Z. Ping Lin PhD

Associate Research Scientist in Pharmacology

Departments & Organizations

Pharmacology


Research Interests

Homologous Recombination Repair; Assay Development; High-Throughput and In Silico Screening; Drug Development; Synthetic Lethality; Chemoresistance; Cancer Stem Cells.  more...


Education

  • B.S., Taipei Medical College, 1991
  • Ph.D., George Washington University Medical Center, 1999

Selected Publications

  • Lin, Z.P., Ratner, E.S., Whicker, M.E., Lee, Y., and Sartorelli, A.C. Triapine disrupts CtIP-mediated homologous recombination repair and sensitizes ovarian cancer cells to poly(ADP-ribose) polymerase and topoisomerase inhibitors. Mol. Cancer Res. 12: 381-393 (2014).
  • Ratner, E.S., Sartorelli, A.C., and Lin, Z.P. Poly (ADP-ribose) polymerase inhibitors: on the horizon of tailored and personalized therapies for epithelial ovarian cancer. Curr Opin Oncol. 24: 564-71 (2012).
  • Lin, Z.P., Lee, Y., Lin, F., Belcourt, M.F., Li, P., Cory, J.G., Glazer, P.M., and Sartorelli, A.C. Reduced level of ribonucleotide reductase R2 subunits increases dependence on homologous recombination repair of cisplatin-induced DNA damage. Mol. Pharmacol. 80: 1000-1012 (2011).

more...

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