Research Areas

The broad scope of faculty interest means that opportunities exist for laboratory rotations and thesis dissertation research covering a wide range of microbiological topics.

Bacteria

Bacteria are a major topic of interest among the Yale Microbiology Track faculty.  Specific areas of interest include molecular mechanisms of bacterial pathogenesis; bacterial secretion and effector systems; bacterial signal transduction networks, bacterial cell morphology; and bacterial manipulation of host physiology and innate immune responses.


Environmental Microbiology

Faculty interests also encompass environmental microbiology and microbial ecology, with a particular emphasis on interactions between microbes and environmental contaminants.


    Immunology & Host Response

    Immunology and the host response to infection is a major area of interest among our Faculty. Specific topics of interest include the role of cytokines in the host response to infection; mechanisms of pathogen detection and elimination by innate immune detection and effector systems; and the role of adaptive immune response to infection.


      Molecular Genetics

      Several Yale faculty have combined interests in microbiology and molecular genetics.  Research topics of interest include DNA recombination and repair; structure and enzymatic function of nucleic acids and proteins; molecular biology of ion movement across membranes; and molecular mechanisms of cell differentiation and cell cycle progression. 


      Parasites

      Researchers at Yale study a wide variety of eukaryotic parasites including parasitic fungi, intracellular protozoa, and helminth worms.  Current topics of interest include cellular and molecular strategies used for cellular entry and immune evasion; transcription and RNA processing in protozoa; and the interaction of parasites with their vectors.


        Viruses

        The study of viruses is a major area of focus at Yale.  Specific areas of interest include the pathogenesis of human and animal viruses; host antiviral defense mechanisms; the molecular biology of viral replication and cellular transformation; the assembly and entry of viruses into new cells; and the development of novel antiviral compounds.

        Faculty members occupy space on Science Hill and at the School of Medicine. Facilities have the latest instruments necessary for research in modern microbiology. Special laboratory facilities for the bio-containment of infectious agents and for rearing and studying insect vectors are also available.