Chris Cotsapas, PhD

Assistant Professor of Neurology and of Genetics

Research Interests

Arthritis, Rheumatoid; Autoimmune Diseases; Diabetes Mellitus, Type 1; Genetics; Genetics, Medical; Genetics, Population; Graves Disease; Immune System Diseases; Lupus Erythematosus, Systemic; Multiple Sclerosis; Thyroiditis, Autoimmune; Inflammatory Bowel Diseases; Human Genome Project; Computational Biology; Autoimmune Diseases of the Nervous System; Demyelinating Autoimmune Diseases, CNS; Genomics; Genetic Research; Systems Biology

Research Organizations


Neurology: Nowak Lab

Research Summary

We look for genetic factors that predispose to disease and try to understand the biology they perturb. We ask what genes are perturbed, what processes they participate in and whether these perturbations are sufficient to induce differences at the molecular and cellular levels.This gives us novel targets for biomarkers, diagnosis and treatment.

Our approach encompasses statistical and computational tools, genetics and molecular biology. We are a hybrid lab with strong quantitative and experimental skills and we cycle between hypotheses generated by rigorous analysis and confirmation and discovery in experimental systems.

Selected Publications

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