Elijah Paintsil, MBChB

Associate Professor of Pediatrics (Infectious Disease), of Epidemiology (Microbial Diseases) and of Pharmacology; Associate Professor of Pharmacology

Research Interests

Brazil; Ghana; Hepatitis C; HIV; Pediatrics; Pharmacology; Molecular Epidemiology; HIV Reverse Transcriptase; Infectious Disease Medicine

Research Summary

Research focus is on

  1. The disposition of anti-HIV drugs, e.g. nucleoside analogs such as AZT, in HIV-infected individuals in relation to treatment response, drug toxicity, and evolution of drug resistance
  2. Understanding of the dynamics of hepatitis C virus (HCV) and HIV transmission

Specialized Terms: HIV translational research; Cellular pharmacology of HIV-RT inhibitors in relation to clinical toxicities; Fitness and evolution of HIV drug resistant mutants; Molecular epidemiology and dynamics of HIV/HCV transmission

Extensive Research Description

  1. Viability of HCV in Syringes using a Novel Microculture System This study examines how long Hepatitis C virus survives in syringes at different storage conditions.
  2. HIV Nucleoside Analogs Translational Studies: Resistance and Metabolism This study will examine individual differences in intracellular concentration of nucleoside analogs in relation to toxicity and resistance evolution.
  3. Biomarkers for monitoring Pediatric HIV therapy and disease progression in resource limited setting.

Selected Publications

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