Cell Cycle and Signal Transduction
Control of the cell cycle, cell signaling, Protein kinases, Chemical genetics, Proteomics.
Replication, Recombination, Repair, Transposition, Chromosome structure, Functional genomics.
Drug Design, Discovery and Mechanism
Membrane Biology and Motion
Transmembrane signalling, Vesicle transport, Growth factor receptors, Membrane channels, Cytoskeleton.
Protein Folding, Dynamics and Degradation
Chaperone structure and function, protein design, the proteasome, amyloid fibril formation, ubiquitin-mediated proteolysis.
RNA Catalysis and Ribonucleoprotein Machines
Self-splicing introns and spliceosomes, RNA stability and qulity control, RNA editing and modification, Ribosome structure and function, tRNA recognition and biosynthesis, HIV reverse transcriptase.
RNA polymerase, Transcription factors, Lymphocyte activation.
Virology, Infection and Immunity
The following are faculty who are addressing problems using crystallography, NMR, mass spectrometry, cryo-electron microscopy, or computational methods.