Enrique M. De La Cruz, PhD

Professor of Molecular Biophysics and Biochemistry

Departments & Organizations

Molecular Biophysics and Biochemistry: E De La Cruz Lab

Faculty Research


Office of Student Research

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: Membrane Biology and Motion

Office of Cooperative Research


Enrique M. De La Cruz, Ph.D. is a Professor in the Department of Molecular Biophysics and Biochemistry at Yale University. He is a first generation Cuban-American who was raised in Newark, NJ. Dr. De La Cruz received his undergraduate degree in Biology from Rutgers University where he was inducted into Phi Beta Kappa and Beta Beta Beta Honor Societies. He earned his Ph.D. degree in Biochemistry, Cell & Molecular Biology (BCMB) with Dr. Thomas D. Pollard at Johns Hopkins University School of Medicine and received postdoctoral training in the laboratories of Dr. H. Lee Sweeney and E. Michael Ostap at the University of Pennsylvania School of Medicine. In 2009, he was a Visiting Scientist at Centre National de la Recherche Scientifique (CNRS), Commissariat à l'Énergie Atomique (CEA) & Université Joseph Fourier in Grenoble, France. He was a Mayent-Rothschild Senior Research Fellow at the Institut Curie in Paris, France in 2015, and recipient of an Invited Professor Fellowship at the ESPCI Paris Tech (école supérieure de physique et de chimie industrielles de la ville de Paris) in 2016.

Dr. De La Cruz has published extensively in the areas of actin and myosin regulation, RNA helicases, and signaling enzymes, for which he has received a number of awards and honors. Among them are the American Heart Association Established Investigator Award, NSF CAREER award, Keith R. Porter Symposium Award from the Society for General Physiologists and a Hellman Family Fellowship. He was also the Abbott Distinguished Lecturer at Purdue University, a Plenary Lecturer at the Ibero-American Congress of Biophysics Meeting held in Brazil, and a Plenary Lecturer of the 44th Annual Meeting of the Biophysical Society of Japan.

Dr. De La Cruz is actively involved with various scientific societies, journals and peer review committees. He serves on the Editorial Board of Journal of Biological Chemistry, Biophysical Journal and Biophysical Reviews, the Publications and Meetings Committees of the American Society for Biochemistry & Molecular Biology (ASBMB). He has served on the Biophysical Society Council, chaired its Nominating Committee, the Macromolecular Structure & Function C Study Section of the National Institutes of Health, and served on research panels for the NSF, American Heart Association as well as funding agencies in England, Israel and France. In addition, he actively participates in a number of outreach activities focused on enhancing minority participation and career development in the sciences.

Education & Training

PhD Johns Hopkins University School of Medicine (1997)

Honors & Recognition

  • Established Investigator AwardAmerican Heart Association (2009)

  • NSF CAREER AwardNSF (2006)

  • Abbott Distinguished Lecturer Purdue University (2003)

  • Keith R. Porter Symposium AwardSociety for General Physiologists (2001)

  • Life Sciences Research Foundation Postdoctoral Fellowship AwardLife Sciences Research Foundation (1998)

  • Commencement SpeakerJohns Hopkins University School of Medicine (1997)

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