Matthew Simon

Assistant Professor of Molecular Biophysics and Biochemistry; Assistant Professor of Molecular Biophysics and Biochemistry (starting next year)

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology

Center for RNA Science and Medicine, Yale

Molecular Biophysics and Biochemistry: Cell Cycle and Transcriptional Regulation | Genomics, Genetics, and Bioinformatics | RNA Biology

Chemical Biology Institute

Research Interests

Chemical biology; Large non-coding RNAs; Epigenetic regulation; Histone modifications more...


  • B.A., Tufts University, 1999
  • Ph.D., University of California at Berkeley, 2006

Selected Publications

  • Simon, M.D., Chu, F., Racki, L.R., de la Cruz, C.C., Burlingame, A.L., Panning, B., Narlikar, G.J., and Shokat, K.M. The site-specific installation of methyl-lysine analogs into recombinant histones. Cell, 2007, 128, 1003-1012.
  • Simon, M.D., Wang C.I., Kharchenko, P., West, J.A., Chapman, B.A., Alekseyenko, A.A., Borowsky, M.L., Kuroda, M.I., Kingston, R.E. The Genomic Binding-Sites of a Non- Coding RNA. Proc Natl Acad Sci, 2011, 108, 20497-20502.



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