Frederick J. Sigworth, PhD

Professor of Cellular and Molecular Physiology and of Biomedical Engineering

Departments & Organizations

Cellular & Molecular Physiology: Graduate Program in Cellular and Molecular Physiology | Membrane Biophysics | Membrane Protein Structure | Membrane Proteins - Ion Channels | Sigworth Lab

Molecular Biophysics and Biochemistry

Faculty Research

High Performance Computation

Interdepartmental Neuroscience Program

Office of Student Research

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: Membrane Biology and Motion | Molecular Medicine, Pharmacology, and Physiology: Bioengineering; Ion Channels, Pumps and Transporters; Membrane Biology and Biophysics; Neurobiology, Neural Networks and Neuropharmacology; Structural Biology | Neuroscience: Computational Neuroscience/Modeling; Neurophysiology

Office of Cooperative Research


Fred Sigworth studied applied physics at Caltech and was a graduate student at Yale, working in the laboratory of Charles F. Stevens. He received the PhD in physiology from Yale in 1979. He was a postdoc in the laboratory of Erwin Neher in Göttingen. He has been a faculty member at Yale since 1984. " How do I see the scientific enterprise? An old book puts it this way: one generation commends God's works to another. It is a great privilege to unravel the workings of ion channels, and to pass on the excitement about these molecular machines to students, colleagues and anyone else who will listen!"

Education & Training

PhD Yale University (1979)
Research Associate Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.
Post-Doctoral Fellow Max Planck Institute for Biophysical Chemistry, Göttingen, Germany.

Honors & Recognition

  • Bohmfalk Teaching PrizeYale School of Medicine (2002)

  • K. C. Cole AwardBiophysical Society (1997)

  • Yale Science and Engineering AwardYale University (1996)

  • Jacob Javits Neuroscience Investigator Award (1992)

  • Alexander von Humboldt Fellow (1979)

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