Michael J Caplan, PhD, MD

C. N. H. Long Professor of Cellular And Molecular Physiology and Professor of Cell Biology; Chair, Cellular and Molecular Physiology

Departments & Organizations

Cell Biology: Membrane Traffic

Cellular & Molecular Physiology: Epithelial Transport of Ions and Solutes | Graduate Program in Cellular and Molecular Physiology | Membrane Protein Sorting and Trafficking | Membrane Proteins - Pumps and Transporters | Organ Physiology | Physiology of Human Disease

Center for Polycystic Kidney Disease Research

LCME Faculty Subcommittee

Office of Student Research

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development: Membrane Proteins; Protein Dynamics | Molecular Medicine, Pharmacology, and Physiology: Human Disease Pathology, Physiology and Intervention; Ion Channels, Pumps and Transporters; Organ Physiology; Protein Sorting and Trafficking; Receptors and Signal Transduction


Michael J. Caplan received his bachelors degree from Harvard University and his M.D. and Ph.D. degrees from Yale University in 1987. He joined Yale's Department of Cellular and Molecular Physiology as a faculty member in 1988, and is currently the C.N.H. Long Professor of Cellular and Molecular Physiology and Cell Biology.

He has received fellowships from the Helen Hay Whitney Foundation, the David and Lucille Packard Foundation for Science and Engineering, and a National Young Investigator Award from the National Science Foundation. He has also received the Young Investigator Awards from the American Physiological Society and the American Society of Nephrologists.

His work focuses on understanding the ways in which kidney cells organize and maintain their unique structures. His laboratory also studies the mechanisms responsible for Autosomal Dominant Polycystic Kidney Disease, and is working to identify targets for new therapies.

Education & Training

PhD Yale University (1987)
MD Yale University (1987)

Honors & Recognition

  • Postdoctoral Mentoring PrizeYale University (2010)

  • Bohmfalk Award for Excellence in Basic Science TeachingYale University (2000)

  • Young Investigator AwardAmerican Society of Nephrology

  • Henry P. Bowditch Award LectureshipAmerican Physiological Society

  • National Young Investigator AwardNational Science Foundation

  • Charles W. Bohmfalk Teaching PrizeYale School of Medicine

International Activity

  • Advisory Board of Telethon Italia Italy (2009 - 2011)

    Serves on the scientific advisory board of Telethon Italia, a group of scientists of international standing, whose members are asked to review research grants, fellowships and career applications deriving from competitive calls

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