Julien Berro

Assistant Professor of Molecular Biophysics and Biochemistry

Research Interests

Endocytosis; Cytoskeleton; Cell Biology; Quantitative Microsocopy; Mathematical Modeling


Research Summary

The Berro lab is interested in unraveling the molecular and biophysical mechanisms of clathrin-mediated endocytosis. We use a cross-disciplinary approach combining experimental work (genetics, cell biology, quantitative live fluorescence microscopy) and computational tools (image analysis, mathematical modeling). The Berro lab is also interested in the development of new methods for in vivo Biochemistry and Systems Biology.


Selected Publications

  • Berro J, Pollard TD. Local and global analysis of endocytic patch dynamics in fission yeast using a new "temporal super-resolution" realignment method. Mol Biol Cell. 2014 Aug 20. pii: mbc.E13-01-0004. [Epub ahead of print] PubMed PMID: 25143395.
  • Berro J, Pollard TD. Synergies between Aip1p and capping protein subunits (Acp1p and Acp2p) in clathrin-mediated endocytosis and cell polarization in fission yeast. Mol Biol Cell. 2014 Aug 20. pii: mbc.E13-01-0005. [Epub ahead of print] PubMed PMID: 25143407.
  • Akamatsu M, Berro J, Pu KM, Tebbs IR, Pollard TD. Cytokinetic nodes in fission yeast arise from two distinct types of nodes that merge during interphase. J Cell Biol. 2014 Mar 17;204(6):977-88. doi: 10.1083/jcb.201307174. PubMed PMID: 24637325; PubMed Central PMCID: PMC3998791.
  • Berro J, Sirotkin V, Pollard TD. Mathematical Modeling of Endocytic Actin Patch Kinetics in Fission Yeast: Disassembly Requires Release of Actin Filament Fragments. Molecular Biology of the Cell, 2010 Aug 15; 21 (16):2905-15.
  • Sirotkin V, Berro J, Macmillan K, Zhao L, Pollard TD. Quantitative Analysis of the Mechanism of Endocytic Actin Patch Assembly and Disassembly in Fission Yeast. Molecular Biology of the Cell, 2010 Aug 15; 21 (16):2894-904.
  • Pollard TD, Berro J. [Review] Mathematical models and simulations of cellular processes based on actin filaments. Journal of Biological Chemistry, 2009 Feb 27;284(9):5433-7
  • Michelot A (co-first author), Berro J (co-first author), Guérin C, Boujemaa-Paterski R, Staiger CJ, Martiel JL, Blanchoin L. Actin-filament stochastic dynamics mediated by ADF/cofilin. Current Biology, 2007 May 1517(10):825-33.
  • Roland J (co-first author), Berro J (co-first author), Michelot A, Blanchoin L, Martiel JL. Stochastic severing of actin filaments by actin depolymerizing factor/cofilin controls the emergence of a steady dynamical regime. Biophysical Journal, 2008 Mar 15;94(6):2082-94.
  • Berro J, Michelot A, Blanchoin L, Kovar DR, Martiel JL. Attachment conditions control actin filament buckling and the production of forces. Biophys J. 2007 Apr 1;92(7):2546-58. Epub 2007 Jan 5. PubMed PMID: 17208983; PubMed Central PMCID: PMC1864840.

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