Elias Lolis PhD

Professor of Pharmacology; Director of Graduate Studies

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Molecular Medicine, Pharmacology, and Physiology | Biochemistry, Biophysics and Structural Biology

Office of Student ResearchDevelopmental TherapeuticsStructural BiologyPharmacology: Lolis LabDevelopmental Therapeutics

Research Interests

Cancer; Inflammation; Infectious disease; Macromolecular X-ray crystallography; Signaling pathways; Drug design; High throughput screening (HTPS) more...


  • B.A., Columbia College, 1984
  • Ph.D., Massachusetts Institute of Technology, 1989

Selected Publications

  • Rajasekaran D, KeelerC, Syed MA, Jones MC, Harrison JK, Wu D, Bhandari V, Hodsdon ME, Lolis EJ. A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects. Biochemistry. 2012 Jul 17;51(28):5642-54.
  • Cho Y, Vermeire JJ, Merkel JS, Leng L, Du X, Bucala R, Cappello M, Lolis E. Drug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF Inhibitors. Chem Biol. 2011 Sep 23;18(9):1089-101.
  • Cho Y, Crichlow GV, Vermeire JJ, Leng L, Du X, Hodsdon ME, Bucala R, Cappello M, Gross M, Gaeta F, Johnson K, Lolis EJ. Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast. Proc Natl Acad Sci U S A. 2010 Jun 22;107(25):11313-8. Epub 2010 Jun 8.



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