DNA end-joining
Sutton, Richard
Associate Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis
Research Interests:HIV replication and the development of small animal models of HIV; HIV vectors; HIV replication and gene transfer into non-dividing cells
Sweasy, Joann
Professor of Therapeutic Radiology and of Genetics
Vice-Chair of Therapeutic Radiology
Research Interests:Genome Stability; Mutagenesis; DNA Replication; DNA Repair; Carcinogenesis
Takizawa, Peter
Assistant Professor of Cell Biology
Director, Medical Studies
Research Interests:Proteins; mRNA; Fluorescence-based assays; transport and translational regulation
Tattersall, Peter
Professor of Laboratory Medicine and of Genetics
Research Interests:Biochemistry; DNA Replication; Gene Therapy; Genes; Genetics; DNA Replication; Gene Therapy; Genetics; HIV/AIDS; Oncolytic Virus; Vaccines; Vectors; Viral replication and vectors; Parvoviruses
Toomre, Derek
Associate Professor of Cell Biology
Research Interests:Cell Biology; Exocytosis; Endocytosis; Membrane Traffic; Tethering; Microscopy; Live Cell Imaging; TIRFM; Single molecule
Turk, Benjamin
Associate Professor of Pharmacology
Research Interests:Cell signaling; Protein kinases; Chemical biology; Proteomics; Metalloproteases; Protein engineering
Ullu, Elisabetta
Professor of Medicine (Infectious Diseases) and of Cell Biology
Research Interests:eukaryotic cells
Vaccarino, Flora
Harris Professor in the Child Study Center and Professor of Neurobiology
Research Interests:Neural stem cells; cerebral cortex; neuronal progenitors; tyrosine kinase growth factors; excitatory neurons; GABAergic neurons; postmortem human brain;induced pluripotent stem cells; hypoxia
Vignery, Agnès
Senior Research Scientist in Orthopaedics and Rehabilitation and Associate Professor of Cell Biology
Research Interests:Differentiation mechanism of osteoblasts; Fusion mechanism of macrophages
Walther, Tobias
Associate Professor of Cell Biology
Research Interests:organelle homeostasis; plasma membrane organization, lipid metabolism; Lipid Droplets; eisosomes; sphingolipid metabolism; systematic genetics; RNAi screening; mass-spectrometry based proteomics
Walther, Zenta
Associate Professor of Pathology
Medical Director, YNHH Tumor Profiling Laboratory
Research Interests:epithelial polarity and proliferation control; intestinal epithelial homeostasis; intestinal barrier function; innate immune signalling
Wang, Tong
Professor of Cellular and Molecular Physiology
Research Interests:Kidney tubule transport; Electrolyte and acid-base balance; Transgenic animal models and human disease
Weatherbee, Scott
Assistant Professor of Genetics
Research Interests:Limb development; Developmental genetics; Organogenesis; Mouse genetics; Signaling pathways; Embryogenesis
Weissman, Sherman
Sterling Professor of Genetics
Research Interests:Globin and Histocompatibility Gene Structure and Function; Genome wide mapping of gene activity and chromosome structure in man; Transcription Factors; Lymphocyte and myeloid Transcription Networks; Stem Cells; Cell Senescence; Methods for Molecular Genetics
Wolin, Sandra
Professor of Cell Biology and of Molecular Biophysics and Biochemistry
Vice Chair, Department of Cell Biology
Research Interests:RNA quality control; noncoding RNAs; RNA damage; autoimmune disease
Xiao, Andrew
Assistant Professor of Genetics
Research Interests:Chromatin biology: histone variants, modifications and chromatin remodeling complexes; Cellular reprogramming (iPS) and stem cell biology; Mammalian neural crest cell; Mammalian DNA damage response
Xu, Tian
Professor of Genetics
Vice Chairman of Genetics
Investigator, Howard Hughes Medical Institute
Director, Yale Center for Functional Genomics
Research Interests:Genetic methodology; Cancer biology; Food and metabolism; Developmental mechanisms
Yan, Qin
Assistant Professor of Pathology
Research Interests:Epigenetics; Transcription regulation; Cancer biology; Stem cell biology
Yang, Xiaoyong
Assistant Professor of Comparative Medicine and of Cellular and Molecular Physiology
Research Interests:Nutrient Sensing; Circadian Rhythms; Metabolism; O-GlcNAc Modification; Nuclear Receptors; Diabetes; Cancer; Aging; Systems Biology
Yao, Jie
Assistant Professor of Cell Biology
Research Interests:Gene regulation; nuclear compartmentalization; protein dynamics; cellular biophysics and imaging
Zenisek, David
Associate Professor of Cellular and Molecular Physiology and of Ophthalmology and Visual Science
Research Interests:Physiology and cell biology of the presynaptic terminal; Retinal Bipolar Neuron; Synaptic Terminal, Synaptic Ribbons, Vesicle Transport; Exocytosis; Endocytosis
Zhang, Yongli
Assistant Professor of Cell Biology
Research Interests:Single-molecule biophysics and biochemistry; optical tweezers; ATP-dependent chromatin remodeling; SNAREs; membrane fusion; dynamin; membrane fission
Zhao, Hongyu
Ira V. Hiscock Professor of Public Health (Biostatistics) and Professor of Genetics and of Statistics
Research Interests:Mathematical, statistical, computational, and visualization tools to address scientific problems in molecular biology and genetics
Zhong, Weimin
Associate Professor of Molecular, Cellular, and Developmental Biology
Research Interests:asymmetric cell division; differentiation; neurogenesis; progenitor cell; self-renewal; stem cell
Zhu, Yong
Associate Professor of Epidemiology (Environmental Health)
Research Interests:Circadian genes; MicroRNAs; Shift-work; Breast Cancer; Lymphoma; Prostate Cancer


