Karla M Neugebauer, PhD

Professor of Molecular Biophysics and Biochemistry and of Cell Biology

Research Interests

Biochemistry; Biophysics; Cell Nucleus; Cell Biology; Molecular Biology; Zebrafish; Genomics; Nuclear Cap-Binding Protein Complex; Interstitial Cells of Cajal

Research Organizations

Cancer Center: Genomics, Genetics, and Epigenetics

Center for RNA Science and Medicine, Yale

Office of Cooperative Research

Research Summary

We are interested in links between in transcription and splicing, as well as the role of cellular subcompartments in RNA biogenesis. We use imaging, techniques that capture RNA-protein interactions, and next generation sequencing as major tools. We study these phenomena in yeast (fission and budding), zebrafish and mammalian tissue culture cells.

Specialized Terms: pre-mRNA splicing, transcription, gene architecture, SR proteins, cap-binding complex, RNA-protein interactions, Cajal bodies, organization of the cell nucleus, zebrafish embryogenesis.

Selected Publications

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