Michael R Koelle PhD

Associate Professor of Molecular Biophysics and Biochemistry

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Office of Student ResearchInterdepartmental Neuroscience ProgramMolecular Biophysics and Biochemistry: Neurobiology

Research Interests

C. Elegans; G Protein; Neurotransmission; RGS Protein; Serotonin; Molecular Genetics; Neurobiology; Neurotransmitters; Proteins and Macromolecules; Receptors more...


  • Ph.D., Stanford University, 1992

Selected Publications

  • Bellemer, A., Hirata, T., Romer,o M.F., and Koelle, M.R. (2011). Two types of chloride transporters are required for GABA(A) receptor-mediated inhibition in C. elegans. EMBO J. 30, 1852-1863.
  • Hofler, C., and Koelle, M.R. (2011). AGS-3 alters Caenorhabditis elegans behavior after food deprivation via RIC-8 activation of the neural G protein G alpha(o). J. Neurosci. 31, 11553-11562.
  • Porter, M.Y., and Koelle, M.R. (2009). RSBP-1 is a membrane targeting subunit required by the Gaq-specific but not the Gao-specific R7 Regulator of G protein Signaling in Caenorhabditis elegans. Mol. Biol. Cell, in press.



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