I George Miller, Jr, MD

John F. Enders Professor of Pediatrics (Infectious Disease) and Professor of Epidemiology (Microbial Diseases) and of Molecular Biophysics and Biochemistry; Section Chief, Pediatric Infectious Diseases

Departments & Organizations

Molecular Biophysics and Biochemistry: Mechanisms of Viral Pathogenesis

School of Public Health: Epidemiology of Microbial Diseases

Cancer Center: Virus and Other Infection-associated Cancers

Faculty Research

Molecular Virology: Virology laboratories

Pediatrics

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Biochemistry, Biophysics and Structural Biology: Transcriptional Regulation; Virology, Infection and Immunity | Microbiology: Molecular Genetics; Viruses

Yale Medicine

Office of Cooperative Research

Biography

Dr. Miller’s laboratory studies the mechanisms underlying the switch between latency and lytic replication of two oncogenic herpesviruses, Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus. Current experiments explore how viral and cellular transcription factors that selectively bind to methylated DNA control expression of viral and cellular genes, how cellular gene expression is selectively inhibited while viral gene expression is enhanced, and how viral DNA replication is regulated by cellular proteins. Recent studies focus on a new class of anti-viral agents that inhibit reactivation of Epstein-Barr virus from latency into lytic infection.

Education & Training

AB Harvard College (1968)
MD Harvard Medical School (1962)
Research Fellow Children's Hospital, Boston
Research Fellow Harvard Medical School
Intern & Assistant Resident University Hospital, Cleveland
Board Certification AB of Internal Medicine, Internal Medicine (1972)

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Contact Info

I George Miller, Jr, MD
Patient Care Locations
Yale Pediatric Infectious DiseasesYale-New Haven Children's Hospital
1 Park Street, Ste West Pavilion - 2nd Floor

New Haven, CT 06504
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Yale Pediatric Infectious DiseaseYale-New Haven Hospital
20 York Street

New Haven, CT 06510
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Mailing Address
PO Box 208064
New Haven, CT 06520-8064