Anna Marie Pyle
William Edward Gilbert Professor of Molecular, Cellular, and Developmental Biology and Professor of Chemistry; Director, Division of Biological Sciences
Departments & Organizations
Molecular, Cellular, and Developmental Biology
Biological and Biomedical Sciences (BBS): Computational Biology and Bioinformatics | Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology: RNA Catalysis and Ribonucleoprotein Machines
Molecular Virology
Structural Biology
Center for RNA Science and Medicine, Yale
RNA Biology
Structural Biology
Mechanisms of Viral Pathogenesis
Molecular Virology
Research Interests
Structure and function of catalytic RNA; RNA helicase mechanisms; Computational analysis of RNA structure more...
Selected Publications
- Dumont, S., et al. (2006). RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP. Nature 439:105-108.
- Solem, A., Zingler, N., and Pyle, A.M. (2006). A DEAD protein that activates intron self-splicing without unwinding RNA. Mol. Cell 24:611-617.
- Toor, N., Keating, K. S., Taylor, S. D. and Pyle, A. M. Crystal structure of a self-spliced group II intron. Science 320, 77-82 (2008)
