Marina Picciotto PhD

Charles B. G. Murphy Professor of Psychiatry and Professor in the Child Study Center, of Neurobiology and of Pharmacology; Deputy Chair for Basic Science Research, Dept. of Psychiatry

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience | Molecular Medicine, Pharmacology, and Physiology

Office of Student ResearchInterdepartmental Neuroscience ProgramNeurobiology: Kavli Institute for Neuroscience | Pharmacology: NeuropharmacologyChild Study Center | Psychiatry: Connecticut Mental Health Center; Molecular Psychiatry, Division of; Center for Nicotine and Tobacco Use Research at Yale (CENTURY); Yale Translational Center to Develop Gender-Sensitive Treatment for Tobacco Dependence; Yale Tobacco Center of Regulatory Science

Research Interests

Neuroscience; Molecular basis of behavior; Intracellular signaling; Mouse genetic models more...


  • B.S., Stanford University, 1985
  • Ph.D., Rockefeller University, 1992

Selected Publications

  • Taylor, S.R., Badurek, S., Dileone, R.J., Nashmi, R., Minichiello, L. and Picciotto, M.R. GABAergic and glutamatergic efferents of the mouse ventral tegmental area. (2014) J Comp Neurol, 522(14):3308-34. PMC4107038
  • Mineur, Y.S., Obayemi, A., Wigestrand, M.B., Fote, G., Calarco, C.A., Li, A.M. and Picciotto, M.R. (2013) Cholinergic signaling in the hippocampus regulates social stress resilience, anxiety- and depression-like behavior, PNAS 110(9):3573-8. PMC3587265
  • McClure-Begley, T.D., Papke, R.L., Stone, K.A., Stokes, C., Levy, A.D., Gelernter, J., Xie, P., Lindstrom, J.M. and Picciotto, M.R. (2014) Rare human nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) variants affect expression and function of high affinity nicotinic acetylcholine receptors, J Pharm Exp Ther, 348(3):410-20. PMC3935145



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