Thomas Melia PhD

Associate Professor of Cell Biology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Office of Student ResearchCell Biology: Membrane Traffic; Melia Lab

Research Interests

Macroautophagy; Autophagy more...


  • BS, Carnegie Mellon Univ, 1992
  • Ph.D., Baylor College of Medicine, 1999

Selected Publications

  • Nath S, Dancourt J, Shteyn V, Puente G, Fong WM, Nag S, Bewersdorf J, Yamamoto A, Antonny B, Melia TJ. 2014. Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3. Nature Cell Biology, 16(5), p 415-424.
  • Choy, A., J. Dancourt, B. Mugo, T.J. O'Connor, R.R. Isberg, T.J. Melia*, and C.R. Roy. 2012. The Legionella effector RavZ inhibits host autophagy through irreversible Atg8 deconjugation. Science, 338(6110): p. 1072-6.
  • Usha Nair, Anjali Jotwani, Jiefei Geng, Noor Gammoh, Diana Richerson, Wei-Lien Yen, Janice Griffith, Shanta Nag, Ke Wang, Tyler Moss, Fulvio Reggiori, Misuzu Baba, James A. McNew, Xuejun Jiang, Thomas J. Melia*, and Daniel J. Klionsky*. 2011. SNARE proteins are required for macroautophagy. Cell, 146(2), p 290-302.



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