Molecular Cell Biology, Genetics, and Development Faculty

Acar, Murat

Assistant Professor of Molecular, Cellular, and Developmental Biology

Research Interests:Systems biology, synthetic biology, gene regulatory networks, noise in gene expression, aging, evolution of gene networks.

Agaisse, Herve

Associate Professor of Microbial Pathogenesis

Research Interests:Host/pathogen interaction, microorganisms; infection; cell-to-cell spread; Listeria; Shigella; Chlamydia; Rickettsia; Vaccinia; Drosophila melanogaster; immune response; stem cells; JAK/STAT signaling; aging

Aronson, Peter

C. N. H. Long Professor of Medicine (Nephrology) and Professor of Cellular and Molecular Physiology

Research Interests:Urinary electrolyte excretion; cell membrane ion exchangers; proximal tubule

Bale, Allen

Professor of Genetics
Director, DNA Diagnostic Lab

Research Interests:Molecular Mechanisms of Cancer; Predisposition and Developmental Defects; DNA Diagnostics; Birth Defects; Cancer; Fanconi; Genetics; Hedgehog; Multiple Endocrine Neoplasia; Patched; Skin Cancer; Tumor Suppressor

Baserga, Susan

Professor of Molecular Biophysics and Biochemistry, of Genetics and of Therapeutic Radiology

Research Interests:Ribosome biogenesis; rRNA processing; U3 RNP structure and function; RNA helicases; Polymerase I transcription and processing

Bewersdorf, Joerg

Assistant Professor of Cell Biology and of Biomedical Engineering

Research Interests:Super-resolution fluorescence microscopy

Bogan, Jonathan

Associate Professor of Medicine (Endocrinology) and of Cell Biology

Research Interests:Protein trafficking; ubiquitin-like modification; cell structure; insulin signaling; type 2 diabetes; metabolic diseases

Boggon, Titus

Associate Professor of Pharmacology

Research Interests:Structural biology of signal transduction

Bothwell, Alfred

Professor of Immunobiology
Director of Graduate Studies

Research Interests:Human T cell recognition; inflammation and cancer; type 1 diabetes; function of PPARs

Boulpaep, Emile

Professor of Cellular and Molecular Physiology
Director Medical Studies, Director of Graduate Studies, Cellular and Molecular Physiology

Research Interests:Electrical properties of membrane proteins in plasma membranes and junctions of renal tubule cells

Brash, Douglas

Professor of Therapeutic Radiology, of Dermatology and of Genetics

Research Interests:Ultraviolet Light; Skin Cancer

Breaker, Ronald

Henry Ford II Professor of Molecular, Cellular, and Developmental Biology
Investigator, Howard Hughes Medical Institute

Research Interests:non-coding RNA; riboswitches; ribozymes; catalytic DNA; RNA's role in evolution

Brown, Thomas

Professor of Psychology and of Cellular and Molecular Physiology

Research Interests:Neurobiological mechanism of learning and memory.

Brudvig, Gary

Eugene Higgins Professor of Chemistry and Professor of Molecular Biophysics and Biochemistry

Research Interests:photosystem II; EPR spectroscopy; metalloproteins; artificial photosynthesis

Brueckner, Martina

Associate Professor of Pediatrics (Cardiology) and of Genetics

Research Interests:Development of left-right asymmetry; Heterotaxy syndrome; Kartagener syndrome; Situs inversus

Burd, Christopher

Associate Professor of Cell Biology

Calderwood, David

Associate Professor of Pharmacology and of Cell Biology

Research Interests:Integrin; Cell adhesion; Cell migration; Cytoskeleton; Structural biology

Canessa, Cecilia

Professor of Cellular and Molecular Physiology and of Medicine (Nephrology)

Research Interests:Renal Function; Epithelial Sodium Channels

Caplan, Michael

C. N. H. Long Professor of Cellular and Molecular Physiology and Professor of Cell Biology
Chair, Cellular and Molecular Physiology

Research Interests:Ion pumps in polarized epithelia; Sorting and function

Carlson, John

Eugene Higgins Professor of Molecular, Cellular, and Developmental Biology

Research Interests:Drosophila, olfaction, taste, Anopheles, mosquito

Carroll, Topher

Associate Research Scientist in Cell Biology

Research Interests:Epigenetics; Chromosomes; Chromatin; Gene expression; Nuclear Organization; Nuclear Membrane;

Chandra, Sreeganga

Assistant Professor of Neurology and of Molecular, Cellular, and Developmental Biology

Research Interests:Presynaptic Biology; Synapse Maintenance; Parkinson's Disease; Neurodegeneration

Cheung, Kei-Hoi

Associate Professor of Anesthesiology (Medical Informatics), of Computer Science and of Genetics

Research Interests:Genetic database and tool interpolation

Chi, Tian

Associate Professor of Immunobiology

Research Interests:Epigenetic memory; transgenerational inheritance; chromatin biology

Cho, Judy

Associate Professor of Medicine (Digestive Diseases) and of Genetics
Director, Inflammatory Bowel Disease Center

Research Interests:Inflammatory Bowel Disease (IBD); identifying genetic variation that affects susceptibility to and expression of Inflammatory Bowel Disease (IBD)

Clay, Nicole

Assistant Professor of Molecular, Cellular, and Developmental Biology

Colon-Ramos, Daniel

Assistant Professor of Cell Biology
Yale Program in Cellular Neuroscience and Neurodegeneration and Repair

Research Interests:neural connectivity; brain; nematode C. elegans

Cooley, Lynn

C. N. H. Long Professor of Genetics and Professor of Cell Biology and of Molecular, Cellular, and Developmental Biology and Residential College Associate Fellow in Faculty of Arts and Sciences
Director, Combined Program in the Biological & Biomedical Sciences

Research Interests:Molecular Genetics of Drosophila Oogenesis; Actin Cytoskeleton Regulation; Drosophila; Oogenesis; Ring Canal; Ovarian Muscle Function

Cresswell, Peter

Eugene Higgins Professor of Immunobiology and Professor of Cell Biology and of Dermatology

Research Interests:Molecular mechanisms of antigen processing; assembly and intracellular transport of CD1 molecules, class I and class II MHC molecules; effector functions and mechanisms of action of interferon-induced proteins; viral immunity

Crews, Craig

Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry and of Pharmacology
Executive Director, Yale Molecular Discovery Center

Research Interests:Limb regeneration; wound epidermis; blastema; natural product mode of action studies; angiogenesis; Wnt signaling; protein turnover; protein kinase regulation

De Camilli, Pietro

Eugene Higgins Professor of Cell Biology and Professor of Neurobiology
Director, Yale Program in Cellular Neuroscience and Neurodegeneration and Repair
Investigator, Howard Hughes Medical Institute

Research Interests:Synapses; exocytosis; endocytosis; membranes; clathrin; dynamin; phosphoinositides; Lowe syndrome; BAR proteins; neurodegeneration

De La Cruz, Enrique

Associate Professor of Molecular Biophysics and Biochemistry

Research Interests:Actin; Kinetics; Myosin; Nucleotide; Processivity

Dellaporta, Stephen

Professor of Molecular, Cellular, and Developmental Biology

Research Interests:Functional genomics; plant molecular genetics; marine genomics; biofuels

Deng, Xing Wang

Daniel C. Eaton Professor of Molecular, Cellular, and Developmental Biology
Daniel C. Eaton Professor of Plant Biology at Yale
Director of Peking-Yale Center for Plant Molecular Genetics & Agrobiotechnology

Research Interests:Plant Biology, Genome and Epigenome, Development mechanism, Hybrid Vigor, Agribiotechnology Light Regulation

DiGiovanna, Michael

Associate Professor of Medicine (Medical Oncology) and of Pharmacology

Research Interests:Breast cancer; HER-2/neu/ErbB-2; IGF1 receptor; EGF receptor; other growth factor receptor tyrosine protein kinases in malignancy; estrogen receptor, signal transduction

DiLeone, Ralph

Associate Professor of Psychiatry and of Neurobiology

Research Interests:Addictions; Animal Behavior Or Ethology; Animal Nutrition; Diseases and Disorders; Drugs Or Drug Abuse; Eating Disorders; Etiology; Evolution; Genetic Manipulation; Natural History; Obesity; Psychiatry

DiMaio, Daniel

Waldemar Von Zedtwitz Professor of Genetics and Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology
Scientific Director, Yale Cancer Center
Deputy Director, Yale Cancer Center

Research Interests:Molecular Biology of Tumor Viruses; Mechanisms of Viral Carcinogenesis; Molecular Basis of Cell Growth Regulation and Senescence; Manipulating Cells and Viruses with Artificial Transmembrane Proteins; Oncogenes; Sensecence; Signal Transduction; Trans-membrane Proteins; Tumor Suppressor Genes; Virology; Virus

Emonet, Thierry

Assistant Professor of Molecular, Cellular, and Developmental Biology and of Physics

Research Interests:Computational Biology chemotaxis, olfaction, immunology

Ferguson, Shawn

Assistant Professor of Cell Biology

Research Interests:lysosomes; membrane traffic; signaling; neurodegeneration; neuronal ceroid lipofuscinosis; genetics; light microscopy

Forbush, Biff

Professor of Cellular and Molecular Physiology

Research Interests:Membrane Proteins; Epithelial Transport; Ion Transport; Na-K-Cl Cotransporter; Nerve Cells; Muscle Cells

Forscher, Paul

Professor of Molecular, Cellular, and Developmental Biology

Research Interests:cytoskeleton; actin filament; microtubule; protein dynamics; axon growth; axon guidance; axon regeneration; mechanotransduction; calcium; Rho GTPase

Galan, Jorge

Lucille P. Markey Professor of Microbial Pathogenesis and Professor of Cell Biology
Chair, Section of Microbial Pathogenesis

Research Interests:Microbial Pathogenesis; host/pathogen interaction

Gallagher, Patrick

Professor of Pediatrics (Neonatology), of Genetics and of Pathology
Director, Yale Center for Blood Disorders
Director, Expression and Genomics Core, Yale Center of Excellence in Molecular Hematology

Research Interests:Neonatal hematology; Erythropoiesis; Inherited abnormalities of the erythrocyte including metabolic, membrane, and hemoglobin disorders; Sickle cell disease; Hereditary spherocytosis; Elliptocytosis; Pyropoikilocytosis; Stomatocytosis

Garcia-Castro, Martin

Associate Professor of Molecular, Cellular, and Developmental Biology

Gelernter, Joel

Foundation Professor of Psychiatry and Professor of Genetics and of Neurobiology
Director, Division of Human Genetics (Psychiatry)

Research Interests:Complex trait genetics; Psychiatric genetics; Population genetics; Substance dependence; Gene mapping

Gerstein, Mark

Albert L. Williams Professor of Biomedical Informatics
Co-Director, Yale Computational biology and Bioinformatics Program

Research Interests:Biochemistry; Bioinformatics; Biophysics; Computational Biology; DNA; Genomics; Molecular Simulation; Proteins; Sequence Alignment; Structural Biology

Giraldez, Antonio

Associate Professor of Genetics
Member of the Yale Cancer Center
Member of the Stem Cell Center

Research Interests:Non-coding RNAs, Post-transcriptional regulation; microRNAs; Developmental Biology; Gene regulatory networks; Systems Biology; Zebrafish

Glazer, Peter

Robert E. Hunter Professor of Therapeutic Radiology and Professor of Genetics
Chair, Department of Therapeutic Radiology

Research Interests:Gene targeting and gene therapy; Genetic instability in cancer; Mutagenesis; DNA repair; Radiation resistance; Cellular responses to radiation

Goodman, Andrew

Assistant Professor of Microbial Pathogenesis

Research Interests:microbiota; microbiome; genomics; gnotobiotic; germfree; symbiosis; gut; flora; bacteria; pathogen

Gorelick, Fred

Professor of Medicine (Digestive Diseases) and of Cell Biology
Associate Director, Yale M.D., Ph.D. Program

Research Interests:Exocrine pancreas; pancreatitis; intracellular proteolysis; vacuolar ATPase; AMPK; protein kinase C

Greco, Valentina

Assistant Professor of Genetics and of Dermatology

Research Interests:Organ Regeneration in Vertebrate Systems; Stem Cells; Stem Cell Niche Organization; Cancer

Groisman, Eduardo

Professor of Microbial Pathogenesis

Research Interests:bacterial genetics; signal transduction; infectious diseases; gene regulation; bacteria-host interactions; gut commensal bacteria

Gruen, Jeffrey

Professor of Pediatrics (Neonatology) and of Genetics and Associate Professor of Investigative Medicine

Research Interests:Complex inherited traits including bladder exstrophy; Genetic susceptibility to newborn disorders; The genetics of reading disability (dyslexia)

Gunel, Murat

Nixdorff-German Professor of Neurosurgery and Professor of Genetics and of Neurobiology
Co-Director, Yale Program on Neurogenetics
Director, Neurovascular Surgery

Research Interests:Molecular genetics and biology of brain aneurysms and cavernous malformations; molecular genetics of brain development

Hammarlund, Marc

Assistant Professor of Genetics
Primary Faculty, Program in Cellular Neuroscience, Neurodegeneration, and Repair

Research Interests:Axon regeneration and degeneration; Neuronal plasticity; Femtosecond laser surgery; C. elegans neurobiology

Handelsman, Jo

Professor of Molecular, Cellular, and Developmental Biology

Hashimoto, Carl

Professor of Cell Biology

Research Interests:Proteolysis; serpins; intercellular signaling; morphogenesis; disease modeling; Drosophila molecular genetics

Higley, Michael

Assistant Professor of Neurobiology

Research Interests:neural circuits; synaptic integration; neuromodulation

Hochstrasser, Mark

Eugene Higgins Professor of Molecular Biophysics and Biochemistry

Research Interests:Adenosinetriphosphatase; Cell Growth Regulation; Chemical Cleavage; Chemical Conjugate; Chimeric Protein; Enzyme Activity; Enzyme Complex; Enzyme Mechanism; Enzyme Structure; Fungal Genetics; Gene Deletion Mutation; Immunoelectron Microscopy; Isozyme; Mass Spectrometry; Mutant; Proteasome; Protein Degradation; Protein Purification; Proteinase; Protooncogene; Saccharomyces Cerevisiae; Transcription Factor; Ubiquitin

Holley, Scott

Associate Professor of Molecular, Cellular, and Developmental Biology

Research Interests:Somitogenesis Pattern Formation Morphogenesis Notch Delta Integrin emi1

Horsley, Valerie

Assistant Professor of Molecular, Cellular, and Developmental Biology

Horwich, Arthur

Sterling Professor of Genetics and Professor of Pediatrics
and Investigator HHMI

Research Interests:Chaperones in protein folding; ALS (Lou Gehrig's Disease)

Hurwitz, Michael

Assistant Professor of Medicine (Medical Oncology)

Research Interests:cell migration; kinase signaling; phosphorylation; cytoskeleton; engulfment; apoptosis; C. elegans; cancer biology

Irish, Vivian

Professor of Molecular, Cellular, and Developmental Biology and of Ecology and Evolutionary Biology

Research Interests:developmental genetics; Arabidopsis; evolution of development

Isaacs, Farren

Assistant Professor of Molecular, Cellular, and Developmental Biology

Research Interests:Synthetic Biology; Systems Biology; Genomics; Biotechnology

Ivanova, Natalia

Assistant Professor of Genetics

Research Interests:Embryonic and somatic stem cells; Vertebrate development; Functional genomics; Systems biology

Jacobs-Wagner, Christine

Professor of Molecular, Cellular, and Developmental Biology and of Microbial Pathogenesis
HHMI Investigator

Research Interests:Cell division; chromosome segregation; cell cycle coordination; cell morphogenesis, cytokeleton, cell polarity

Kavathas, Paula

Professor of Laboratory Medicine, of Genetics and of Immunobiology
Associate Chair for Research
Director, Science Education Outreach Program

Research Interests:Gene Regulation; Immunology; Molecular Cellular Entities; Receptors; Structure Or Function (Health Or Safety Or Medical); Transgenic Animals

Kazmierczak, Barbara

Associate Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis

Research Interests:Pseudomonas aeruginosa; Staphylococcus aureus; innate immunity; host-pathogen interactions; mucosal immunity

Keshishian, Haig

Professor of Molecular, Cellular, and Developmental Biology

Khokha, Mustafa

Associate Professor of Pediatrics (Critical Care) and of Genetics

Research Interests:Establishment of Vertebrate Body Plan; Embryonic Patterning and gene regulatory networks; Xenopus (frog) Genetics

Kidd, Kenneth

Professor of Genetics, of Ecology and Evolutionary Biology and of Psychiatry

Research Interests:Complex Human Disorders; Neuropsychiatric Disorders; Human Population ; Genetics; Human Evolution

Kim, In-Jung

Assistant Professor of Ophthalmology and Visual Science and of Neurobiology

Research Interests:Neuroscience; Development; Visual System; Neural Circuits; Transgenic approaches; Direction Selectivity

Kim, Tae Hoon

Assistant Professor of Genetics
Member, Yale Cancer Center
Member, Yale Stem Cell Center

Research Interests:Transcriptional Regulatory Elements and Chromatin Structure; Expression of the Cancer Genome; Epigenomics

King, Megan

Assistant Professor of Cell Biology

Research Interests:microtubules; nucleus; nuclear envelope; DNA repair; cellular mechanics; telomere biology

Koelle, Michael

Associate Professor of Molecular Biophysics and Biochemistry

Research Interests:C. Elegans; G Protein; Neurotransmission; RGS Protein; Serotonin; Molecular Genetics; Neurobiology; Neurotransmitters; Proteins and Macromolecules; Receptors

Koleske, Anthony

Professor of Molecular Biophysics and Biochemistry and of Neurobiology

Research Interests:Neuronal morphogenesis and degeneration; stress; schizophrenia; cell migration; cancer; metastasis; adhesion receptors

Konigsberg, William

Professor of Molecular Biophysics and Biochemistry

Research Interests:Blood Coagulation; DNA Replication; Genetics; Proteins and Macromolecules

Krause, Diane

Professor of Laboratory Medicine, of Cell Biology and of Pathology
Assoc. Director, Yale Stem Cell Center
Assoc. Director, Transfusion Medicine Service
Director, Frisbee Laboratory for Hematopoietic Graft Engineering

Research Interests:Bone Marrow Transplantation; Stem Cells; Cell Molecular Biology; Hematology; Leukemia

Kupfer, Gary

Professor of Pediatrics (Hematology / Oncology) and of Pathology
Director, Pediatric Oncology Program
Section Chief, Pediatric Hematology/Oncology

Research Interests:Genomic instability; Development of cancer; Genetic syndrome Fanconi anemia (FA); Viral protein enhancement of cancer therapeutics

Kyriakides, Themis

Associate Professor of Pathology and of Biomedical Engineering

Research Interests:Angiogenesis; Extracellular matrix remodeling; Inflammation; Cell fusion; Wound healing; Foreign body response; Gene delivery; Biomaterials

Li, Peining

Associate Professor of Genetics

Research Interests:Cytogenetic and genomic analysis to dissect genetic mechanisms for growth regulation, mental development, and cancer progression

Lifton, Richard

Sterling Professor of Genetics and Professor of Medicine (Nephrology)
Chair, Department of Genetics
Investigator, Howard Hughes Medical Institute

Research Interests:Molecular genetics of common human diseases

Lim, Janghoo

Assistant Professor of Genetics
Program in Cellular Neuroscience, Neurodegeneration and Repair

Research Interests:Mechanisms of neurodegenerative diseases; neural development; neurodevelopmental disorders

Lin, Haifan

Professor of Cell Biology and of Genetics
Director, Yale Stem Cell Center

Research Interests:RNA-mediated epigenetic programming and translational regulation of stem cells

Lu, Jun

Assistant Professor of Genetics

Research Interests:Non-coding RNAs in blood stem cell differentiation and malignancies; MicroRNA-mediated control of embryonic stem cell fates; MicroRNA mechanisms

Lusk, Patrick

Assistant Professor of Cell Biology

Research Interests:nuclear pore complex; nuclear periphery; membrane proteins; chromatin structure

Madri, Joseph

Professor of Pathology

Research Interests:Connective tissue disorders; Cell-Matrix and Cell-Cell Interactions; Integrin-Mediated Signaling; Cardio-vascular development; Angiogenesis and Vascular Biology; inflammation; T-cell-Endothelial cell interactions

Medzhitov, Ruslan

David W. Wallace Professor of Immunobiology
Investigator, Howard Hughes Medical Institute

Research Interests:Biochemistry; Immunobiology; Immunology; Innate Immunity; Toll Receptors

Melia, Thomas

Assistant Professor of Cell Biology

Research Interests:Macroautophagy; autophagy

Miller, Perry

Professor of Anesthesiology (Medical Informatics)

Research Interests:Biomedical informatics; Clinical informatics; Bioinformatics; Neuroinformatics

Mooseker, Mark

Ross Granville Harrison Professor of Molecular, Cellular, and Developmental Biology and Professor of Cell Biology
and Pathlogy

Research Interests:The cytoskeleton. Epithelial cell biology. molecular motors

Morrow, Jon

Raymond Yesner Professor of Pathology
Chair, Department of Pathology
Chief of Pathology at YNHH

Research Interests:Hemolytic Disease; Degenerative Brain Disease; spectrin; Autopsy Pathology; Renal Pathology; Medical Informatics; Computer Aided Instruction (CAI); Telepathology

Mothes, Walther

Associate Professor of Microbial Pathogenesis

Research Interests:cell biology; retroviral replication; retroviruses; immune; viral biology; genetic; biochemical; cell imaging; Viral entry and exit; Retroviruses including HIV

Nathanson, Michael

Professor of Medicine (Digestive Diseases) and of Cell Biology
Section Chief, Digestive Diseases
Director, Yale Liver Center
Director, Center for Cell and Molecular Imaging

Research Interests:Mechanisms and effects of calcium signals in polarized epithelia; effect of spatial organization of calcium signals on organ function regulation; factors that organize Ca2+ waves in hepatocytes; organization and effects of Ca2+ waves in cholangiocytes; mechanisms and effects of Ca2+ signals in the nucleus

Nelson, Timothy

Professor of Molecular, Cellular, and Developmental Biology
Director, Marsh Botanical Garden

Research Interests:Arabidopsis; Zea mays; vascular patterning

Nguyen, Don

Assistant Professor of Pathology

Research Interests:Metastasis; Lung cancer; Cancer genomics; Tumor microenvironment

Nitabach, Michael

Associate Professor of Cellular and Molecular Physiology and of Genetics

Research Interests:Neurophysiology; Molecular genetics; Systems Physiology; Animal Behavior

Noonan, James

Assistant Professor of Genetics
Member, Kavli Institute for Neuroscience
Member, Yale Cancer Center

Research Interests:Human Evolution; Evolutionary Dynamics of Gene Regulation; Synthetic Biology; Applications of Ultra-High Throughput Sequencing Technologies; Comparative and Functional Genomics in Vertebrates

Park, In-Hyun

Assistant Professor of Genetics
Yale Stem Cell Center

Research Interests:Reprogramming; iPS cells; ES cells; DNA methylation; epigenetics; genomics

Politi, Katerina

Assistant Professor of Medicine (Medical Oncology) and of Pathology

Research Interests:Cancer biology; Mouse models of lung cancer; Epidermal Growth Factor Receptor; ERBB Receptor family; Targeted therapy

Pollard, Thomas

Sterling Professor of Molecular, Cellular, and Developmental Biology and Professor of Cell Biology and of Molecular Biophysics and Biochemistry
Dean of the Graduate School of Arts and Sciences

Research Interests:Cytokinesis; cellular motility; role of actin filaments and myosin motors

Regan, Lynne

Professor of Molecular Biophysics and Biochemistry and of Chemistry

Research Interests:Mental retardation; protein-protein interactions; Fragile X Mental Retardation Protein (FMRP); protein-based nanomaterials

Reinisch, Karin

Associate Professor of Cell Biology

Reinke, Valerie

Associate Professor of Genetics

Research Interests:Functional genomic analysis of global gene expression mechanisms; C. elegans germline development; germline stem cells

Rimm, David

Professor of Pathology
Director of Medical Studies
Director of Pathology Tissue Services

Research Interests:Quantitative Pathology; Cancer Tissue Biomarkers; Melanoma, Breast Cancer; Cell-cell adhesion in cancer; Translation of molecular techniques to diagnostic cytopathology; General Cytopathology; Immunohistochemistry; thyroid pathology

Rinehart, Jesse

Assistant Professor of Cellular and Molecular Physiology

Research Interests:Ion Transport; Kinase/Kinome Interactions in Physiological Systems; System-Wide & Targeted Phosphoproteomics; Protein Engineering

Rodeheffer, Matthew

Assistant Professor of Comparative Medicine and of Molecular, Cellular, and Developmental Biology

Research Interests:Genomics; Stem Cells

Roeder, G Shirleen

Eugene Higgins Professor of Molecular, Cellular, and Developmental Biology and Professor of Genetics
Investigator, Howard Hughes Medical Institute

Research Interests:Meiotic Chromosome Behavior; Cell Cycle Checkpoints; Meiotic Recombination; Synaptonemal Complex

Rose, John

Professor of Pathology
Director, Molecular Virology Program

Research Interests:Virology; Vaccine and gene expression vectors based on rhabdoviruses; Membrane protein assembly, transport and targeting; Viral assembly

Rosenbaum, Joel

Professor of Molecular, Cellular, and Developmental Biology

Research Interests:Cilia, flagella, ciliopathies, organelle assembly, Intraflagellar Transport, molecular motors, kinesins and dyneins, sensory cila.

Rothman, James

Fergus F. Wallace Professor of Cell Biology and Professor of Chemistry
Chairman, Department of Cell Biology
Director, Nanobiology Institute

Research Interests:Elucidating the underlying mechanisms of vesicular transport within cells and the secretion of hormones and neurotransmitters

Schatz, David

Professor of Immunobiology
Professor of Molecular Biophysics and Biochemistry

Research Interests:Biochemical mechanism and developmental regulation of V(D)J recombination and somatic hypermutation; lymphocyte development; mechanisms of DNA repair; function of the RAG1 and RAG2 proteins; mechanisms of lymphomagenesis

Schepartz, Alanna

Milton Harris Professor of Chemistry
Professor of Molecular, Cellular, & Developmental Biology

Research Interests:Organic chemistry; chemical biology; biosynthetic engineering; drug design; synthetic biology; Novel methods to inhibit HIV infection

Schlessinger, Joseph

William H. Prusoff Professor of Pharmacology
Chair, Pharmacology
Director, Cancer Biology Institute

Research Interests:Growth factor receptors; Intracellular signaling pathways;protein kinases; phosphorylation; SH2, SH3 and other protein modules involved in signal transduction; drug discovery

Schlieker, Christian

Assistant Professor of Molecular Biophysics and Biochemistry

Research Interests:Protein folding; ubiquitin; Protein quality control and its relation to viral pathogenesis

Schwartz, Martin

New Recruit in Medicine (Cardiology)

Schwartz, Michael

Associate Professor of Neurobiology
Director, Medical Studies in Neurobiology
Asst. Dean for Curriculum, YMS

Research Interests:Mammalian Cerebral Cortex

Sessa, William

Alfred Gilman Professor of Pharmacology and Professor of Medicine (Cardiology)
Vice Chairman, Pharmacology
Director, Vascular Biology & Therapeutics Program

Research Interests:Vascular endothelium and inflammation; MiRNAs; Vascular development and angiogenesis; Lipid domains and signaling; Atherosclerosis

Shadel, Gerald

Professor of Pathology and of Genetics
Director, Graduate Studies Experimental Pathology Graduate Program

Research Interests:Mitochondrial Genetics and Biogenesis; Mitochondrial Dysfunction in Human Disease and Aging; Mechanisms of mtDNA Transcription and Mitochondrial Translation; Signaling Pathways that Sense and Control Mitochondrial Function

Shulman, Gerald

George R. Cowgill Professor of Medicine (Endocrinology) and Professor of Cellular and Molecular Physiology
Investigator, Howard Hughes Medical Institute

Research Interests:Molecular mechanisms responsible for insulin resistance

Simons, Michael

Robert W. Berliner Professor of Medicine (Cardiology) and Professor of Cell Biology
Section Chief, Cardiovascular Medicine
Director, Yale Cardiovascular Research Center

Research Interests:Angiogenesis; Arteriogenesis; Endothelial Signaling; tyrosine kinase signaling; vascular development; FGF; VEGF; endocytosis

Slack, Frank

Professor of Molecular, Cellular, and Developmental Biology

Research Interests:microRNA; aging; cancer biology; development; RNA; c. elegans

Slayman, Clifford

Professor of Cellular and Molecular Physiology

Research Interests:Charge-dependent Transport; Proton Pumps; Potassium channels; Ribosomally Synthesized AntiMicrobial Peptides (RAMPs)

Solomon, Mark

Professor of Molecular Biophysics and Biochemistry

Research Interests:Cell cycle; Ubiquitin-mediated proteolysis; Anaphase-promoting Complex

Somlo, Stefan

C. N. H. Long Professor of Medicine (Nephrology) and Professor of Genetics
Chief, Section of Nephrology

Research Interests:Genetic kidney and liver disease; Cilia function in tissue homeostasis; Polycystin function

State, Matthew

Donald J. Cohen Professor in the Child Study Center and Professor of Genetics and of Psychiatry
Co-Director, Yale Program on Neurogenetics
Deputy Chairman for Research, Department of Psychiatry

Research Interests:Genetic mechanisms; neuropsychiatric disorders of childhood

Stein, Elke

Associate Professor of Molecular, Cellular, and Developmental Biology and of Cell Biology

Research Interests:Development of the vertebrate nervous system; Axon Guidance; Dendrite development; Synapse formation; Down Syndrome; DSCAM; Netrin and Slits and their receptors; Signal transduction

Stern, David

Professor of Pathology
Associate Director, Shared Resources, Yale Cancer Center
Leader, Signal Transduction Research Program, Yale Cancer Center

Research Interests:Cancer Biology: signal transduction by HER2/ErbB2 and other EGF family receptor tyrosine kinases; EGF family receptors in breast cancer and mammary development; DNA damage checkpoint signaling; Functional and genetic analysis of cancer; Melanoma

Strittmatter, Stephen

Vincent Coates Professor of Neurology and Professor of Neurobiology
Director, Cellular Neuroscience, Neurodegeneration and Repair

Research Interests:Axon Guidance; Axon Regeneration; Spinal Cord Injury; Molecular Biology; Stroke; Neurodegenerative Disease; Alzheimer's Disease; Fronto-Temporal Dementia

Strobel, Scott

Henry Ford II Professor of Molecular Biophysics and Biochemistry and Professor of Chemistry
Howard Hughes Medical Institute Professor
Henry Ford II Professor

Research Interests:Antibiotics; Nucleic Acid Bioorganic Chemistry; Ribosome; Ribozyme; RNA Catalysis; RNA-Protein Interaction; Translation; Riboswitches, Biofuels; Endophytes; Natural Product Discovery

Su, Bing

Associate Professor of Immunobiology

Research Interests:Kinase pathways; receptor signals; regulating cell growth

Sun, Zhaoxia

Associate Professor of Genetics

Research Interests:Zebrafish genetics; Cilium; Kidney development; Polycystic kidney disease (PKD); Size control

Sung, Patrick

Professor of Molecular Biophysics and Biochemistry and of Therapeutic Radiology

Research Interests:Repair of DNA double-strand breaks; repair by homologous recombination; repair by DNA end-joining

Sutton, Richard

Associate Professor of Medicine (Infectious Diseases) and of Microbial Pathogenesis

Research Interests:HIV replication and the development of small animal models of HIV; HIV vectors; HIV replication and gene transfer into non-dividing cells

Sweasy, Joann

Professor of Therapeutic Radiology and of Genetics
Vice-Chair of Therapeutic Radiology

Research Interests:Genome Stability; Mutagenesis; DNA Replication; DNA Repair; Carcinogenesis

Takizawa, Peter

Assistant Professor of Cell Biology
Director, Medical Studies

Research Interests:Proteins; mRNA; Fluorescence-based assays; transport and translational regulation

Tattersall, Peter

Professor of Laboratory Medicine and of Genetics

Research Interests:Biochemistry; DNA Replication; Gene Therapy; Genes; Genetics; DNA Replication; Gene Therapy; Genetics; HIV/AIDS; Oncolytic Virus; Vaccines; Vectors; Viral replication and vectors; Parvoviruses

Toomre, Derek

Associate Professor of Cell Biology

Research Interests:Cell Biology; Exocytosis; Endocytosis; Membrane Traffic; Tethering; Microscopy; Live Cell Imaging; TIRFM; Single molecule

Turk, Benjamin

Associate Professor of Pharmacology

Research Interests:Cell signaling; Protein kinases; Chemical biology; Proteomics; Metalloproteases; Protein engineering

Ullu, Elisabetta

Professor of Medicine (Infectious Diseases) and of Cell Biology

Research Interests:eukaryotic cells

Vaccarino, Flora

Harris Professor in the Child Study Center and Professor of Neurobiology

Research Interests:Neural stem cells; cerebral cortex; neuronal progenitors; tyrosine kinase growth factors; excitatory neurons; GABAergic neurons; postmortem human brain;induced pluripotent stem cells; hypoxia

Vignery, Agnès

Senior Research Scientist in Orthopaedics and Rehabilitation and Associate Professor of Cell Biology

Research Interests:Differentiation mechanism of osteoblasts; Fusion mechanism of macrophages

Walther, Tobias

Associate Professor of Cell Biology

Research Interests:organelle homeostasis; plasma membrane organization, lipid metabolism; Lipid Droplets; eisosomes; sphingolipid metabolism; systematic genetics; RNAi screening; mass-spectrometry based proteomics

Walther, Zenta

Associate Professor of Pathology
Medical Director, YNHH Tumor Profiling Laboratory

Research Interests:epithelial polarity and proliferation control; intestinal epithelial homeostasis; intestinal barrier function; innate immune signalling

Wang, Tong

Professor of Cellular and Molecular Physiology

Research Interests:Kidney tubule transport; Electrolyte and acid-base balance; Transgenic animal models and human disease

Weatherbee, Scott

Assistant Professor of Genetics

Research Interests:Limb development; Developmental genetics; Organogenesis; Mouse genetics; Signaling pathways; Embryogenesis

Weissman, Sherman

Sterling Professor of Genetics

Research Interests:Globin and Histocompatibility Gene Structure and Function; Genome wide mapping of gene activity and chromosome structure in man; Transcription Factors; Lymphocyte and myeloid Transcription Networks; Stem Cells; Cell Senescence; Methods for Molecular Genetics