Clinical Core

Led by Christopher H. van Dyck, MD and Arash Salardini, MD, the Clinical Core aims to perform research diagnostic evaluations for a large clinical population. Participants are followed longitudinally to provide well-characterized subjects for research projects conducted by ADRC investigators and collaborators. The Core also makes data available to the National Alzheimer’s Coordinating Center (NACC) for national studies. The Core focuses on cell biology, integration of translational neuroscience, and systematic storage of biospecimens for current and future biomarker studies. The Core thus supplies biorepositories for whole blood (for DNA), serum, plasma, cerebrospinal fluid (CSF), and peripheral blood mononuclear cells (PMCs) for the generation of induced pluripotent stem cells (iPSCs).

The Clinical Core is currently seeking participants with Alzheimer’s and other dementias, as well as Mild Cognitive Impairment (MCI). The Core is also enrolling cognitively normal individuals with and without first-degree family history of Alzheimer’s disease.

The staff of the Clinical Core meets weekly to review clinical cases and to discuss other Core issues.

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Susan Possidente Good

Nurse Practitioner Psychiatry

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Keith A Hawkins, PsyD

Professor of Psychiatry

Director, Neuropsychological Assessment Service, Psychiatry

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Arash Salardini, MD

Assistant Professor of Neurology

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Emily Schoenhofen Sharp, PhD, ABPP

Assistant Professor of Neurology

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Christopher H Van Dyck, MD

Professor of Psychiatry, Neurology, and Neuroscience

Director, Alzheimer's Disease Research Unit

Director, Yale Alzheimer's Disease Research Center

Director, Division of Aging and Geriatric Psychiatry

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