Carson Thoreen

Assistant Professor of Cellular and Molecular Physiology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Genetics and Genomics | Molecular Medicine, Pharmacology, and Physiology

Office of Student ResearchCenter for RNA Science and Medicine, YaleCellular & Molecular Physiology

Research Interests

Growth control; RNA; Translation; Cancer biology; Signaling; Biochemistry; Bioinformatics; Metabolism more...


  • Sc.B., Brown University, 2000
  • Ph.D., Massachusettes Institute of Technology, 2008

Selected Publications

  • Thoreen CC, Chantranupong L, Keys HR, Wang T, Gray NS, Sabatini DM. (2012). A unifying model for mTORC1-mediated regulation of mRNA translation. Nature. 485:109-13.
  • Peterson TR, Laplante M, Thoreen CC, Sancak Y, Kang SA, Kuehl WM, Gray NS, Sabatini DM. (2009). DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival. Cell. 137:873-86.
  • Thoreen CC, Kang SA, Chang JW, Liu Q, Zhang J, Gao Y, Reichling LJ, Sim T, Sabatini DM, and Gray NS. (2009). An ATP-competitive inhibitor reveals rapamycin-insensitive functions of mTORC1. J Biol Chem. 284:8023-32.



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